Literature DB >> 2893547

Chromosomal localization of the human proenkephalin and prodynorphin genes.

M Litt1, N E Buroker, S Kondoleon, J Douglass, D Liston, R Sheehy, R E Magenis.   

Abstract

DNA probes derived from rat and human proenkephalin and prodynorphin genes have been used to localize these two opiate neuropeptide genes on human chromosomes. Hybridization of probes to Southern blots made with DNAs from a rodent-human somatic-cell hybrid panel indicates localization of proenkephalin to human chromosome 8 and of prodynorphin to human chromosome 20. In situ hybridization to metaphase chromosomes confirms these assignments and indicates regional localizations of proenkephalin to 8q23-q24 and of prodynorphin to 20p12-pter. A human genomic prodynorphin clone reveals a frequent two-allele TaqI polymorphism.

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Year:  1988        PMID： 2893547      PMCID： PMC1715254     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  28 in total

1.  Four restriction fragment length polymorphisms revealed by probes from a single cosmid map to chromosome 19.

Authors:  L Bufton; G A Bruns; R E Magenis; D Tomar; D Shaw; D Brook; M Litt
Journal:  Am J Hum Genet       Date:  1986-04       Impact factor: 11.025

2.  p380-8A 1.8 SaSs, a single copy clone 5' of c-myc at 8q24 which recognizes an SstI polymorphism.

Authors:  F G Haluska; K Huebner; C M Croce
Journal:  Nucleic Acids Res       Date:  1987-01-26       Impact factor: 16.971

3.  RFLP detected at the 8924 locus by a thyroglobulin cDNA probe.

Authors:  P Simon; H Brocas; C Rodesch; G Vassart
Journal:  Nucleic Acids Res       Date:  1987-01-12       Impact factor: 16.971

4.  Expression of the prodynorphin gene in male and female mammalian reproductive tissues.

Authors:  J Douglass; B Cox; B Quinn; O Civelli; E Herbert
Journal:  Endocrinology       Date:  1987-02       Impact factor: 4.736

5.  Isolation and characterization of DNA probes from a flow-sorted human chromosome 8 library that detect restriction fragment length polymorphism (RFLP).

Authors:  S Wood; T V Starr; R J Shukin
Journal:  Am J Hum Genet       Date:  1986-12       Impact factor: 11.025

6.  Removal of repeated sequences from hybridisation probes.

Authors:  P G Sealey; P A Whittaker; E M Southern
Journal:  Nucleic Acids Res       Date:  1985-03-25       Impact factor: 16.971

7.  DNA restriction fragment analysis of the proopiomelanocortin gene in schizophrenia and bipolar disorders.

Authors:  J Feder; H M Gurling; J Darby; L L Cavalli-Sforza
Journal:  Am J Hum Genet       Date:  1985-03       Impact factor: 11.025

8.  Four restriction fragment length polymorphisms revealed by probes from a single cosmid map to human chromosome 12q.

Authors:  N E Buroker; R E Magenis; K Weliky; G Bruns; M Litt
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

9.  A highly polymorphic locus in human DNA revealed by cosmid-derived probes.

Authors:  M Litt; R L White
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

10.  Dynorphin- and enkephalin-like immunoreactivity is altered in limbic-basal ganglia regions of rat brain after repeated electroconvulsive shock.

Authors:  T Kanamatsu; J F McGinty; C L Mitchell; J S Hong
Journal:  J Neurosci       Date:  1986-03       Impact factor: 6.167
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  10 in total

1.  Dinucleotide repeat polymorphism at the D2S72 locus.

Authors:  J L Weber; P E May
Journal:  Nucleic Acids Res       Date:  1990-04-25       Impact factor: 16.971

2.  Rapid RFLP screening using DNA from complete hydatidiform moles.

Authors:  M Litt; A Buder; U Surti
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

3.  A frequent RFLP identified by a human proenkephalin genomic clone [HGM9 symbol PENK].

Authors:  M Litt; A Buder
Journal:  Nucleic Acids Res       Date:  1989-01-11       Impact factor: 16.971

Review 4.  Human chromosome 8.

Authors:  S Wood
Journal:  J Med Genet       Date:  1988-11       Impact factor: 6.318

Review 5.  The transcriptional regulation of the preproenkephalin gene.

Authors:  G Weisinger
Journal:  Biochem J       Date:  1995-05-01       Impact factor: 3.857

6.  Genetic linkage analysis of manic depression in Iceland.

Authors:  D Curtis; R Sherrington; P Brett; D S Holmes; G Kalsi; J Brynjolfsson; H Petursson; L Rifkin; P Murphy; E Moloney
Journal:  J R Soc Med       Date:  1993-09       Impact factor: 5.344

7.  Protein-DNA interactions during phenotypic differentiation.

Authors:  A L Dobi; M Palkovits; C G Palkovits; E Santha; D van Agoston
Journal:  Mol Neurobiol       Date:  1995 Apr-Jun       Impact factor: 5.590

8.  Localization of the gene for human proliferating nuclear antigen/cyclin by in situ hybridization.

Authors:  G Webb; P Parsons; G Chenevix-Trench
Journal:  Hum Genet       Date:  1990-11       Impact factor: 4.132

9.  Evaluation of prodynorphin gene polymorphisms and their association with heroin addiction in a sample of the southeast Iranian population.

Authors:  Mohammad Hashemi; Mansour Shakiba; Sara Sanaei; Ghazaleh Shahkar; Maryam Rezaei; Azizolla Mojahed; Gholamreza Bahari
Journal:  Mol Biol Res Commun       Date:  2018-03

10.  Association between prodynorphin gene polymorphisms and opioid dependence susceptibility: a meta-analysis.

Authors:  Chang-Wang Wang; Min Ma; Wei-Guang Lu; Ru-Qin Luo
Journal:  BMC Psychiatry       Date:  2019-09-11       Impact factor: 3.630
  10 in total

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