OBJECTIVE: The purpose of this study was to assess the impact of the presence of peripheral arterial disease (PAD) on left ventricular (LV) function in patients with coronary artery disease (CAD) presenting with acute coronary syndrome (ACS). SUBJECTS AND METHODS: The medical records of the patients who were referred to Ankara Bayindir Hospital, Ankara, Turkey, due to a first episode of ACS were reviewed. Patients with concomitant PAD and CAD (group 1) were compared with those who had CAD only (group 2). The Mann-Whitney U and χ2 tests were used to compare continuous and categorical variables, respectively. RESULTS: Baseline demographic data of 53 patients with PAD + CAD (42 men and 11 women; mean age 62.5 ± 9.5 years) and a group of 60 patients with CAD only (41 men and 19 women; mean age 59.9 ± 9.8 years) were similar, except for the serum creatinine level which was higher in group 1 than in group 2 (1.32 ± 0.34 vs. 1.03 ± 0.22 mg/dL, p < 0.001). Patients with CAD + PAD had significantly higher Gensini scores (62.6 ± 19.7 vs. 41.4 ± 26.8, p = 0.004) and more 3-vessel disease than patients with CAD alone (62.2 vs. 31.6%, p < 0.045). There was a significant difference between the 2 groups regarding the LV ejection fraction at the time of the diagnosis (52.0 ± 8.2% in the CAD + PAD group and 43.7 ± 13.3% in the CAD-alone group; p = 0.017). CONCLUSION: CAD concomitant with PAD was associated with preserved LV function at early stages of diagnosis in patients with ACS.
OBJECTIVE: The purpose of this study was to assess the impact of the presence of peripheral arterial disease (PAD) on left ventricular (LV) function in patients with coronary artery disease (CAD) presenting with acute coronary syndrome (ACS). SUBJECTS AND METHODS: The medical records of the patients who were referred to Ankara Bayindir Hospital, Ankara, Turkey, due to a first episode of ACS were reviewed. Patients with concomitant PAD and CAD (group 1) were compared with those who had CAD only (group 2). The Mann-Whitney U and χ2 tests were used to compare continuous and categorical variables, respectively. RESULTS: Baseline demographic data of 53 patients with PAD + CAD (42 men and 11 women; mean age 62.5 ± 9.5 years) and a group of 60 patients with CAD only (41 men and 19 women; mean age 59.9 ± 9.8 years) were similar, except for the serum creatinine level which was higher in group 1 than in group 2 (1.32 ± 0.34 vs. 1.03 ± 0.22 mg/dL, p < 0.001). Patients with CAD + PAD had significantly higher Gensini scores (62.6 ± 19.7 vs. 41.4 ± 26.8, p = 0.004) and more 3-vessel disease than patients with CAD alone (62.2 vs. 31.6%, p < 0.045). There was a significant difference between the 2 groups regarding the LV ejection fraction at the time of the diagnosis (52.0 ± 8.2% in the CAD + PAD group and 43.7 ± 13.3% in the CAD-alone group; p = 0.017). CONCLUSION: CAD concomitant with PAD was associated with preserved LV function at early stages of diagnosis in patients with ACS.
Authors: Mark J Makowsky; Finlay A McAlister; P Diane Galbraith; Danielle A Southern; William A Ghali; Merril L Knudtson; Ross T Tsuyuki Journal: Am Heart J Date: 2007-10-25 Impact factor: 4.749
Authors: Danny Chu; Faisal G Bakaeen; Xing Li Wang; Tam K Dao; Scott A LeMaire; Joseph S Coselli; Joseph Huh Journal: Ann Thorac Surg Date: 2008-10 Impact factor: 4.330
Authors: Hans Erik Bøtker; Rajesh Kharbanda; Michael R Schmidt; Morten Bøttcher; Anne K Kaltoft; Christian J Terkelsen; Kim Munk; Niels H Andersen; Troels M Hansen; Sven Trautner; Jens Flensted Lassen; Evald Høj Christiansen; Lars R Krusell; Steen D Kristensen; Leif Thuesen; Søren S Nielsen; Michael Rehling; Henrik Toft Sørensen; Andrew N Redington; Torsten T Nielsen Journal: Lancet Date: 2010-02-27 Impact factor: 79.321
Authors: Stavros P Loukogeorgakis; Rupert Williams; Anna T Panagiotidou; Shyamsunder K Kolvekar; Ann Donald; Tim J Cole; Derek M Yellon; John E Deanfield; Raymond J MacAllister Journal: Circulation Date: 2007-08-27 Impact factor: 29.690
Authors: Zafer Elbasan; Durmuş Yıldıray Şahin; Mustafa Gür; Gökhan Gözübüyük; Rabia Eker Akıllı; Nermin Yıldız Koyunsever; Caner Türkoğlu; Ali Kıvrak; Arafat Yıldırım; Murat Caylı Journal: Med Princ Pract Date: 2013-01-15 Impact factor: 1.927