Literature DB >> 28971335

Digital Waveform Technology and the Next Generation of Mass Spectrometers.

Nathan M Hoffman1, Zachary P Gotlib1, Bojana Opačić1, Adam P Huntley1, Ashley M Moon1, Katherine E G Donahoe1, Gregory F Brabeck1, Peter T A Reilly2.   

Abstract

Ion traps and guides are integral parts of current commercial mass spectrometers. They are currently operated with sinusoidal waveform technology that has been developed over many years. Recently, digital waveform technology has begun to emerge and promises to supplant its older cousin because it presents new capabilities that result from the ability to instantaneously switch the frequency and duty cycle of the waveforms. This manuscript examines these capabilities and reveals their uses and effects on instrumentation. Graphical Abstract ᅟ.

Keywords:  Digital waveform technology; Ion traps and guides; Stability diagrams

Year:  2017        PMID： 28971335     DOI： 10.1007/s13361-017-1807-8

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN： 1044-0305            Impact factor:   3.109


  15 in total

1.  Charge reduction electrospray mass spectrometry.

Authors:  M Scalf; M S Westphall; L M Smith
Journal:  Anal Chem       Date:  2000-01-01       Impact factor: 6.986

2.  Matrix methods for the calculation of stability diagrams in quadrupole mass spectrometry.

Authors:  N V Konenkov; M Sudakov; D J Douglas
Journal:  J Am Soc Mass Spectrom       Date:  2002-06       Impact factor: 3.109

3.  Improved ion extraction from a linear octopole ion trap: SIMION analysis and experimental demonstration.

Authors:  Bruce E Wilcox; Christopher L Hendrickson; Alan G Marshall
Journal:  J Am Soc Mass Spectrom       Date:  2002-11       Impact factor: 3.109

4.  A digital ion trap mass spectrometer coupled with atmospheric pressure ion sources.

Authors:  Li Ding; Michael Sudakov; Francesco L Brancia; Roger Giles; Sumio Kumashiro
Journal:  J Mass Spectrom       Date:  2004-05       Impact factor: 1.982

Review 5.  Orbitrap mass spectrometry: instrumentation, ion motion and applications.

Authors:  Richard H Perry; R Graham Cooks; Robert J Noll
Journal:  Mass Spectrom Rev       Date:  2008 Nov-Dec       Impact factor: 10.946

Review 6.  Fourier transform ion cyclotron resonance mass spectrometry: a primer.

Authors:  A G Marshall; C L Hendrickson; G S Jackson
Journal:  Mass Spectrom Rev       Date:  1998 Jan-Feb       Impact factor: 10.946

7.  Simulation of Duty Cycle-Based Trapping and Ejection of Massive Ions Using Linear Digital Quadrupoles: the Enabling Technology for High Resolution Time-of-Flight Mass Spectrometry in the Ultra High Mass Range.

Authors:  Jeonghoon Lee; Maxwell A Marino; Hideya Koizumi; Peter T A Reilly
Journal:  Int J Mass Spectrom       Date:  2011-06-15       Impact factor: 1.986

8.  High-resolution ultra-high mass spectrometry: increasing the m/z range of protein analysis.

Authors:  Huijuan Chen; Jeonghoon Lee; Peter T A Reilly
Journal:  Proteomics       Date:  2012-08-29       Impact factor: 3.984

9.  Development of MS(n) in digitally operated linear ion guides.

Authors:  Gregory F Brabeck; Huijuan Chen; Nathan M Hoffman; Liang Wang; Peter T A Reilly
Journal:  Anal Chem       Date:  2014-07-08       Impact factor: 6.986

10.  High resolution time-of-flight mass analysis of the entire range of intact singly-charged proteins.

Authors:  Jeonghoon Lee; Huijuan Chen; Tiancheng Liu; Clifford E Berkman; Peter T A Reilly
Journal:  Anal Chem       Date:  2011-11-17       Impact factor: 6.986
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  4 in total

1.  Ion trap operational modes for ion/ion reactions yielding high mass-to-charge product ions.

Authors:  Kenneth W Lee; Gregory S Eakins; Mark S Carlsen; Scott A McLuckey
Journal:  Int J Mass Spectrom       Date:  2020-02-21       Impact factor: 1.986

2.  Using Digital Waveforms to Mitigate Solvent Clustering During Mass Filter Analysis of Proteins.

Authors:  Bojana Opačić; Nathan M Hoffman; Zachary P Gotlib; Brian H Clowers; Peter T A Reilly
Journal:  J Am Soc Mass Spectrom       Date:  2018-07-09       Impact factor: 3.109

3.  Increasing the Upper Mass/Charge Limit of a Quadrupole Ion Trap for Ion/Ion Reaction Product Analysis via Waveform Switching.

Authors:  Kenneth W Lee; Gregory S Eakins; Mark S Carlsen; Scott A McLuckey
Journal:  J Am Soc Mass Spectrom       Date:  2019-03-14       Impact factor: 3.109

4.  Implementing Digital-Waveform Technology for Extended m/z Range Operation on a Native Dual-Quadrupole FT-IM-Orbitrap Mass Spectrometer.

Authors:  Jacob W McCabe; Benjamin J Jones; Thomas E Walker; Robert L Schrader; Adam P Huntley; Jixing Lyu; Nathan M Hoffman; Gordon A Anderson; Peter T A Reilly; Arthur Laganowsky; Vicki H Wysocki; David H Russell
Journal:  J Am Soc Mass Spectrom       Date:  2021-11-19       Impact factor: 3.262
  4 in total

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