| Literature DB >> 2901570 |
R I Hallan1, N S Williams, J Melling, D J Waldron, N R Womack, J F Morrison.
Abstract
In seven patients with anismus the striated sphincter muscle complex was selectively weakened by local injection of Clostridium botulinum type A toxin. Symptom scores improved significantly and correlated with a significant reduction in the maximum voluntary and canal squeeze pressure and a significant increase in the anorectal angle on straining. Botulinum A toxin seems to be promising treatment for some patients with anismus.Entities:
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Year: 1988 PMID： 2901570 DOI： 10.1016/s0140-6736(88)90188-2
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321