Literature DB >> 28961015

Diaporisoindoles A-C: Three Isoprenylisoindole Alkaloid Derivatives from the Mangrove Endophytic Fungus Diaporthe sp. SYSU-HQ3.

Hui Cui1, Yun Lin1, Mingchu Luo1, Yongjun Lu1, Xishan Huang1, Zhigang She1.   

Abstract

Diaporisoindoles A (1) and B (2), two novel isoprenylisoindole alkaloids, and an unusual diisoprenylisoindole dimer diaporisoindole C (3), together with a precursor tenellone C (4) were all isolated from the endophytic fungus Diaporthe sp. SYSU-HQ3. The absolute configurations of 1-4 were elucidated by spectroscopic analysis, X-ray diffraction, and quantum chemical calculations. Diaporisoindole A (1) and tenellone C (4) exhibited inhibitory activity against Mycobacterium tuberculosis protein tyrosine phosphatase B with IC50 values of 4.2 and 5.2 μM.

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Year:  2017        PMID： 28961015     DOI： 10.1021/acs.orglett.7b02748

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

1.  Inhibitory Effects and Mechanism of the Natural Compound Diaporthein B Extracted from Marine-Derived Fungi on Colon Cancer Cells.

Authors:  Peihua Tang; Dandan Liu; Zheli Wu; Hui Cui; Ren Zhang; Zaoyuan Kuang
Journal:  Molecules       Date:  2022-05-05       Impact factor: 4.927

2.  Two Antimicrobial Heterodimeric Tetrahydroxanthones with a 7,7'-Linkage from Mangrove Endophytic Fungus Aspergillus flavus QQYZ.

Authors:  Zhenming Zang; Wencong Yang; Hui Cui; Runlin Cai; Chunyuan Li; Ge Zou; Bo Wang; Zhigang She
Journal:  Molecules       Date:  2022-04-22       Impact factor: 4.927

3.  New Benzofuranoids and Phenylpropanoids from the Mangrove Endophytic Fungus, Aspergillus sp. ZJ-68.

Authors:  Runlin Cai; Hongming Jiang; Zhenming Zang; Chunyuan Li; Zhigang She
Journal:  Mar Drugs       Date:  2019-08-18       Impact factor: 5.118

4.  Metabolites With Cytotoxic Activities From the Mangrove Endophytic Fungus Fusarium sp. 2ST2.

Authors:  Yan Chen; Guisheng Wang; Yilin Yuan; Ge Zou; Wencong Yang; Qi Tan; Wenyi Kang; Zhigang She
Journal:  Front Chem       Date:  2022-02-15       Impact factor: 5.221

Review 5.  Endophytic Fungi: An Effective Alternative Source of Plant-Derived Bioactive Compounds for Pharmacological Studies.

Authors:  Juan Wen; Samuel Kumi Okyere; Shu Wang; Jianchen Wang; Lei Xie; Yinan Ran; Yanchun Hu
Journal:  J Fungi (Basel)       Date:  2022-02-20

6.  Application of Principal Component Analysis (PCA) to the Evaluation and Screening of Multiactivity Fungi.

Authors:  Zonglin Yang; Yaqi Shi; Pinglin Li; Kanghong Pan; Guoqiang Li; Xianguo Li; Shuo Yao; Dahai Zhang
Journal:  J Ocean Univ China       Date:  2022-05-13       Impact factor: 0.913

Review 7.  Unusual Secondary Metabolites from the Mangrove Ecosystems: Structures, Bioactivities, Chemical, and Bio-Syntheses.

Authors:  Meng-Jun Wu; Baofu Xu; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2022-08-20       Impact factor: 6.085

8.  Bioactive Monoterpenes and Polyketides from the Ascidian-Derived Fungus Diaporthe sp. SYSU-MS4722.

Authors:  Guifa Zhai; Senhua Chen; Hongjie Shen; Heng Guo; Minghua Jiang; Lan Liu
Journal:  Mar Drugs       Date:  2022-08-29       Impact factor: 6.085

Review 9.  Lead Compounds from Mangrove-Associated Microorganisms.

Authors:  Elena Ancheeva; Georgios Daletos; Peter Proksch
Journal:  Mar Drugs       Date:  2018-09-07       Impact factor: 5.118

10.  Polyketide Derivatives, Guhypoxylonols A-D from a Mangrove Endophytic Fungus Aspergillus sp. GXNU-Y45 That Inhibit Nitric Oxide Production.

Authors:  Xiaoya Qin; Jiguo Huang; Dexiong Zhou; Wenxiu Zhang; Yanjun Zhang; Jun Li; Ruiyun Yang; Xishan Huang
Journal:  Mar Drugs       Date:  2021-12-21       Impact factor: 5.118
  10 in total

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