Literature DB >> 2894336

Somatostatin does not reduce oesophageal variceal pressure in liver cirrhotics.

G Kleber1, T Sauerbruch, G Fischer, G Paumgartner.   

Abstract

Transmural oesophageal variceal pressure was determined by direct puncture of the varices in 27 patients with liver cirrhosis and oesophageal varices. Variceal pressure was not influenced three to six minutes after somatostatin bolus administration and slightly increased during somatostatin infusion. Thus, potential haemostatic benefits of somatostatin cannot be explained by pressure reductions in the varices.

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Year:  1988        PMID： 2894336      PMCID： PMC1433282          DOI： 10.1136/gut.29.2.153

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  10 in total

1.  Transection of the oesophagus for bleeding oesophageal varices.

Authors:  R N Pugh; I M Murray-Lyon; J L Dawson; M C Pietroni; R Williams
Journal:  Br J Surg       Date:  1973-08       Impact factor: 6.939

2.  Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects.

Authors:  G E Sonnenberg; U Keller; A Perruchoud; D Burckhardt; K Gyr
Journal:  Gastroenterology       Date:  1981-03       Impact factor: 22.682

3.  Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: comparison with vasopressin.

Authors:  J Bosch; D Kravetz; J Rodes
Journal:  Gastroenterology       Date:  1981-03       Impact factor: 22.682

4.  A prospective randomised controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage.

Authors:  S A Jenkins; J N Baxter; W Corbett; P Devitt; J Ware; R Shields
Journal:  Br Med J (Clin Res Ed)       Date:  1985-01-26

5.  Somatostatin not helpful in bleeding esophageal varices.

Authors:  S Raptis; C Zoupas
Journal:  N Engl J Med       Date:  1979-03-29       Impact factor: 91.245

6.  Effects of a somatostatin analogue SMS 201-995 on hepatic haemodynamics in the pig and on intravariceal pressure in man.

Authors:  S A Jenkins; J N Baxter; W A Corbett; R Shields
Journal:  Br J Surg       Date:  1985-12       Impact factor: 6.939

7.  Treatment of bleeding oesophageal varices with somatostatin.

Authors:  L Thulin; G Tydén; H Samnegård; O Muhrbeck; S Efendić
Journal:  Acta Chir Scand       Date:  1979

8.  Prognostic significance of serum bile acids in cirrhosis.

Authors:  G A Mannes; C Thieme; F Stellaard; T Wang; T Sauerbruch; G Paumgartner
Journal:  Hepatology       Date:  1986 Jan-Feb       Impact factor: 17.425

9.  Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basal conditions, Valsalva's manoeuvre and after glyceryltrinitrate application.

Authors:  M Staritz; T Poralla; K H Meyer zum Büschenfelde
Journal:  Gut       Date:  1985-05       Impact factor: 23.059

10.  Effect of somatostatin on oesophageal variceal pressure assessed by direct measurement.

Authors:  D Clements; J M Rhodes; E Elias
Journal:  J Hepatol       Date:  1986       Impact factor: 25.083
  10 in total
  10 in total

Review 1.  Therapeutic potential of a long acting somatostatin analogue in gastrointestinal diseases.

Authors:  L J O'Donnell; M J Farthing
Journal:  Gut       Date:  1989-09       Impact factor: 23.059

2.  Pressure of intraoesophageal varices assessed by fine needle puncture: its relation to endoscopic signs and severity of liver disease in patients with cirrhosis.

Authors:  G Kleber; T Sauerbruch; G Fischer; G Paumgartner
Journal:  Gut       Date:  1989-02       Impact factor: 23.059

3.  Octreotide in variceal bleeding.

Authors:  A K Burroughs
Journal:  Gut       Date:  1994       Impact factor: 23.059

Review 4.  Somatostatin analogues for acute bleeding oesophageal varices.

Authors:  Peter C Gøtzsche; Asbjørn Hróbjartsson
Journal:  Cochrane Database Syst Rev       Date:  2008-07-16

Review 5.  When endoscopic therapy or pharmacotherapy fails to control variceal bleeding: what should be done? Immediate control of bleeding by TIPS?

Authors:  Martin Rössle
Journal:  Langenbecks Arch Surg       Date:  2003-05-01       Impact factor: 3.445

Review 6.  Somatostatin in acute bleeding oesophageal varices. Pharmacology and rationale for use.

Authors:  E Hanisch; J Doertenbach; K H Usadel
Journal:  Drugs       Date:  1992       Impact factor: 9.546

7.  Assessment of variceal pressure by continuous non-invasive endoscopic registration: a placebo controlled evaluation of the effect of terlipressin and octreotide.

Authors:  F Nevens; W Van Steenbergen; S H Yap; J Fevery
Journal:  Gut       Date:  1996-01       Impact factor: 23.059

8.  Somatostatin v placebo in bleeding oesophageal varices: randomised trial and meta-analysis.

Authors:  P C Gøtzsche; I Gjørup; H Bonnén; N E Brahe; U Becker; F Burcharth
Journal:  BMJ       Date:  1995-06-10

9.  The effects of sandostatin (Octreotide, SMS 201-995) infusion on splanchnic and hepatic blood flow in an experimental model of hepatic metastases.

Authors:  D M Hemingway; S A Jenkins; T G Cooke
Journal:  Br J Cancer       Date:  1992-03       Impact factor: 7.640

10.  A prospective randomized controlled clinical trial comparing the effects of somatostatin and vasopressin for control of acute variceal bleeding in the patients with liver cirrhosis.

Authors:  Heon Young Lee; Heon Ju Lee; Seung Min Lee; Jun Hwan Kim; Soon Wook Kweon; Byung Seok Lee; Nam Jae Kim
Journal:  Korean J Intern Med       Date:  2003-09       Impact factor: 2.884
  10 in total

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