Literature DB >> 28979658

RADIATION THERAPY for the Adjunctive Treatment of Surgically Excised Keloids: A Review.

Nikoo Cheraghi1, Armand Cognetta1, David Goldberg1.   

Abstract

BACKGROUND: Radiotherapy has been used historically to treat a wide variety of dermatologie conditions, including nonmelanoma skin cancers, lymphomas, and inflammatory skin conditions. Recently, radiotherapy has been used increasingly as a valuable tool in the postsurgical treatment of large or recalcitrant keloids.
OBJECTIVE: The objective of this review was to explore the use of radiation therapy as an adjuvant to surgically excised keloids.
DESIGN: A PubMed search of all published English literature regarding the applications of radiotherapy for the treatment of keloids was performed using a combination of keywords including radiation, radiotherapy, brachytherapy, electron beam, superficial radiation, orthovoltage radiation, and keloid. The results were analyzed and collated.
RESULTS: A comprehensive review of radiotherapy for the adjuvant treatment of keloids was outlined.
CONCLUSION: Radiotherapy appears useful as an adjuvant therapy to surgically excised keloids. Dermatologists should be well versed in radiotherapy to provide optimal care for patients with recalcitrant keloids.

Entities:  

Keywords:  Radiotherapy; brachytherapy; electron beam; keloid; orthovoltage radiation; superficial radiation

Year:  2017        PMID: 28979658      PMCID: PMC5605209     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  25 in total

Review 1.  International clinical recommendations on scar management.

Authors:  Thomas A Mustoe; Rodney D Cooter; Michael H Gold; F D Richard Hobbs; Albert-Adrien Ramelet; Peter G Shakespeare; Maurizio Stella; Luc Téot; Fiona M Wood; Ulrich E Ziegler
Journal:  Plast Reconstr Surg       Date:  2002-08       Impact factor: 4.730

2.  Radiotherapy of non-malignant disorders: where do we stand?

Authors:  Jan Willem Leer; Paul van Houtte; Heinrich Seegenschmiedt
Journal:  Radiother Oncol       Date:  2007-05-08       Impact factor: 6.280

3.  Dose-response relationship and dose optimization in radiotherapy of postoperative keloids.

Authors:  Takashi Sakamoto; Natsuo Oya; Keiko Shibuya; Yasushi Nagata; Masahiro Hiraoka
Journal:  Radiother Oncol       Date:  2009-02-07       Impact factor: 6.280

4.  Forty-five cases of chest keloids treated with subcutaneous super-tension-reduction suture combined with postoperative electron-beam irradiation.

Authors:  Lian-Zhao Wang; Jin-Ping Ding; Ming-Yong Yang; Bo Chen
Journal:  Dermatol Surg       Date:  2014-12       Impact factor: 3.398

Review 5.  Updated international clinical recommendations on scar management: part 1--evaluating the evidence.

Authors:  Michael H Gold; Brian Berman; Matteo Tretti Clementoni; Gerd G Gauglitz; Foad Nahai; Crystal Murcia
Journal:  Dermatol Surg       Date:  2014-08       Impact factor: 3.398

6.  Surgical excision and immediate postoperative radiotherapy versus cryotherapy and intralesional steroids in the management of keloids: a prospective clinical trial.

Authors:  Maryam Emad; Shapour Omidvari; Ladan Dastgheib; Afshin Mortazavi; Haleh Ghaem
Journal:  Med Princ Pract       Date:  2010-07-14       Impact factor: 1.927

Review 7.  Is radiation therapy for keloids acceptable? The risk of radiation-induced carcinogenesis.

Authors:  Rei Ogawa; Sumiko Yoshitatsu; Ken Yoshida; Tsuguhiro Miyashita
Journal:  Plast Reconstr Surg       Date:  2009-10       Impact factor: 4.730

8.  Keloids treated with excision followed by radiation therapy.

Authors:  D I Klumpar; J C Murray; M Anscher
Journal:  J Am Acad Dermatol       Date:  1994-08       Impact factor: 11.527

9.  Hypofractionated electron-beam radiation therapy for keloids: retrospective study of 568 cases with 834 lesions.

Authors:  Jie Shen; Xin Lian; Yuliang Sun; Xiaojun Wang; Ke Hu; Xiaorong Hou; Shuai Sun; Junfang Yan; Lang Yu; Xiansong Sun; Wenbo Li; Xinhai Wang; Qiu Guan; Tingtian Pang; Fuquan Zhang
Journal:  J Radiat Res       Date:  2015-07-28       Impact factor: 2.724

10.  Adjuvant single-fraction radiotherapy is safe and effective for intractable keloids.

Authors:  Changhoon Song; Hong-Gyun Wu; Hak Chang; Il Han Kim; Sung W Ha
Journal:  J Radiat Res       Date:  2014-05-06       Impact factor: 2.724

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  11 in total

Review 1.  A Retrospective Registry Study Evaluating the Long-Term Efficacy and Safety of Superficial Radiation Therapy Following Excision of Keloid Scars.

Authors:  Brian Berman; Mark S Nestor; Michael H Gold; David J Goldberg; Eduardo T Weiss; Isabelle Raymond
Journal:  J Clin Aesthet Dermatol       Date:  2020-10-01

2.  Consensus Guidelines on the Use of Superficial Radiation Therapy for Treating Nonmelanoma Skin Cancers and Keloids.

Authors:  Mark S Nestor; Brian Berman; David Goldberg; Armand B Cognetta; Michael Gold; William Roth; Clay J Cockerell; Brad Glick
Journal:  J Clin Aesthet Dermatol       Date:  2019-02-01

3.  Scar-centered dilation in the treatment of large keloids.

Authors:  Min Wu; Jie-Yu Gu; Ran Duan; Bo-Xuan Wei; Feng Xie
Journal:  World J Clin Cases       Date:  2022-06-26       Impact factor: 1.534

4.  Adjuvant intensity-modulated radiotherapy improves outcomes for resected complex keloids.

Authors:  Evelyn O Ilori; Shauna R Campbell; Timothy D Smile; Lanae Keller; Nikhil P Joshi; Neil M Woody; Shlomo A Koyfman
Journal:  JAAD Case Rep       Date:  2022-05-28

Review 5.  Keloids: Current and emerging therapies.

Authors:  Nkemcho Ojeh; Ambadasu Bharatha; Uma Gaur; Andrew LeRoy Forde
Journal:  Scars Burn Heal       Date:  2020-08-10

6.  Surface brachytherapy in the treatment of keloid scars in Mexico.

Authors:  Yicel Bautista Hernandez; Michelle Aline Villavicencio Queijero; Abril Antonia Quezada Bautista; Azcary Vazquez Tinajero
Journal:  Rep Pract Oncol Radiother       Date:  2019-12-24

7.  The outcome of postoperative radiation therapy following plastic surgical resection of recurrent ear keloid: a single institution experience.

Authors:  Reham Mohamed; Abosaleh Abosaleh Elawadi; Reham Al-Gendi; Safa Al-Mohsen; Shabeer Wani; Ahmed Wafa
Journal:  J Egypt Natl Canc Inst       Date:  2022-01-24

8.  Keloid treatment: what about adjuvant radiotherapy?

Authors:  Ilias G Petrou; Kheeldass Jugun; Eva Meia Rüegg; Thomas Zilli; Ali Modarressi; Brigitte Pittet-Cuénod
Journal:  Clin Cosmet Investig Dermatol       Date:  2019-05-03

9.  Surgical Excision of Keloids Followed by In-office Superficial Radiation Therapy: Prospective Study Examining Clinical Outcomes.

Authors:  Michael E Jones; Christine A Ganzer; Deanne Bennett; Andrea Finizio
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-05-03

10.  A hesitated approach: primary radiotherapy for keloids-a case series.

Authors:  Sezin Yuce Sari; Melek Tugce Yilmaz; Gozde Yazici; Hakan Uzun; Fazli Yagiz Yedekci; Gokhan Ozyigit
Journal:  Strahlenther Onkol       Date:  2021-01-04       Impact factor: 3.621

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