Literature DB >> 28944317

Comparison of Regional vs. General Anesthesia for Surgical Repair of Open-Globe Injuries at a University Referral Center.

Andrew J McClellan1, Jacquelyn J Daubert1, Nidhi Relhan1, Kimberly D Tran1, Harry W Flynn1, Steven Gayer2.   

Abstract

PURPOSE: This study compares the clinical features and physician selection of either Regional Anesthesia (peribulbar or retrobulbar block) with Monitored Anesthesia Care (RA-MAC) or General Anesthesia (GA) for open globe injury repair.
DESIGN: A non-randomized, comparative, retrospective case series at a University Referral Center. PARTICIPANTS: All adult repairable open globe injuries receiving primary repair between January 1st, 2004 and December 31st, 2014 (11 years). Exclusion criteria were patients less than 18 years of age and those treated with primary enucleation.
METHODS: Data was gathered via retrospective chart review. MAIN OUTCOME MEASURES: Data collected from each patient was age, gender, injury type, location, length of wound, presenting visual acuity, classification of anesthesia used, duration of the procedure performed, months of clinical follow-up, and final visual acuity.
RESULTS: During the 11 years study period, 448 patients were identified who had open globe injuries with documented information on zone of injury. Globe injury repair was performed using RA-MAC in 351/448 (78%) patients and general anesthesia in 97/448 (22%) patients. Zone 1, 2 and 3 injuries were recorded in 241, 135, and 72 patients respectively. The rates in specific zones, of RA-MAC versus GA were as follows: Zone 1 - 213/241 (88%) vs 28/241 (12%), Zone 2 - 104/135 (77%) vs 31/135 (23%) and Zone 3 - 34/72 (47%) vs 38/72 (53%). Open globe injuries repaired under RA-MAC had significantly shorter wound length (p<0.001), more anterior wound location (p<0.001) and shorter operative times (p<0.001). RA-MAC cases also had a better presenting and final visual acuity (p<0.001). Neither class of anesthesia conferred a greater visual acuity improvement (p=0.06). The use of GA did not cause any delay in the time elapsed from injury until surgical repair (p=0.74).
CONCLUSIONS: RA-MAC is a reasonable alternative to GA for the repair of open globe injuries in selected adult patients. RA-MAC was selected more often for Zone 1 and Zone 2 injuries. For eyes with Zone 3 injuries, there are equal selection ratio for RA-MAC and GA.

Entities:  

Year:  2017        PMID: 28944317      PMCID: PMC5607023          DOI: 10.1016/j.oret.2016.11.006

Source DB:  PubMed          Journal:  Ophthalmol Retina        ISSN: 2468-6530


  11 in total

1.  Effect of combined peribulbar and retrobulbar injection of large volumes of anesthetic agents on the intraocular pressure.

Authors:  D Meyer; R C Hamilton; R G Loken; H V Gimbel
Journal:  Can J Ophthalmol       Date:  1992-08       Impact factor: 1.882

2.  The effect of succinylcholine on the extraocular muscles.

Authors:  H A LINCOFF; G M BREININ; A G DE VOE
Journal:  Am J Ophthalmol       Date:  1957-03       Impact factor: 5.258

Review 3.  Management of intraocular foreign bodies: a clinical flight plan.

Authors:  D Wilkin Parke; Harry W Flynn; Yale L Fisher
Journal:  Can J Ophthalmol       Date:  2013-02       Impact factor: 1.882

4.  Regional anesthesia with monitored anesthesia care for surgical repair of selected open globe injuries.

Authors:  Ingrid U Scott; Steven Gayer; Irene Voo; Harry W Flynn; Jose R Diniz; Anna Venkatraman
Journal:  Ophthalmic Surg Lasers Imaging       Date:  2005 Mar-Apr

5.  Brain-stem anesthesia after retrobulbar block.

Authors:  E F Meyers
Journal:  Arch Ophthalmol       Date:  1985-09

6.  Local anesthesia with intravenous sedation for surgical repair of selected open globe injuries.

Authors:  Ingrid U Scott; Cathleen M Mccabe; Harry W Flynn; Dagmar R Lemus; Joyce C Schiffman; Dale S Reynolds; Mauricio B Pereira; Armando Belfort; Steven Gayer
Journal:  Am J Ophthalmol       Date:  2002-11       Impact factor: 5.258

7.  A system for classifying mechanical injuries of the eye (globe). The Ocular Trauma Classification Group.

Authors:  D J Pieramici; P Sternberg; T M Aaberg; W Z Bridges; A Capone; J A Cardillo; E de Juan; F Kuhn; T A Meredith; W F Mieler; T W Olsen; P Rubsamen; T Stout
Journal:  Am J Ophthalmol       Date:  1997-06       Impact factor: 5.258

8.  Intraocular pressure changes in a Nigerian population--effects of tracheal tube and laryngeal mask airway insertion and removal.

Authors:  J O Igboko; I Desalu; F B Akinsola; O T Kushimo
Journal:  Niger Postgrad Med J       Date:  2009-06

9.  Succinylcholine increases intraocular pressure in the human eye with the extraocular muscles detached.

Authors:  R E Kelly; M Dinner; L S Turner; B Haik; D H Abramson; P Daines
Journal:  Anesthesiology       Date:  1993-11       Impact factor: 7.892

10.  Regional anaesthesia for surgical repair in selected open globe injuries in adults.

Authors:  Arunangshu Chakraborty; Samir K Bandyopadhyay; Somnath Mukhopadhyay
Journal:  Saudi J Ophthalmol       Date:  2012-01-30
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  1 in total

Review 1.  Open Globe Injuries: Review of Evaluation, Management, and Surgical Pearls.

Authors:  Yujia Zhou; Mark DiSclafani; Lauren Jeang; Ankit A Shah
Journal:  Clin Ophthalmol       Date:  2022-08-10
  1 in total

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