| Literature DB >> 2897007 |
J Launes1, P Nikkinen, L Lindroth, A L Brownell, K Liewendahl, M Iivanainen.
Abstract
Brain perfusion was studied in 14 patients with acute encephalitis by use of 123I-iodoamphetamine or 99mTc-hexamethylpropyleneamine oxime and single photon emission computed tomography (SPECT), the first examination being made 4-11 days after onset of encephalitis symptoms. All 6 patients with herpes simplex virus encephalitis (HSVE) had strongly increased accumulation of radiotracer in the affected temporal lobe; in the remaining 8 results were normal. At the time of the first SPECT conventional CT images were normal in all patients. The SPECT abnormality in HSVE gradually converted over 4-10 weeks from increased tracer accumulation to greatly subnormal accumulation. Brain perfusion SPECT may be helpful in the early diagnosis of HSVE.Entities:
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Year: 1988 PMID： 2897007 DOI： 10.1016/s0140-6736(88)92010-7
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321