David Martinez-Gomez1, Pilar Guallar-Castillon2,3, Sara Higueras-Fresnillo1, Esther Garcia-Esquinas2, Esther Lopez-Garcia2,3, Stefania Bandinelli4, Fernando Rodríguez-Artalejo2,3. 1. Department of Physical Education, Sport and Human Movement, Faculty of Teacher Training and Education, Universidad Autónoma de Madrid, Spain. 2. Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, CIBER of Epidemiology and Public Health (CIBERESP), Spain. 3. IMDEA-Food Institute and CEI UAM+CSIC, Madrid, Spain. 4. Geriatric Unit, Local Health Tuscany Center, Florence, Italy.
Abstract
Background: Regular physical activity (PA) has been shown to protect against disability onset but, once the disability is present, it is unclear if PA might attenuate its harmful health consequences. Thus, we examined if mortality risk associated with physical disability can be offset by PA among older adults. Methods: We used data from a cohort of 3,752 individuals representative of the noninstitutionalized population aged 60 years and older in Spain. In 2000-2001, participants self-reported both PA levels (inactive, occasionally, monthly, weekly) and five physical disabilities (agility, mobility, global daily activities, instrumental activities of daily living, and self-care). Individuals were prospectively followed through 2014 to assess incident deaths. Results: The mean follow-up was 10.8 years, with a total of 1,727 deaths, 638 of them due to cardiovascular disease (CVD). All disability types were associated with higher total and CVD mortality. Being physically active (ie, doing any PA) was associated with a statistically significant 26%-37% and 35%-50% lower risk of total and CVD death, respectively, across types of disability. As compared with those being physically active and without disability, those who were inactive and had a disability showed the highest mortality risk from total (hazard ratios from 1.52 to 1.90 across disabilities, all p < .05) and from CVD (hazard ratios from 1.99 to 2.24 across disabilities, all p < .05). Total and CVD mortality risk was similar in physically active participants with disabilities and in inactive individuals without disability. Conclusions: In older adults, PA could attenuate the increased risk of mortality associated with physical disability.
Background: Regular physical activity (PA) has been shown to protect against disability onset but, once the disability is present, it is unclear if PA might attenuate its harmful health consequences. Thus, we examined if mortality risk associated with physical disability can be offset by PA among older adults. Methods: We used data from a cohort of 3,752 individuals representative of the noninstitutionalized population aged 60 years and older in Spain. In 2000-2001, participants self-reported both PA levels (inactive, occasionally, monthly, weekly) and five physical disabilities (agility, mobility, global daily activities, instrumental activities of daily living, and self-care). Individuals were prospectively followed through 2014 to assess incident deaths. Results: The mean follow-up was 10.8 years, with a total of 1,727 deaths, 638 of them due to cardiovascular disease (CVD). All disability types were associated with higher total and CVD mortality. Being physically active (ie, doing any PA) was associated with a statistically significant 26%-37% and 35%-50% lower risk of total and CVD death, respectively, across types of disability. As compared with those being physically active and without disability, those who were inactive and had a disability showed the highest mortality risk from total (hazard ratios from 1.52 to 1.90 across disabilities, all p < .05) and from CVD (hazard ratios from 1.99 to 2.24 across disabilities, all p < .05). Total and CVD mortality risk was similar in physically active participants with disabilities and in inactive individuals without disability. Conclusions: In older adults, PA could attenuate the increased risk of mortality associated with physical disability.
Authors: Petros Barmpas; Sotiris Tasoulis; Aristidis G Vrahatis; Spiros V Georgakopoulos; Panagiotis Anagnostou; Matthew Prina; José Luis Ayuso-Mateos; Jerome Bickenbach; Ivet Bayes; Martin Bobak; Francisco Félix Caballero; Somnath Chatterji; Laia Egea-Cortés; Esther García-Esquinas; Matilde Leonardi; Seppo Koskinen; Ilona Koupil; Andrzej Paja K; Martin Prince; Warren Sanderson; Sergei Scherbov; Abdonas Tamosiunas; Aleksander Galas; Josep Maria Haro; Albert Sanchez-Niubo; Vassilis P Plagianakos; Demosthenes Panagiotakos Journal: Health Inf Sci Syst Date: 2022-04-18
Authors: Sara Higueras-Fresnillo; Verónica Cabanas-Sánchez; Esther García-Esquinas; Fernando Rodríguez-Artalejo; David Martinez-Gomez Journal: Qual Life Res Date: 2018-09-11 Impact factor: 4.147
Authors: Zhangyu Wang; Kaiwang Cui; Ruixue Song; Xuerui Li; Xiuying Qi; Aron S Buchman; David A Bennett; Weili Xu Journal: Front Med (Lausanne) Date: 2022-04-26
Authors: Juan Luis Sanchez-Sanchez; Mikel Izquierdo; Jose Antonio Carnicero-Carreño; Fransico José García-García; Leocadio Rodríguez-Mañas Journal: J Cachexia Sarcopenia Muscle Date: 2020-03-12 Impact factor: 12.910