Literature DB >> 2857103

A prospective randomised controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage.

S A Jenkins, J N Baxter, W Corbett, P Devitt, J Ware, R Shields.   

Abstract

Twenty two patients were entered into a randomised controlled clinical trial comparing the efficacy of somatostatin and vasopressin in controlling acute variceal haemorrhage. Somatostatin was significantly more successful in controlling acute variceal haemorrhage than vasopressin (p = 0.003). Furthermore, no complications were observed during treatment with somatostatin.

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Year:  1985        PMID: 2857103      PMCID: PMC1417581          DOI: 10.1136/bmj.290.6464.275

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN: 0267-0623


  18 in total

1.  Multiple infusions of posterior pituitary extract in the treatment of bleeding esophageal varices.

Authors:  H O CONN; D J DALESSIO
Journal:  Ann Intern Med       Date:  1962-11       Impact factor: 25.391

2.  The use of surgical pituitrin in the control of esophageal varix bleeding; an experimental study and report of two cases.

Authors:  J H KEHNE; F A HUGHES; M L GOMPERTZ
Journal:  Surgery       Date:  1956-06       Impact factor: 3.982

3.  Inhibition of gastrin and gastric-acid secretion by growth-hormone release-inhibiting hormone.

Authors:  S R Bloom; C H Mortimer; M O Thorner; G M Besser; R Hall; A Gomez-Pan; V M Roy; R C Russell; D H Coy; A J Kastin; A V Schally
Journal:  Lancet       Date:  1974-11-09       Impact factor: 79.321

4.  Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: comparison with vasopressin.

Authors:  J Bosch; D Kravetz; J Rodes
Journal:  Gastroenterology       Date:  1981-03       Impact factor: 22.682

5.  Somatostatin and the gut.

Authors:  S R Bloom
Journal:  Gastroenterology       Date:  1978-07       Impact factor: 22.682

6.  Effect of growth hormone release-inhibiting hormone on gastric secretion, mucosal blood flow, and serum gastrin.

Authors:  S J Konturek; J Tasler; M Cieszkowski; D H Coy; A V Schally
Journal:  Gastroenterology       Date:  1976-05       Impact factor: 22.682

7.  Comparison of intravenous somatostatin and vasopressin infusions in treatment of acute variceal hemorrhage.

Authors:  D Kravetz; J Bosch; J Terés; J Bruix; A Rimola; J Rodés
Journal:  Hepatology       Date:  1984 May-Jun       Impact factor: 17.425

8.  [Results of conservatively treated upper arm fractures in adults (author's transl)].

Authors:  M Dallek; U Mommsen; H Schöntag; K H Jungbluth
Journal:  Langenbecks Arch Chir       Date:  1982

9.  Influence of somatostatin on carbohydrate disposal and absorption in diabetes mellitus.

Authors:  J Wahren
Journal:  Lancet       Date:  1976-12-04       Impact factor: 79.321

10.  [Effects of somatostatin in oesophagal bleeding (author's transl)].

Authors:  J Bringer; A Dubois; J L Richard; V T Chuong; T C Pham; G Vallat; J Mirouze
Journal:  Nouv Presse Med       Date:  1980-03-12
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  31 in total

1.  UK guidelines on the management of variceal haemorrhage in cirrhotic patients. British Society of Gastroenterology.

Authors:  R Jalan; P C Hayes
Journal:  Gut       Date:  2000-06       Impact factor: 23.059

Review 2.  Gastroenterology.

Authors:  L J O'Donnell; E M Alstead; M J Farthing
Journal:  Postgrad Med J       Date:  1990-06       Impact factor: 2.401

Review 3.  The management of an episode of variceal bleeding.

Authors:  A E Gimson; D Westaby
Journal:  Postgrad Med J       Date:  1991-02       Impact factor: 2.401

Review 4.  Therapeutic potential of a long acting somatostatin analogue in gastrointestinal diseases.

Authors:  L J O'Donnell; M J Farthing
Journal:  Gut       Date:  1989-09       Impact factor: 23.059

Review 5.  Portal hypertension--25 years of progress.

Authors:  B R MacDougall; D Westaby; L A Blendis
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

6.  Bleeding varices in the elderly.

Authors:  D R Triger
Journal:  Gut       Date:  1992-08       Impact factor: 23.059

7.  Somatostatin reduces gastric mucosal blood flow in patients with portal hypertensive gastropathy: a randomized, double-blind crossover study.

Authors:  M K Li; J J Sung; K S Woo; J Sanderson; N W Leung; L M Yu; C P Tsui; S C Chung; F W Leung
Journal:  Dig Dis Sci       Date:  1996-12       Impact factor: 3.199

Review 8.  Somatostatin in portal hypertension.

Authors:  J S Morgan; R J Groszmann
Journal:  Dig Dis Sci       Date:  1989-03       Impact factor: 3.199

Review 9.  The use of sclerotherapy for the management of oesophageal varices in portal hypertension.

Authors:  J Terblanche
Journal:  Surg Endosc       Date:  1988       Impact factor: 4.584

10.  Octreotide in variceal bleeding.

Authors:  A K Burroughs
Journal:  Gut       Date:  1994       Impact factor: 23.059

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