Janet Schloss1, Maree Colosimo2. 1. Office of Research, Endeavour College of Natural Health, Brisbane, 4006, Australia. janet.schloss@endeavour.edu.au. 2. Medical Oncology Group of Australia, Clinical Oncology Society of Australia, Queensland Clinical Oncology Group, Brisbane, 4000, Australia.
Abstract
PURPOSE OF REVIEW: The purpose of this mini review is to evaluate the literature on B vitamins and chemotherapy-induced peripheral neuropathy. RECENT FINDINGS: One hundred and five journal articles were evaluated and nine manuscripts were included. There was one in vitro, one was an animal and seven were human studies. The in vitro study was a safety study on vitamin B6 and oxaliplatin which was not directly related to CIPN. The animal study evaluated vitamin B3 on paclitaxel administration with positive results. The human studies varied using a vitamin B complex, vitamin B12 only and vitamin B6. Chemotherapy-induced peripheral neuropathy (CIPN) continues to plague patients and the medical fraternity. Currently, there are still no conclusive protective or treatment options. B vitamins have been found to play a role in CIPN prevention, but further studies are required to ascertain possible protection and treatment options.
PURPOSE OF REVIEW: The purpose of this mini review is to evaluate the literature on B vitamins and chemotherapy-induced peripheral neuropathy. RECENT FINDINGS: One hundred and five journal articles were evaluated and nine manuscripts were included. There was one in vitro, one was an animal and seven were human studies. The in vitro study was a safety study on vitamin B6 and oxaliplatin which was not directly related to CIPN. The animal study evaluated vitamin B3 on paclitaxel administration with positive results. The human studies varied using a vitamin B complex, vitamin B12 only and vitamin B6. Chemotherapy-induced peripheral neuropathy (CIPN) continues to plague patients and the medical fraternity. Currently, there are still no conclusive protective or treatment options. B vitamins have been found to play a role in CIPN prevention, but further studies are required to ascertain possible protection and treatment options.
Entities:
Keywords:
B vitamins; CIPN; Chemotherapy-induced peripheral neuropathy; Vitamin B12
Authors: Vijaya Kancherla; John L Elliott; Birju B Patel; N Wilson Holland; Theodore M Johnson; Anjali Khakharia; Lawrence S Phillips; Godfrey P Oakley; Camille P Vaughan Journal: J Am Geriatr Soc Date: 2017-02-09 Impact factor: 5.562
Authors: Marta V Hamity; Stephanie R White; Roxanne Y Walder; Mark S Schmidt; Charles Brenner; Donna L Hammond Journal: Pain Date: 2017-05 Impact factor: 6.961
Authors: Sherry L Wolf; Debra L Barton; Rui Qin; Edward J Wos; Jeff A Sloan; Heshan Liu; Neil K Aaronson; Daniel V Satele; Bassam I Mattar; Nathan B Green; Charles L Loprinzi Journal: Support Care Cancer Date: 2011-04-12 Impact factor: 3.603
Authors: P H Wiernik; B Yeap; S E Vogl; B H Kaplan; R L Comis; G Falkson; T E Davis; E Fazzini; B Cheuvart; J Horton Journal: Cancer Invest Date: 1992 Impact factor: 2.176
Authors: Janna L Koole; Martijn J L Bours; Anne J M R Geijsen; Biljana Gigic; Arve Ulvik; Dieuwertje E Kok; Stefanie Brezina; Jennifer Ose; Andreas Baierl; Jürgen Böhm; Hermann Brenner; Stéphanie O Breukink; Jenny Chang-Claude; Fränzel J B van Duijnhoven; Peter van Duijvendijk; Tanja Gumpenberger; Nina Habermann; Henk K van Halteren; Michael Hoffmeister; Andreana N Holowatyj; Maryska L G Janssen-Heijnen; Eric T P Keulen; Rama Kiblawi; Flip M Kruyt; Christopher I Li; Tengda Lin; Øivind Midttun; Anita R Peoples; Eline H van Roekel; Martin A Schneider; Petra Schrotz-King; Alexis B Ulrich; Kathy Vickers; Evertine Wesselink; Johannes H W de Wilt; Andrea Gsur; Per M Ueland; Cornelia M Ulrich; Ellen Kampman; Matty P Weijenberg Journal: Am J Clin Nutr Date: 2021-06-01 Impact factor: 7.045
Authors: Jae-Seok Min; Chang Min Lee; Sung Il Choi; Kyung Won Seo; Do Joong Park; Yong Hae Baik; Myoung-Won Son; Won Hyuk Choi; Sungsoo Kim; Kyung Ho Pak; Min Gyu Kim; Joong-Min Park; Sang Ho Jeong; Moon-Soo Lee; Sungsoo Park Journal: J Gastric Cancer Date: 2018-09-07 Impact factor: 3.720
Authors: Bruce H R Wolffenbuttel; Hanneke J C M Wouters; M Rebecca Heiner-Fokkema; Melanie M van der Klauw Journal: Mayo Clin Proc Innov Qual Outcomes Date: 2019-05-27
Authors: Hsing-Wei Hung; Chien-Ying Liu; Hsiu-Fang Chen; Chun-Chu Chang; Shu-Ching Chen Journal: Int J Environ Res Public Health Date: 2021-05-26 Impact factor: 3.390