BACKGROUND: Selective upper airway stimulation (UAS) has shown effectiveness in treating patients with obstructive sleep apnea (OSA). The terminating branches of the hypoglossal nerve show a wide complexity, requiring careful discernment of a functional breakpoint between branches for inclusion and exclusion from the stimulation cuff electrode. The purpose of this study was to describe and categorize the topographic phenotypes of these branches. METHODS: Thirty patients who received an implant with selective UAS from July 2015 to June 2016 were included. All implantations were recorded using a microscope and resultant tongue motions were captured perioperatively for comparison. RESULTS: Eight different variations of the branches were encountered and described, both in a tabular numeric fashion and in pictorial schema. CONCLUSION: The examinations showed the complex phenotypic surgical anatomy of the hypoglossal nerve. A schematic classification system has been developed to help surgeons identify the optimal location for cuff placement in UAS.
BACKGROUND: Selective upper airway stimulation (UAS) has shown effectiveness in treating patients with obstructive sleep apnea (OSA). The terminating branches of the hypoglossal nerve show a wide complexity, requiring careful discernment of a functional breakpoint between branches for inclusion and exclusion from the stimulation cuff electrode. The purpose of this study was to describe and categorize the topographic phenotypes of these branches. METHODS: Thirty patients who received an implant with selective UAS from July 2015 to June 2016 were included. All implantations were recorded using a microscope and resultant tongue motions were captured perioperatively for comparison. RESULTS: Eight different variations of the branches were encountered and described, both in a tabular numeric fashion and in pictorial schema. CONCLUSION: The examinations showed the complex phenotypic surgical anatomy of the hypoglossal nerve. A schematic classification system has been developed to help surgeons identify the optimal location for cuff placement in UAS.
Authors: Markus Wirth; Daniel Unterhuber; Franziska von Meyer; Benedikt Hofauer; Armin Ott; Guenther Edenharter; Danny J Eckert; Clemens Heiser Journal: J Clin Sleep Med Date: 2020-01-13 Impact factor: 4.062
Authors: Clemens Heiser; J Ulrich Sommer; Benedikt Hofauer; Nico de Vries; Madeline Jl Ravesloot; Olivier M Vanderveken; Daniel Jira Journal: OTO Open Date: 2022-07-06
Authors: Clemens Heiser; Armin Steffen; Maurits Boon; Benedikt Hofauer; Karl Doghramji; Joachim T Maurer; J Ulrich Sommer; Ryan Soose; Patrick J Strollo; Richard Schwab; Erica Thaler; Kirk Withrow; Alan Kominsky; Christopher Larsen; Eric J Kezirian; Jennifer Hsia; Stanley Chia; John Harwick; Kingman Strohl; Reena Mehra Journal: Eur Respir J Date: 2019-01-03 Impact factor: 16.671
Authors: Maria V Suurna; Ofer Jacobowitz; Jolie Chang; Ioannis Koutsourelakis; David Smith; Uri Alkan; Mark D'Agostino; Maurits Boon; Clemens Heiser; Paul Hoff; Colin Huntley; David Kent; Alan Kominsky; Richard Lewis; Joachim T Maurer; Madeline J Ravesloot; Ryan Soose; Armin Steffen; Edward M Weaver; Amy M Williams; Tucker Woodson; Kathleen Yaremchuk; Stacey L Ishman Journal: J Clin Sleep Med Date: 2021-12-01 Impact factor: 4.062