Hirohito Kanamoto1, Yawara Eguchi2, Yasuhiro Oikawa3, Sumihisa Orita1, Kazuhide Inage1, Kazuki Fujimoto1, Yasuhiro Shiga1, Koki Abe1, Masahiro Inoue1, Hideyuki Kinoshita1, Koji Matsumoto4, Yoshitada Masuda4, Takeo Furuya1, Masao Koda1, Yasuchika Aoki5, Atsuya Watanabe5, Kazuhisa Takahashi1, Seiji Ohtori1. 1. 1 Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Inohana, Chuo-ku , Graduate School of Medicine, Chiba University, Inohana, Chuo-ku , Chiba , Japan. 2. 2 Department of Orthopaedic Surgery, Shimoshizu National HospitalShikawatashi, Yotsukaido , Shimoshizu National HospitalShikawatashi, Yotsukaido , Shimoshizu National HospitalShikawatashi, Yotsukaido , Chiba , Japan. 3. 3 Division of Orthopaedic Surgery, Chiba Children's Hospital, Heta-Chou, Midori-ku , Chiba Children's Hospital, Heta-Chou, Midori-ku , Chiba , Japan. 4. 4 Department of Radiology, Chiba University Hospital, Inohana, Chuo-ku , Chiba University Hospital, Inohana, Chuo-ku , Chiba , Japan. 5. 5 Department of Orthopaedic Surgery, Eastern Chiba Medical CenterOkayamadai, Togane , Eastern Chiba Medical CenterOkayamadai, Togane , Eastern Chiba Medical CenterOkayamadai, Togane , Chiba , Japan.
Abstract
OBJECTIVE: We investigated high resolution diffusion tensor imaging (DTI) of lumbar nerves with reduced field of view (rFOV) using 3 T MRI. METHODS: DTI measured with rFOV was compared with conventional FOV (cFOV) 3.0 T MRI in 5 healthy volunteers and 10 patients with degenerative lumbar disorders. The intracanal, foramina and extraforamina of the L5 nerve were established as the regions of interest and fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values were measured. Image quality for tractography and FA maps and ADC maps, interindividual and intraindividual reliability of FA and ADC, and signal-to-noise (SNR) were studied. RESULTS: Both of image qualities with tractography, FA map and ADC map showed that lumbar nerves were more clearly imaged with the rFOV. Intraindividual reliability was higher with rFOV compared with the conventional method for ADC values, while interindividual reliability was higher for both FA values and ADC values with the rFOV method over the conventional method (p < 0.05). Significantly higher SNR was obtained with rFOV compared with cFOV in the spinal canal (p < 0.05). CONCLUSION: rFOV enabled clearer imaging of the lumbar nerve, allowing for more accurate measurement of FA and ADC values. Significantly higher SNR was obtained with rFOV compared with cFOV in the spinal canal. To our knowledge, this research showed for the first time the usefulness of rFOV in patients with degenerative lumbar disorders. High resolution DTI using rFOV may become useful in clinical applications because visualization of nerve entrapments and quantification of DTI parameters may allow more accurate diagnoses of lumbar nerve dysfunction. Advances in knowledge: Compared with traditional methods, rFOV allows for clear imaging of the lumbar nerve and enables accurate measurements of the FA and ADC values. High-resolution DTI with rFOV may be used to visualize nerve entrapments and allow for more accurate diagnosis of DTI parameter quantification with opportunities for clinical applications.
OBJECTIVE: We investigated high resolution diffusion tensor imaging (DTI) of lumbar nerves with reduced field of view (rFOV) using 3 T MRI. METHODS: DTI measured with rFOV was compared with conventional FOV (cFOV) 3.0 T MRI in 5 healthy volunteers and 10 patients with degenerative lumbar disorders. The intracanal, foramina and extraforamina of the L5 nerve were established as the regions of interest and fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values were measured. Image quality for tractography and FA maps and ADC maps, interindividual and intraindividual reliability of FA and ADC, and signal-to-noise (SNR) were studied. RESULTS: Both of image qualities with tractography, FA map and ADC map showed that lumbar nerves were more clearly imaged with the rFOV. Intraindividual reliability was higher with rFOV compared with the conventional method for ADC values, while interindividual reliability was higher for both FA values and ADC values with the rFOV method over the conventional method (p < 0.05). Significantly higher SNR was obtained with rFOV compared with cFOV in the spinal canal (p < 0.05). CONCLUSION:rFOV enabled clearer imaging of the lumbar nerve, allowing for more accurate measurement of FA and ADC values. Significantly higher SNR was obtained with rFOV compared with cFOV in the spinal canal. To our knowledge, this research showed for the first time the usefulness of rFOV in patients with degenerative lumbar disorders. High resolution DTI using rFOV may become useful in clinical applications because visualization of nerve entrapments and quantification of DTI parameters may allow more accurate diagnoses of lumbar nerve dysfunction. Advances in knowledge: Compared with traditional methods, rFOV allows for clear imaging of the lumbar nerve and enables accurate measurements of the FA and ADC values. High-resolution DTI with rFOV may be used to visualize nerve entrapments and allow for more accurate diagnosis of DTI parameter quantification with opportunities for clinical applications.
Authors: Pasquelle K N van der Jagt; Pieter Dik; Martijn Froeling; Thomas C Kwee; Rutger A J Nievelstein; Bennie ten Haken; Alexander Leemans Journal: Neuroimage Date: 2012-06-13 Impact factor: 6.556
Authors: G Zaharchuk; E U Saritas; J B Andre; C T Chin; J Rosenberg; T J Brosnan; A Shankaranarayan; D G Nishimura; N J Fischbein Journal: AJNR Am J Neuroradiol Date: 2011-03-31 Impact factor: 3.825
Authors: B Dallaudière; J Lincot; A Hess; V Balbi; F Cornelis; A Larbi; J-P Laissy; A Cotten; E Schouman-Claeys Journal: Diagn Interv Imaging Date: 2013-10-23 Impact factor: 4.026