Literature DB >> 2900038

Bradykinin analogues: differential agonist and antagonist activities suggesting multiple receptors.

K M Braas1, D C Manning, D C Perry, S H Snyder.   

Abstract

Bradykinin analogues with specific antagonist activity in several bioassays were evaluated for effects on [3H]-bradykinin receptor binding sites and inositol phosphate production in neuroblastoma N1E-115 cells. The analogues varied in their affinities for bradykinin receptors in guinea-pig ileum and N1E-115 cell membranes, in their effects on uterine and ileal contractions and in their agonist or antagonist activity on phosphoinositide turnover in N1E-115 cells. These tissue specific effects suggest the presence of multiple bradykinin receptor subtypes.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 2900038      PMCID： PMC1853931          DOI： 10.1111/j.1476-5381.1988.tb11492.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  7 in total

1.  Bradykinin receptor-mediated cyclic GMP formation in a nerve cell population (murine neuroblastoma clone N1E-115).

Authors:  R M Snider; E Richelson
Journal:  J Neurochem       Date:  1984-12       Impact factor: 5.372

2.  Two bradykinin binding sites with picomolar affinities.

Authors:  D C Manning; R Vavrek; J M Stewart; S H Snyder
Journal:  J Pharmacol Exp Ther       Date:  1986-05       Impact factor: 4.030

3.  Induction of differentiation increases Met5-enkephalin and Leu5-enkephalin content in NG108-15 hybrid cells: an immunocytochemical and biochemical analysis.

Authors:  K M Braas; S R Childers; D C U'Prichard
Journal:  J Neurosci       Date:  1983-09       Impact factor: 6.167

4.  Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands.

Authors:  M J Berridge; C P Downes; M R Hanley
Journal:  Biochem J       Date:  1982-09-15       Impact factor: 3.857

5.  Bradykinin-induced transient accumulation of inositol trisphosphate in neuron-like cell line NG108-15 cells.

Authors:  K Yano; H Higashida; H Hattori; Y Nozawa
Journal:  FEBS Lett       Date:  1985-02-25       Impact factor: 4.124

6.  Competitive antagonists of bradykinin.

Authors:  R J Vavrek; J M Stewart
Journal:  Peptides       Date:  1985 Mar-Apr       Impact factor: 3.750

7.  Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.

Authors:  M J Berridge; R M Dawson; C P Downes; J P Heslop; R F Irvine
Journal:  Biochem J       Date:  1983-05-15       Impact factor: 3.857
  7 in total
  12 in total

Review 1.  Bradykinin and asthma.

Authors:  P J Barnes
Journal:  Thorax       Date:  1992-11       Impact factor: 9.139

2.  Bradykinin stimulates production of inositol (1,4,5) trisphosphate in cultured mesangial cells of the rat via a BK2-kinin receptor.

Authors:  J L Bascands; C Emond; C Pecher; D Regoli; J P Girolami
Journal:  Br J Pharmacol       Date:  1991-04       Impact factor: 8.739

3.  Activation of a bradykinin receptor in peripheral nerve and spinal cord in the neonatal rat in vitro.

Authors:  A Dray; J Bettaney; P Forster; M N Perkins
Journal:  Br J Pharmacol       Date:  1988-12       Impact factor: 8.739

4.  Selectivity of bradykinin analogues for receptors mediating contraction and relaxation of the rat duodenum.

Authors:  A C Paiva; T B Paiva; C C Pereira; S I Shimuta
Journal:  Br J Pharmacol       Date:  1989-09       Impact factor: 8.739

5.  Agonistic and antagonistic properties of the bradykinin B2 receptor antagonist, Hoe 140, in isolated blood vessels from different species.

Authors:  M Félétou; M Germain; C Thurieau; J L Fauchère; E Canet
Journal:  Br J Pharmacol       Date:  1994-06       Impact factor: 8.739

6.  Expression cloning of a rat B2 bradykinin receptor.

Authors:  A E McEachern; E R Shelton; S Bhakta; R Obernolte; C Bach; P Zuppan; J Fujisaki; R W Aldrich; K Jarnagin
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

7.  Identification of a B2 bradykinin receptor expressed by PC12 pheochromocytoma cells.

Authors:  J Nardone; C Gerald; L Rimawi; L Song; P G Hogan
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

8.  Cardiovascular effects of intrathecally administered bradykinin in the rat: characterization of receptors with antagonists.

Authors:  P Lopes; D Regoli; R Couture
Journal:  Br J Pharmacol       Date:  1993-12       Impact factor: 8.739

9.  The neuropeptide bradykinin stimulates phosphoinositide turnover in HSDM1C1 cells: B2-antagonist-sensitive responses and receptor binding studies.

Authors:  N A Sharif; R L Whiting
Journal:  Neurochem Res       Date:  1993-12       Impact factor: 3.996

10.  Bradykinin-stimulated phosphoinositide metabolism in cultured canine tracheal smooth muscle cells.

Authors:  C M Yang; H C Hsia; S P Chou; R Ong; J T Hsieh; S F Luo
Journal:  Br J Pharmacol       Date:  1994-01       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.