Michael Goldenshluger1, Ariela Goldenshluger2, Lital Keinan-Boker3, Matan Joel Cohen4, Tair Ben-Porat2, Heba Gerasi5, Majd Amun5, Mahmud Abu-Gazala5, Abed Khalaileh5, Yoav Mintz5, Ram Elazary5. 1. General and Oncological Department C, Chaim Sheba Medical Center-Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, 5265601, Tel Hashomer, Israel. goldenshluger@gmail.com. 2. Department of Nutrition, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. 3. Israel Ministry of Health, Center for Disease Control, Ramat Gan, Israel. 4. Clalit Health Services, Jerusalem District, Israel. 5. Department of Surgery, Hadassah-Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel.
Abstract
OBJECTIVE: To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG). METHODS: The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery. RESULTS: We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (P = 0.018), higher baseline BMI (P = 0.003), and higher number of medications (P < 0.001) were negative predictors for EWL%. Total weekly hours of physical activity was found to be a positive predictor for EWL% (P = 0.008). Remission rates of co-morbidities were 83.5% for dyslipidemia (P < 0.001), 65.8% for hypertension (P < 0.001), 62.1% for type 2 diabetes mellitus (T2DM) (P < 0.001), and 60.7% for gastroesophageal reflux (GERD) (P < 0.001). Late gastrointestinal symptoms were as follows: emesis in 25.9%, constipation in 24.7%, diarrhea in 4.5%, food intolerance in 22.5% and alopecia in 42.7% of the patients. CONCLUSION: Our study shows LSG as a potential tool in achieving almost 75% of EWL% with significant remission of co-morbidities, along with various late gastrointestinal symptoms.
OBJECTIVE: To evaluate the outcomes, weight loss predictors, and gastrointestinal symptoms of patients after laparoscopic sleeve gastrectomy (LSG). METHODS: The postoperative medical status of the patients was obtained retrospectively using a questionnaire and was compared to existing medical data before the surgery. RESULTS: We included 201 candidates, 178 patients completed mean of 3 years of follow-up. Mean excess body weight loss (%EWL) was 65.14% ± 15.74 at 6 months, 78.53% ± 20.28 at 12 months, and 74.32% ± 23.92 at 3 years after LSG. Older age (P = 0.018), higher baseline BMI (P = 0.003), and higher number of medications (P < 0.001) were negative predictors for EWL%. Total weekly hours of physical activity was found to be a positive predictor for EWL% (P = 0.008). Remission rates of co-morbidities were 83.5% for dyslipidemia (P < 0.001), 65.8% for hypertension (P < 0.001), 62.1% for type 2 diabetes mellitus (T2DM) (P < 0.001), and 60.7% for gastroesophageal reflux (GERD) (P < 0.001). Late gastrointestinal symptoms were as follows: emesis in 25.9%, constipation in 24.7%, diarrhea in 4.5%, food intolerance in 22.5% and alopecia in 42.7% of the patients. CONCLUSION: Our study shows LSG as a potential tool in achieving almost 75% of EWL% with significant remission of co-morbidities, along with various late gastrointestinal symptoms.
Authors: Martina de Zwaan; Anja Hilbert; Lorraine Swan-Kremeier; Heather Simonich; Kathy Lancaster; L Michael Howell; Tim Monson; Ross D Crosby; James E Mitchell Journal: Surg Obes Relat Dis Date: 2009-09-03 Impact factor: 4.734
Authors: Kristina H Lewis; Ming Ji; Yun Bai; David E Arterburn; Bhumi B Bhakta; Melissa Cornejo; Cecelia L Crawford; Adam Drewnowski; Marlaine Figueroa Gray; Darren D Moore; Sameer B Murali; Silvia R Paz; Brianna Taylor; Tae K Yoon; Deborah Rohm Young; Karen J Coleman Journal: Appetite Date: 2021-02-04 Impact factor: 5.016
Authors: Abdel-Naser Elzouki; Muhammad-Aamir Waheed; Salah Suwileh; Islam Elzouki; Hisham Swehli; Maryam Alhitmi; Mona Saad; Elmukhtar Habas; Suhail A Doi; Mohammed I Danjuma Journal: Surg Open Sci Date: 2021-11-19