| Literature DB >> 28975875 |
Karri Silventoinen1, Aline Jelenkovic1, Antti Latvala2, Reijo Sund1, Yoshie Yokoyama3, Vilhelmina Ullemar4, Catarina Almqvist4, Catherine A Derom5, Robert F Vlietinck5, Ruth J F Loos6, Christian Kandler7, Chika Honda8, Fujio Inui8, Yoshinori Iwatani8, Mikio Watanabe8, Esther Rebato9, Maria A Stazi10, Corrado Fagnani10, Sonia Brescianini10, Yoon-Mi Hur11, Hoe-Uk Jeong11, Tessa L Cutler12, John L Hopper12, Andreas Busjahn13, Kimberly J Saudino14, Fuling Ji15, Feng Ning15, Zengchang Pang15, Richard J Rose16, Markku Koskenvuo2, Kauko Heikkilä2, Wendy Cozen17, Amie E Hwang17, Thomas M Mack17, Sisira H Siribaddana18, Matthew Hotopf19, Athula Sumathipala18, Fruhling Rijsdijk20, Joohon Sung21, Jina Kim21, Jooyeon Lee21, Sooji Lee21, Tracy L Nelson22, Keith E Whitfield23, Qihua Tan24, Dongfeng Zhang25, Clare H Llewellyn26, Abigail Fisher26, S Alexandra Burt27, Kelly L Klump27, Ariel Knafo-Noam28, David Mankuta29, Lior Abramson28, Sarah E Medland30, Nicholas G Martin30, Grant W Montgomery31, Patrik K E Magnusson4, Nancy L Pedersen4, Anna K Dahl Aslan4, Robin P Corley32, Brooke M Huibregtse32, Sevgi Y Öncel33, Fazil Aliev34, Robert F Krueger35, Matt McGue35, Shandell Pahlen35, Gonneke Willemsen36, Meike Bartels36, Catharina E M van Beijsterveldt36, Judy L Silberg37, Lindon J Eaves37, Hermine H Maes38, Jennifer R Harris39, Ingunn Brandt39, Thomas S Nilsen39, Finn Rasmussen40, Per Tynelius41, Laura A Baker42, Catherine Tuvblad42, Juan R Ordoñana43, Juan F Sánchez-Romera43, Lucia Colodro-Conde43, Margaret Gatz4, David A Butler44, Paul Lichtenstein4, Jack H Goldberg45, K Paige Harden46, Elliot M Tucker-Drob46, Glen E Duncan47, Dedra Buchwald47, Adam D Tarnoki48, David L Tarnoki48, Carol E Franz49, William S Kremen49, Michael J Lyons50, José A Maia51, Duarte L Freitas52, Eric Turkheimer53, Thorkild I A Sørensen54, Dorret I Boomsma36, Jaakko Kaprio2.
Abstract
Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences made from twin studies in general. We analyzed whether there were differences in individual, maternal and paternal education between MZ and DZ twins in a large pooled dataset. Information was gathered on individual education for 218,362 adult twins from 27 twin cohorts (53% females; 39% MZ twins), and on maternal and paternal education for 147,315 and 143,056 twins respectively, from 28 twin cohorts (52% females; 38% MZ twins). Together, we had information on individual or parental education from 42 twin cohorts representing 19 countries. The original education classifications were transformed to education years and analyzed using linear regression models. Overall, MZ males had 0.26 (95% CI [0.21, 0.31]) years and MZ females 0.17 (95% CI [0.12, 0.21]) years longer education than DZ twins. The zygosity difference became smaller in more recent birth cohorts for both males and females. Parental education was somewhat longer for fathers of DZ twins in cohorts born in 1990-1999 (0.16 years, 95% CI [0.08, 0.25]) and 2000 or later (0.11 years, 95% CI [0.00, 0.22]), compared with fathers of MZ twins. The results show that the years of both individual and parental education are largely similar in MZ and DZ twins. We suggest that the socio-economic differences between MZ and DZ twins are so small that inferences based upon genetic modeling of twin data are not affected.Entities:
Keywords: education; parental education; twins; zygosity
Mesh：
Year: 2017 PMID： 28975875 PMCID： PMC5969906 DOI： 10.1017/thg.2017.49
Source DB: PubMed Journal: Twin Res Hum Genet ISSN： 1832-4274 Impact factor: 1.587