Literature DB >> 28969294

Point of Care- A Novel Approach to Periodontal Diagnosis-A Review.

Nancy Srivastava1, Prathibha Anand Nayak2, Shivendra Rana3.   

Abstract

Periodontal disease, one of the prevalent oral diseases, is characterized by gingival inflammation and periodontal tissue destruction. Diagnosing this disease is challenging to the clinicians as the disease process is discontinuous and shows periods of exacerbation and remission. Traditional diagnostic methods basically tells about the past tissue destruction so new diagnostic methods are required which is able to detect the active state of the disease, determine the future progression and also estimates the response to the therapy, thereby helping in the better clinical management of the patient. Both saliva and Gingival crevicular fluid (GCF) are believed to be reliable medium to detect the biomarkers which plays a pivotal role in measuring the disease activity. Keeping these observations in mind rapid chairside tests are developed to diagnose periodontal disease called as Point of Care (POC) diagnostics which simplifies diagnosis and helps in improving the prognosis. This review article highlights about the biomarkers used in the diagnosis and throws light on the various available point of care diagnostic devices.

Entities:  

Keywords:  Biomarkers; Periodontal disease; Saliva

Year:  2017        PMID: 28969294      PMCID: PMC5620935          DOI: 10.7860/JCDR/2017/26626.10411

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  33 in total

Review 1.  Saliva testing--a nontraditional diagnostic tool.

Authors:  S M Miller
Journal:  Clin Lab Sci       Date:  1994 Jan-Feb

2.  Gingival crevice fluid--an introduction.

Authors:  Veli-Jukka Uitto
Journal:  Periodontol 2000       Date:  2003       Impact factor: 7.589

Review 3.  Potential for gingival crevice fluid measures as predictors of risk for periodontal diseases.

Authors:  Catherine M E Champagne; William Buchanan; Michael S Reddy; John S Preisser; James D Beck; Steven Offenbacher
Journal:  Periodontol 2000       Date:  2003       Impact factor: 7.589

Review 4.  Detection of high-risk groups and individuals for periodontal diseases: laboratory markers from analysis of gingival crevicular fluid.

Authors:  M A Curtis; I R Gillett; G S Griffiths; M F Maiden; J A Sterne; D T Wilson; J M Wilton; N W Johnson
Journal:  J Clin Periodontol       Date:  1989-01       Impact factor: 8.728

Review 5.  Point-of-care diagnostics enter the mouth.

Authors:  Lawrence A Tabak
Journal:  Ann N Y Acad Sci       Date:  2007-02-15       Impact factor: 5.691

6.  Trypsin-like activity in subgingival plaque. A diagnostic marker for spirochetes and periodontal disease?

Authors:  W J Loesche; S A Syed; J Stoll
Journal:  J Periodontol       Date:  1987-04       Impact factor: 6.993

7.  A new ultrasensitive chemiluminescent assay for the site-specific quantification of alkaline phosphatase in gingival crevicular fluid.

Authors:  I L Chapple; J B Matthews; G H Thorpe; H D Glenwright; J M Smith; M S Saxby
Journal:  J Periodontal Res       Date:  1993-07       Impact factor: 4.419

Review 8.  Saliva: an emerging biofluid for early detection of diseases.

Authors:  Yu-Hsiang Lee; David T Wong
Journal:  Am J Dent       Date:  2009-08       Impact factor: 1.522

9.  A longitudinal study of aspartate aminotransferase in human gingival crevicular fluid.

Authors:  D A Chambers; P B Imrey; R L Cohen; J M Crawford; M E Alves; T A McSwiggin
Journal:  J Periodontal Res       Date:  1991-03       Impact factor: 4.419

10.  Saliva: A diagnostic biomarker of periodontal diseases.

Authors:  Priti Basgauda Patil; Basgauda Ramesh Patil
Journal:  J Indian Soc Periodontol       Date:  2011-10
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  6 in total

1.  Update on the Role of Cytokines as Oral Biomarkers in the Diagnosis of Periodontitis.

Authors:  Triana Blanco-Pintos; Alba Regueira-Iglesias; Carlos Balsa-Castro; Inmaculada Tomás
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

2.  Periodontal disease and targeted prevention using aMMP-8 point-of-care oral fluid analytics in the COVID-19 era.

Authors:  Ismo T Räisänen; Kehinde A Umeizudike; Pirjo Pärnänen; Pia Heikkilä; Taina Tervahartiala; Solomon O Nwhator; Andreas Grigoriadis; Dimitra Sakellari; Timo Sorsa
Journal:  Med Hypotheses       Date:  2020-09-16       Impact factor: 1.538

3.  Automated Pre-Analytic Processing of Whole Saliva Using Magnet-Beating for Point-of-Care Protein Biomarker Analysis.

Authors:  Benita Johannsen; Lara Müller; Desirée Baumgartner; Lena Karkossa; Susanna M Früh; Nagihan Bostanci; Michal Karpíšek; Roland Zengerle; Nils Paust; Konstantinos Mitsakakis
Journal:  Micromachines (Basel)       Date:  2019-11-30       Impact factor: 2.891

4.  Oral Diagnostic Methods for the Detection of Periodontal Disease.

Authors:  Liza L Ramenzoni; Marc P Lehner; Manuela E Kaufmann; Daniel Wiedemeier; Thomas Attin; Patrick R Schmidlin
Journal:  Diagnostics (Basel)       Date:  2021-03-22

Review 5.  The Role of Epigenetic and Biological Biomarkers in the Diagnosis of Periodontal Disease: A Systematic Review Approach.

Authors:  Erin Faulkner; Adelaide Mensah; Aoife M Rodgers; Lyndsey R McMullan; Aaron J Courtenay
Journal:  Diagnostics (Basel)       Date:  2022-04-07

6.  Lactate Dehydrogenase and β-Glucuronidase as Salivary Biochemical Markers of Periodontitis Among Smokers and Non-Smokers.

Authors:  Syed A Ali; Ravi L Telgi; Amit Tirth; Irfan Q Tantry; Abdul Aleem
Journal:  Sultan Qaboos Univ Med J       Date:  2018-12-19
  6 in total

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