| Literature DB >> 28945707 |
Chuan-Le Xiao1,2,3,4, Ying Chen2, Shang-Qian Xie1,5, Kai-Ning Chen1, Yan Wang1, Yue Han1,6, Feng Luo7, Zhi Xie1.
Abstract
We present a tool that combines fast mapping, error correction, and de novo assembly (MECAT; accessible at https://github.com/xiaochuanle/MECAT) for processing single-molecule sequencing (SMS) reads. MECAT's computing efficiency is superior to that of current tools, while the results MECAT produces are comparable or improved. MECAT enables reference mapping or de novo assembly of large genomes using SMS reads on a single computer.Mesh:
Year: 2017 PMID: 28945707 DOI: 10.1038/nmeth.4432
Source DB: PubMed Journal: Nat Methods ISSN: 1548-7091 Impact factor: 28.547