Literature DB >> 28947219

Comparison between Saline Solution Containing Heparin versus Saline Solution in the Lock of Totally Implantable Catheters.

Antonio Rafael de Oliveira Brito1, Kenji Nishinari2, Paulo Fernandes Saad3, Karen Ruggeri Saad3, Monica Aparecida Tomé Pereira3, Suellen Cristina Dias Emídio4, Guilherme Yazbek2, Guilherme Andre Zottele Bomfim2, Rafael Noronha Cavalcante2, Mariana Krutman2, Marcelo Passos Teivelis2, Bruno Soriano Pignataro2, Igor Yoshio Imagawa Fonseca2, Guilherme Centofanti2, Bruno Leonardo Freitas Soares5.   

Abstract

BACKGROUND: There are only 3 studies comparing the efficacy of 2 different types of lock used in totally implantable catheters regarding occlusion or reflux dysfunction. The present study contains the largest published casuistry (862 patients) and is the only one that analyzes 3 parameters: occlusion, reflux dysfunction, and flow dysfunction.
METHODS: This was a retrospective study of patients operated at a large oncology center and followed up in the outpatient clinic between 2007 and 2015. The patients were divided into 2 groups according to the type of lock: the Hep group (heparine), whose lock was composed of saline solution 0.9% with heparin (100 IU/mL) and the SS group (saline solution), whose lock was composed of saline solution 0.9%.
RESULTS: The Hep group was composed of 270 patients (31%) and the SS group of 592 patients (69%). Regarding occlusion, there were 8 cases in the Hep group (2.96%) and 8 in the SS group (1.35%; P = 0.11); in relation to reflux dysfunction, there were 8 cases in the Hep group (2.96%) and 8 in the SS group (1.35%; P = 0.11); in relation to flow dysfunction, there was 1 case in the Hep group (0.37%) and 4 cases in the SS group (0.68%; P = 1).
CONCLUSIONS: There was no statistically significant difference between the groups regarding occlusion, reflux dysfunction, and flow dysfunction.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28947219     DOI: 10.1016/j.avsg.2017.09.015

Source DB:  PubMed          Journal:  Ann Vasc Surg        ISSN: 0890-5096            Impact factor:   1.466


  5 in total

1.  Normal saline (0.9% sodium chloride) versus heparin intermittent flushing for the prevention of occlusion in long-term central venous catheters in infants and children.

Authors:  Natalie K Bradford; Rachel M Edwards; Raymond J Chan
Journal:  Cochrane Database Syst Rev       Date:  2020-04-30

2. 

Authors:  Terri Jabaley; Niya Xiong; Susanne Conley; Teresa Mazeika; Danielle Johnson; Brenda A Biggins; Nancy Hilton; Fangxin Hong
Journal:  Can Oncol Nurs J       Date:  2022-04-01

3.  Transitioning from heparin to saline locks for central venous access devices in oncology: An evidence-based practice approach.

Authors:  Terri Jabaley; Niya Xiong; Susanne Conley; Teresa Mazeika; Danielle Johnson; Brenda A Biggins; Nancy Hilton; Fangxin Hong
Journal:  Can Oncol Nurs J       Date:  2022-04-01

Review 4.  Dosage of heparin for patency of the totally implanted central venous catheter in cancer patients.

Authors:  Francisca Jane Gomes de Oliveira; Andrea Bezerra Rodrigues; Islane Costa Ramos; Joselany Áfio Caetano
Journal:  Rev Lat Am Enfermagem       Date:  2020-06-19

Review 5.  Heparin flush vs. normal saline flush to maintain the patency of central venous catheter among adult patients: A systematic review and meta-analysis.

Authors:  Suresh K Sharma; Shiv K Mudgal; Rakhi Gaur; Rakesh Sharma; Maneesh Sharma; Kalpana Thakur
Journal:  J Family Med Prim Care       Date:  2019-09-30
  5 in total

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