| Literature DB >> 28936130 |
Marcella M Gomez1, Mehdi Sadeghpour2, Matthew R Bennett3, Gábor Orosz2, Richard M Murray4.
Abstract
The dynamics of systems with stochastically varying time delays are investigated in this paper. It is shown that the mean dynamics can be used to derive necessary conditions for the stability of equilibria of the stochastic system. Moreover, the second moment dynamics can be used to derive sufficient conditions for almost sure stability of equilibria. The results are summarized using stability charts that are obtained via semi-discretization. The theoretical methods are applied to simple gene regulatory networks where it is demonstrated that stochasticity in the delay can improve the stability of steady protein production.Entities:
Keywords: genetic networks; stability; stochastic delay; systems biology
Year: 2016 PMID: 28936130 PMCID: PMC5603244 DOI: 10.1137/15M1031965
Source DB: PubMed Journal: SIAM J Appl Dyn Syst ISSN: 1536-0040 Impact factor: 2.316