Gabriëlla A M Blokland1, Elisabetta C Del Re2, Raquelle I Mesholam-Gately3, Jorge Jovicich4, Joey W Trampush5, Matcheri S Keshavan6, Lynn E DeLisi7, James T R Walters8, Jessica A Turner9, Anil K Malhotra10, Todd Lencz10, Martha E Shenton11, Aristotle N Voineskos12, Dan Rujescu13, Ina Giegling14, René S Kahn15, Joshua L Roffman16, Daphne J Holt16, Stefan Ehrlich17, Zora Kikinis18, Paola Dazzan19, Robin M Murray19, Marta Di Forti19, Jimmy Lee20, Kang Sim20, Max Lam20, Rick P F Wolthusen17, Sonja M C de Zwarte15, Esther Walton15, Donna Cosgrove21, Sinead Kelly22, Nasim Maleki16, Lisa Osiecki23, Marco M Picchioni19, Elvira Bramon24, Manuela Russo19, Anthony S David19, Valeria Mondelli19, Antje A T S Reinders19, M Aurora Falcone19, Annette M Hartmann14, Bettina Konte14, Derek W Morris25, Michael Gill26, Aiden P Corvin26, Wiepke Cahn15, New Fei Ho20, Jian Jun Liu27, Richard S E Keefe28, Randy L Gollub16, Dara S Manoach16, Vince D Calhoun29, S Charles Schulz30, Scott R Sponheim30, Donald C Goff31, Stephen L Buka32, Sara Cherkerzian33, Heidi W Thermenos34, Marek Kubicki35, Paul G Nestor36, Erin W Dickie37, Evangelos Vassos19, Simone Ciufolini19, Tiago Reis Marques19, Nicolas A Crossley19, Shaun M Purcell38, Jordan W Smoller1, Neeltje E M van Haren15, Timothea Toulopoulou39, Gary Donohoe40, Jill M Goldstein41, Larry J Seidman34, Robert W McCarley7, Tracey L Petryshen42. 1. Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States. 2. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, MA, United States; Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States. 3. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Massachusetts Mental Health Center Public Psychiatry Division, Beth Israel Deaconess Medical Center, Boston, MA, United States. 4. Center for Mind/Brain Sciences (CiMEC), University of Trento, Trento, Italy. 5. Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Division of Northwell Health, Manhasset, NY, United States; Division of Psychiatry Research, The Zucker Hillside Hospital, Division of Northwell Health, Glen Oaks, NY, United States; Hofstra Northwell School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, United States; BrainWorkup, LLC, Los Angeles, CA, United States. 6. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Massachusetts Mental Health Center Public Psychiatry Division, Beth Israel Deaconess Medical Center, Boston, MA, United States; University of Pittsburgh Medical Center, Pittsburgh, PA, United States. 7. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, MA, United States. 8. Department of Psychological Medicine, Cardiff University, Cardiff, United Kingdom. 9. The Mind Research Network, Albuquerque, NM, United States; Department of Psychology and Neuroscience Institute, Georgia State University, GA, United States. 10. Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Division of Northwell Health, Manhasset, NY, United States; Division of Psychiatry Research, The Zucker Hillside Hospital, Division of Northwell Health, Glen Oaks, NY, United States; Hofstra Northwell School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, United States. 11. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, MA, United States; Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. 12. Kimel Family Translational Imaging Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Department of Psychiatry and Institute of Medical Science, University of Toronto, Toronto, ON, Canada. 13. Department of Psychiatry, Psychotherapy and Psychosomatics, University of Halle-Wittenberg, Halle, an der Saale, Germany; Department of Psychiatry, Ludwig Maximilians University, Munich, Germany. 14. Department of Psychiatry, Psychotherapy and Psychosomatics, University of Halle-Wittenberg, Halle, an der Saale, Germany. 15. Brain Centre Rudolf Magnus, Department of Psychiatry, University Medical Centre Utrecht, Utrecht, The Netherlands. 16. Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States. 17. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; Division of Psychological & Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technische Universität Dresden, Dresden, Germany. 18. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States. 19. Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom; National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, London, United Kingdom. 20. Institute of Mental Health, Woodbridge Hospital, Singapore. 21. The Cognitive Genetics and Cognitive Therapy Group, Department of Psychology, National University of Ireland, Galway, Ireland. 22. Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland; Laboratory of NeuroImaging, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. 23. Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, United States. 24. Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom; National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust, London, United Kingdom; Mental Health Neuroscience Research Department, UCL Division of Psychiatry, University College London, United Kingdom. 25. Cognitive Genetics and Cognitive Therapy Group, Neuroimaging and Cognitive Genomics (NICOG) Centre and NCBES Galway Neuroscience Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland, Galway, Ireland. 26. Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland. 27. Genome Institute, Singapore. 28. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States. 29. The Mind Research Network, Albuquerque, NM, United States; Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, United States. 30. Department of Psychiatry, University of Minnesota, Minneapolis, MN, United States. 31. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Nathan S. Kline Institute for Psychiatric Research, Department of Psychiatry, New York University Langone Medical Center, New York, NY, United States. 32. Department of Epidemiology, Brown University, Providence, RI, United States. 33. Department of Medicine, Division of Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. 34. Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Massachusetts Mental Health Center Public Psychiatry Division, Beth Israel Deaconess Medical Center, Boston, MA, United States. 35. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States. 36. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Department of Psychiatry, Veterans Affairs Boston Healthcare System, Brockton, MA, United States; Laboratory of Applied Neuropsychology, University of Massachusetts, Boston, MA, United States. 37. Kimel Family Translational Imaging Genetics Laboratory, Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. 38. Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States; Department of Psychiatry, Brigham and Women's Hospital, Boston, MA, United States; Division of Psychiatric Genomics, Departments of Psychiatry and Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States. 39. Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom; Department of Psychology, Bilkent University, Bilkent, Ankara, Turkey; Department of Psychology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China. 40. Neuropsychiatric Genetics Research Group, Department of Psychiatry, Institute of Molecular Medicine, Trinity College Dublin, Dublin, Ireland; Cognitive Genetics and Cognitive Therapy Group, Neuroimaging and Cognitive Genomics (NICOG) Centre and NCBES Galway Neuroscience Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland, Galway, Ireland. 41. Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Department of Medicine, Division of Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States; Department of Medicine, Division of Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. 42. Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Harvard Medical School, Boston, MA, United States; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States. Electronic address: tpetryshen@mgh.harvard.edu.
Abstract
BACKGROUND: Schizophrenia has a large genetic component, and the pathways from genes to illness manifestation are beginning to be identified. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) Consortium aims to clarify the role of genetic variation in brain abnormalities underlying schizophrenia. This article describes the GENUS Consortium sample collection. METHODS: We identified existing samples collected for schizophrenia studies consisting of patients, controls, and/or individuals at familial high-risk (FHR) for schizophrenia. Samples had single nucleotide polymorphism (SNP) array data or genomic DNA, clinical and demographic data, and neuropsychological and/or brain magnetic resonance imaging (MRI) data. Data were subjected to quality control procedures at a central site. RESULTS: Sixteen research groups contributed data from 5199 psychosis patients, 4877 controls, and 725 FHR individuals. All participants have relevant demographic data and all patients have relevant clinical data. The sex ratio is 56.5% male and 43.5% female. Significant differences exist between diagnostic groups for premorbid and current IQ (both p<1×10-10). Data from a diversity of neuropsychological tests are available for 92% of participants, and 30% have structural MRI scans (half also have diffusion-weighted MRI scans). SNP data are available for 76% of participants. The ancestry composition is 70% European, 20% East Asian, 7% African, and 3% other. CONCLUSIONS: The Consortium is investigating the genetic contribution to brain phenotypes in a schizophrenia sample collection of >10,000 participants. The breadth of data across clinical, genetic, neuropsychological, and MRI modalities provides an important opportunity for elucidating the genetic basis of neural processes underlying schizophrenia.
BACKGROUND: Schizophrenia has a large genetic component, and the pathways from genes to illness manifestation are beginning to be identified. The Genetics of Endophenotypes of Neurofunction to Understand Schizophrenia (GENUS) Consortium aims to clarify the role of genetic variation in brain abnormalities underlying schizophrenia. This article describes the GENUS Consortium sample collection. METHODS: We identified existing samples collected for schizophrenia studies consisting of patients, controls, and/or individuals at familial high-risk (FHR) for schizophrenia. Samples had single nucleotide polymorphism (SNP) array data or genomic DNA, clinical and demographic data, and neuropsychological and/or brain magnetic resonance imaging (MRI) data. Data were subjected to quality control procedures at a central site. RESULTS: Sixteen research groups contributed data from 5199 psychosis patients, 4877 controls, and 725 FHR individuals. All participants have relevant demographic data and all patients have relevant clinical data. The sex ratio is 56.5% male and 43.5% female. Significant differences exist between diagnostic groups for premorbid and current IQ (both p<1×10-10). Data from a diversity of neuropsychological tests are available for 92% of participants, and 30% have structural MRI scans (half also have diffusion-weighted MRI scans). SNP data are available for 76% of participants. The ancestry composition is 70% European, 20% East Asian, 7% African, and 3% other. CONCLUSIONS: The Consortium is investigating the genetic contribution to brain phenotypes in a schizophrenia sample collection of >10,000 participants. The breadth of data across clinical, genetic, neuropsychological, and MRI modalities provides an important opportunity for elucidating the genetic basis of neural processes underlying schizophrenia.
Authors: David T Liebers; Mehdi Pirooznia; Fayaz Seiffudin; Katherine L Musliner; Peter P Zandi; Fernando S Goes Journal: Schizophr Bull Date: 2016-02-12 Impact factor: 9.306
Authors: Tian Ge; Thomas E Nichols; Phil H Lee; Avram J Holmes; Joshua L Roffman; Randy L Buckner; Mert R Sabuncu; Jordan W Smoller Journal: Proc Natl Acad Sci U S A Date: 2015-02-09 Impact factor: 11.205
Authors: Carol A Tamminga; Elena I Ivleva; Matcheri S Keshavan; Godfrey D Pearlson; Brett A Clementz; Bradley Witte; David W Morris; Jeffrey Bishop; Gunvant K Thaker; John A Sweeney Journal: Am J Psychiatry Date: 2013-11 Impact factor: 18.112
Authors: H W Thermenos; M S Keshavan; R J Juelich; E Molokotos; S Whitfield-Gabrieli; B K Brent; N Makris; L J Seidman Journal: Am J Med Genet B Neuropsychiatr Genet Date: 2013-10 Impact factor: 3.568
Authors: Christian R Marshall; Daniel P Howrigan; Daniele Merico; Bhooma Thiruvahindrapuram; Wenting Wu; Douglas S Greer; Danny Antaki; Aniket Shetty; Peter A Holmans; Dalila Pinto; Madhusudan Gujral; William M Brandler; Dheeraj Malhotra; Zhouzhi Wang; Karin V Fuentes Fajarado; Michelle S Maile; Stephan Ripke; Ingrid Agartz; Margot Albus; Madeline Alexander; Farooq Amin; Joshua Atkins; Silviu A Bacanu; Richard A Belliveau; Sarah E Bergen; Marcelo Bertalan; Elizabeth Bevilacqua; Tim B Bigdeli; Donald W Black; Richard Bruggeman; Nancy G Buccola; Randy L Buckner; Brendan Bulik-Sullivan; William Byerley; Wiepke Cahn; Guiqing Cai; Murray J Cairns; Dominique Campion; Rita M Cantor; Vaughan J Carr; Noa Carrera; Stanley V Catts; Kimberley D Chambert; Wei Cheng; C Robert Cloninger; David Cohen; Paul Cormican; Nick Craddock; Benedicto Crespo-Facorro; James J Crowley; David Curtis; Michael Davidson; Kenneth L Davis; Franziska Degenhardt; Jurgen Del Favero; Lynn E DeLisi; Dimitris Dikeos; Timothy Dinan; Srdjan Djurovic; Gary Donohoe; Elodie Drapeau; Jubao Duan; Frank Dudbridge; Peter Eichhammer; Johan Eriksson; Valentina Escott-Price; Laurent Essioux; Ayman H Fanous; Kai-How Farh; Martilias S Farrell; Josef Frank; Lude Franke; Robert Freedman; Nelson B Freimer; Joseph I Friedman; Andreas J Forstner; Menachem Fromer; Giulio Genovese; Lyudmila Georgieva; Elliot S Gershon; Ina Giegling; Paola Giusti-Rodríguez; Stephanie Godard; Jacqueline I Goldstein; Jacob Gratten; Lieuwe de Haan; Marian L Hamshere; Mark Hansen; Thomas Hansen; Vahram Haroutunian; Annette M Hartmann; Frans A Henskens; Stefan Herms; Joel N Hirschhorn; Per Hoffmann; Andrea Hofman; Hailiang Huang; Masashi Ikeda; Inge Joa; Anna K Kähler; René S Kahn; Luba Kalaydjieva; Juha Karjalainen; David Kavanagh; Matthew C Keller; Brian J Kelly; James L Kennedy; Yunjung Kim; James A Knowles; Bettina Konte; Claudine Laurent; Phil Lee; S Hong Lee; Sophie E Legge; Bernard Lerer; Deborah L Levy; Kung-Yee Liang; Jeffrey Lieberman; Jouko Lönnqvist; Carmel M Loughland; Patrik K E Magnusson; Brion S Maher; Wolfgang Maier; Jacques Mallet; Manuel Mattheisen; Morten Mattingsdal; Robert W McCarley; Colm McDonald; Andrew M McIntosh; Sandra Meier; Carin J Meijer; Ingrid Melle; Raquelle I Mesholam-Gately; Andres Metspalu; Patricia T Michie; Lili Milani; Vihra Milanova; Younes Mokrab; Derek W Morris; Bertram Müller-Myhsok; Kieran C Murphy; Robin M Murray; Inez Myin-Germeys; Igor Nenadic; Deborah A Nertney; Gerald Nestadt; Kristin K Nicodemus; Laura Nisenbaum; Annelie Nordin; Eadbhard O'Callaghan; Colm O'Dushlaine; Sang-Yun Oh; Ann Olincy; Line Olsen; F Anthony O'Neill; Jim Van Os; Christos Pantelis; George N Papadimitriou; Elena Parkhomenko; Michele T Pato; Tiina Paunio; Diana O Perkins; Tune H Pers; Olli Pietiläinen; Jonathan Pimm; Andrew J Pocklington; John Powell; Alkes Price; Ann E Pulver; Shaun M Purcell; Digby Quested; Henrik B Rasmussen; Abraham Reichenberg; Mark A Reimers; Alexander L Richards; Joshua L Roffman; Panos Roussos; Douglas M Ruderfer; Veikko Salomaa; Alan R Sanders; Adam Savitz; Ulrich Schall; Thomas G Schulze; Sibylle G Schwab; Edward M Scolnick; Rodney J Scott; Larry J Seidman; Jianxin Shi; Jeremy M Silverman; Jordan W Smoller; Erik Söderman; Chris C A Spencer; Eli A Stahl; Eric Strengman; Jana Strohmaier; T Scott Stroup; Jaana Suvisaari; Dragan M Svrakic; Jin P Szatkiewicz; Srinivas Thirumalai; Paul A Tooney; Juha Veijola; Peter M Visscher; John Waddington; Dermot Walsh; Bradley T Webb; Mark Weiser; Dieter B Wildenauer; Nigel M Williams; Stephanie Williams; Stephanie H Witt; Aaron R Wolen; Brandon K Wormley; Naomi R Wray; Jing Qin Wu; Clement C Zai; Rolf Adolfsson; Ole A Andreassen; Douglas H R Blackwood; Elvira Bramon; Joseph D Buxbaum; Sven Cichon; David A Collier; Aiden Corvin; Mark J Daly; Ariel Darvasi; Enrico Domenici; Tõnu Esko; Pablo V Gejman; Michael Gill; Hugh Gurling; Christina M Hultman; Nakao Iwata; Assen V Jablensky; Erik G Jönsson; Kenneth S Kendler; George Kirov; Jo Knight; Douglas F Levinson; Qingqin S Li; Steven A McCarroll; Andrew McQuillin; Jennifer L Moran; Bryan J Mowry; Markus M Nöthen; Roel A Ophoff; Michael J Owen; Aarno Palotie; Carlos N Pato; Tracey L Petryshen; Danielle Posthuma; Marcella Rietschel; Brien P Riley; Dan Rujescu; Pamela Sklar; David St Clair; James T R Walters; Thomas Werge; Patrick F Sullivan; Michael C O'Donovan; Stephen W Scherer; Benjamin M Neale; Jonathan Sebat Journal: Nat Genet Date: 2016-11-21 Impact factor: 38.330
Authors: G Davies; N Armstrong; J C Bis; J Bressler; V Chouraki; S Giddaluru; E Hofer; C A Ibrahim-Verbaas; M Kirin; J Lahti; S J van der Lee; S Le Hellard; T Liu; R E Marioni; C Oldmeadow; I Postmus; A V Smith; J A Smith; A Thalamuthu; R Thomson; V Vitart; J Wang; L Yu; L Zgaga; W Zhao; R Boxall; S E Harris; W D Hill; D C Liewald; M Luciano; H Adams; D Ames; N Amin; P Amouyel; A A Assareh; R Au; J T Becker; A Beiser; C Berr; L Bertram; E Boerwinkle; B M Buckley; H Campbell; J Corley; P L De Jager; C Dufouil; J G Eriksson; T Espeseth; J D Faul; I Ford; R F Gottesman; M E Griswold; V Gudnason; T B Harris; G Heiss; A Hofman; E G Holliday; J Huffman; S L R Kardia; N Kochan; D S Knopman; J B Kwok; J-C Lambert; T Lee; G Li; S-C Li; M Loitfelder; O L Lopez; A J Lundervold; A Lundqvist; K A Mather; S S Mirza; L Nyberg; B A Oostra; A Palotie; G Papenberg; A Pattie; K Petrovic; O Polasek; B M Psaty; P Redmond; S Reppermund; J I Rotter; H Schmidt; M Schuur; P W Schofield; R J Scott; V M Steen; D J Stott; J C van Swieten; K D Taylor; J Trollor; S Trompet; A G Uitterlinden; G Weinstein; E Widen; B G Windham; J W Jukema; A F Wright; M J Wright; Q Yang; H Amieva; J R Attia; D A Bennett; H Brodaty; A J M de Craen; C Hayward; M A Ikram; U Lindenberger; L-G Nilsson; D J Porteous; K Räikkönen; I Reinvang; I Rudan; P S Sachdev; R Schmidt; P R Schofield; V Srikanth; J M Starr; S T Turner; D R Weir; J F Wilson; C van Duijn; L Launer; A L Fitzpatrick; S Seshadri; T H Mosley; I J Deary Journal: Mol Psychiatry Date: 2015-02-03 Impact factor: 15.992
Authors: Adam Auton; Lisa D Brooks; Richard M Durbin; Erik P Garrison; Hyun Min Kang; Jan O Korbel; Jonathan L Marchini; Shane McCarthy; Gil A McVean; Gonçalo R Abecasis Journal: Nature Date: 2015-10-01 Impact factor: 49.962
Authors: Stephan Ripke; Colm O'Dushlaine; Kimberly Chambert; Jennifer L Moran; Anna K Kähler; Susanne Akterin; Sarah E Bergen; Ann L Collins; James J Crowley; Menachem Fromer; Yunjung Kim; Sang Hong Lee; Patrik K E Magnusson; Nick Sanchez; Eli A Stahl; Stephanie Williams; Naomi R Wray; Kai Xia; Francesco Bettella; Anders D Borglum; Brendan K Bulik-Sullivan; Paul Cormican; Nick Craddock; Christiaan de Leeuw; Naser Durmishi; Michael Gill; Vera Golimbet; Marian L Hamshere; Peter Holmans; David M Hougaard; Kenneth S Kendler; Kuang Lin; Derek W Morris; Ole Mors; Preben B Mortensen; Benjamin M Neale; Francis A O'Neill; Michael J Owen; Milica Pejovic Milovancevic; Danielle Posthuma; John Powell; Alexander L Richards; Brien P Riley; Douglas Ruderfer; Dan Rujescu; Engilbert Sigurdsson; Teimuraz Silagadze; August B Smit; Hreinn Stefansson; Stacy Steinberg; Jaana Suvisaari; Sarah Tosato; Matthijs Verhage; James T Walters; Douglas F Levinson; Pablo V Gejman; Kenneth S Kendler; Claudine Laurent; Bryan J Mowry; Michael C O'Donovan; Michael J Owen; Ann E Pulver; Brien P Riley; Sibylle G Schwab; Dieter B Wildenauer; Frank Dudbridge; Peter Holmans; Jianxin Shi; Margot Albus; Madeline Alexander; Dominique Campion; David Cohen; Dimitris Dikeos; Jubao Duan; Peter Eichhammer; Stephanie Godard; Mark Hansen; F Bernard Lerer; Kung-Yee Liang; Wolfgang Maier; Jacques Mallet; Deborah A Nertney; Gerald Nestadt; Nadine Norton; Francis A O'Neill; George N Papadimitriou; Robert Ribble; Alan R Sanders; Jeremy M Silverman; Dermot Walsh; Nigel M Williams; Brandon Wormley; Maria J Arranz; Steven Bakker; Stephan Bender; Elvira Bramon; David Collier; Benedicto Crespo-Facorro; Jeremy Hall; Conrad Iyegbe; Assen Jablensky; Rene S Kahn; Luba Kalaydjieva; Stephen Lawrie; Cathryn M Lewis; Kuang Lin; Don H Linszen; Ignacio Mata; Andrew McIntosh; Robin M Murray; Roel A Ophoff; John Powell; Dan Rujescu; Jim Van Os; Muriel Walshe; Matthias Weisbrod; Durk Wiersma; Peter Donnelly; Ines Barroso; Jenefer M Blackwell; Elvira Bramon; Matthew A Brown; Juan P Casas; Aiden P Corvin; Panos Deloukas; Audrey Duncanson; Janusz Jankowski; Hugh S Markus; Christopher G Mathew; Colin N A Palmer; Robert Plomin; Anna Rautanen; Stephen J Sawcer; Richard C Trembath; Ananth C Viswanathan; Nicholas W Wood; Chris C A Spencer; Gavin Band; Céline Bellenguez; Colin Freeman; Garrett Hellenthal; Eleni Giannoulatou; Matti Pirinen; Richard D Pearson; Amy Strange; Zhan Su; Damjan Vukcevic; Peter Donnelly; Cordelia Langford; Sarah E Hunt; Sarah Edkins; Rhian Gwilliam; Hannah Blackburn; Suzannah J Bumpstead; Serge Dronov; Matthew Gillman; Emma Gray; Naomi Hammond; Alagurevathi Jayakumar; Owen T McCann; Jennifer Liddle; Simon C Potter; Radhi Ravindrarajah; Michelle Ricketts; Avazeh Tashakkori-Ghanbaria; Matthew J Waller; Paul Weston; Sara Widaa; Pamela Whittaker; Ines Barroso; Panos Deloukas; Christopher G Mathew; Jenefer M Blackwell; Matthew A Brown; Aiden P Corvin; Mark I McCarthy; Chris C A Spencer; Elvira Bramon; Aiden P Corvin; Michael C O'Donovan; Kari Stefansson; Edward Scolnick; Shaun Purcell; Steven A McCarroll; Pamela Sklar; Christina M Hultman; Patrick F Sullivan Journal: Nat Genet Date: 2013-08-25 Impact factor: 38.330
Authors: Timothea Toulopoulou; Xiaowei Zhang; Stacey Cherny; Dwight Dickinson; Karen F Berman; Richard E Straub; Pak Sham; Daniel R Weinberger Journal: Brain Date: 2019-02-01 Impact factor: 13.501
Authors: Tonya M Gilbert; Nicole R Zürcher; Christine J Wu; Anisha Bhanot; Baileigh G Hightower; Minhae Kim; Daniel S Albrecht; Hsiao-Ying Wey; Frederick A Schroeder; Anais Rodriguez-Thompson; Thomas M Morin; Kamber L Hart; Amelia M Pellegrini; Misha M Riley; Changning Wang; Steven M Stufflebeam; Stephen J Haggarty; Daphne J Holt; Marco L Loggia; Roy H Perlis; Hannah E Brown; Joshua L Roffman; Jacob M Hooker Journal: J Clin Invest Date: 2018-12-10 Impact factor: 14.808
Authors: Bhim M Adhikari; L Elliot Hong; Hemalatha Sampath; Joshua Chiappelli; Neda Jahanshad; Paul M Thompson; Laura M Rowland; Vince D Calhoun; Xiaoming Du; Shuo Chen; Peter Kochunov Journal: Hum Brain Mapp Date: 2019-07-16 Impact factor: 5.038
Authors: Suheyla Cetin-Karayumak; Maria A Di Biase; Natalia Chunga; Benjamin Reid; Nathaniel Somes; Amanda E Lyall; Sinead Kelly; Bengisu Solgun; Ofer Pasternak; Mark Vangel; Godfrey Pearlson; Carol Tamminga; John A Sweeney; Brett Clementz; David Schretlen; Petra Verena Viher; Katharina Stegmayer; Sebastian Walther; Jungsun Lee; Tim Crow; Anthony James; Aristotle Voineskos; Robert W Buchanan; Philip R Szeszko; Anil K Malhotra; Rachal Hegde; Robert McCarley; Matcheri Keshavan; Martha Shenton; Yogesh Rathi; Marek Kubicki Journal: Mol Psychiatry Date: 2019-09-11 Impact factor: 13.437
Authors: Lorenzo Caciagli; Britta Wandschneider; Fenglai Xiao; Christian Vollmar; Maria Centeno; Sjoerd B Vos; Karin Trimmel; Meneka K Sidhu; Pamela J Thompson; Gavin P Winston; John S Duncan; Matthias J Koepp Journal: Brain Date: 2019-09-01 Impact factor: 13.501
Authors: Lorenzo Caciagli; Britta Wandschneider; Maria Centeno; Christian Vollmar; Sjoerd B Vos; Karin Trimmel; Lili Long; Fenglai Xiao; Alexander J Lowe; Meneka K Sidhu; Pamela J Thompson; Gavin P Winston; John S Duncan; Matthias J Koepp Journal: Epilepsia Date: 2020-06-25 Impact factor: 6.740
Authors: Maria B Misiura; J Christina Howell; Junjie Wu; Deqiang Qiu; Monica W Parker; Jessica A Turner; William T Hu Journal: Transl Neurodegener Date: 2020-02-19 Impact factor: 8.014
Authors: Johan H Thygesen; Amelia Presman; Jasmine Harju-Seppänen; Haritz Irizar; Rebecca Jones; Karoline Kuchenbaecker; Kuang Lin; Behrooz Z Alizadeh; Isabelle Austin-Zimmerman; Agna Bartels-Velthuis; Anjali Bhat; Richard Bruggeman; Wiepke Cahn; Stella Calafato; Benedicto Crespo-Facorro; Liewe de Haan; Sonja M C de Zwarte; Marta Di Forti; Álvaro Díez-Revuelta; Jeremy Hall; Mei-Hua Hall; Conrad Iyegbe; Assen Jablensky; Rene Kahn; Luba Kalaydjieva; Eugenia Kravariti; Stephen Lawrie; Jurjen J Luykx; Igancio Mata; Colm McDonald; Andrew M McIntosh; Andrew McQuillin; Rebecca Muir; Roel Ophoff; Marco Picchioni; Diana P Prata; Siri Ranlund; Dan Rujescu; Bart P F Rutten; Katja Schulze; Madiha Shaikh; Frederike Schirmbeck; Claudia J P Simons; Timothea Toulopoulou; Therese van Amelsvoort; Neeltje van Haren; Jim van Os; Ruud van Winkel; Evangelos Vassos; Muriel Walshe; Matthias Weisbrod; Eirini Zartaloudi; Vaughan Bell; John Powell; Cathryn M Lewis; Robin M Murray; Elvira Bramon Journal: Mol Psychiatry Date: 2020-07-27 Impact factor: 15.992