Javier Quintero1,2, Isabel Morales3, Rosa Vera2, Pilar Zuluaga2, Alberto Fernández2,4. 1. 1 Hospital Universitario Infanta Leonor, Madrid, Spain. 2. 2 Complutense University of Madrid, Spain. 3. 3 Psikids Pozuelo, Madrid, Spain. 4. 4 Technical University of Madrid, Spain.
Abstract
OBJECTIVE: In this multicenter, cross-sectional study, we aimed to investigate the quality of life (QoL) and the neuropsychological and clinical characteristics of adults with ADHD with different developmental pathways. METHOD: Our study sample included 25 control (healthy) participants, 31 patients with newly diagnosed ADHD without comorbidities (ADHD-C-D), 31 with newly diagnosed ADHD with comorbidities (ADHD+C-D), and 29 with previously diagnosed ADHD with comorbidities (ADHD+C+D). RESULTS: Compared with controls, ADHDs had little differences in the attentional performance but showed higher impulsivity, more severe symptoms of depression and anxiety, and lower QoL. The ADHD+C-D group showed more severe symptoms of depression and anxiety than the ADHD+C+D group ( p = .037 and p = .008, respectively), and poorer QoL in the psychological health sphere ( p = .003). CONCLUSION: Differences between ADHD and control subjects were particularly remarkable in mood symptoms and QoL. Previous diagnosis might have a positive impact on mood symptoms and QoL in ADHD adults.
OBJECTIVE: In this multicenter, cross-sectional study, we aimed to investigate the quality of life (QoL) and the neuropsychological and clinical characteristics of adults with ADHD with different developmental pathways. METHOD: Our study sample included 25 control (healthy) participants, 31 patients with newly diagnosed ADHD without comorbidities (ADHD-C-D), 31 with newly diagnosed ADHD with comorbidities (ADHD+C-D), and 29 with previously diagnosed ADHD with comorbidities (ADHD+C+D). RESULTS: Compared with controls, ADHDs had little differences in the attentional performance but showed higher impulsivity, more severe symptoms of depression and anxiety, and lower QoL. The ADHD+C-D group showed more severe symptoms of depression and anxiety than the ADHD+C+D group ( p = .037 and p = .008, respectively), and poorer QoL in the psychological health sphere ( p = .003). CONCLUSION: Differences between ADHD and control subjects were particularly remarkable in mood symptoms and QoL. Previous diagnosis might have a positive impact on mood symptoms and QoL in ADHD adults.
Entities:
Keywords:
ADHD; adult ADD; comorbidity; developmental pathways; quality of life
Authors: Jesse Elliott; Amy Johnston; Don Husereau; Shannon E Kelly; Caroline Eagles; Alice Charach; Shu-Ching Hsieh; Zemin Bai; Alomgir Hossain; Becky Skidmore; Eva Tsakonas; Dagmara Chojecki; Muhammad Mamdani; George A Wells Journal: PLoS One Date: 2020-10-21 Impact factor: 3.240