BACKGROUND: The incidence of meningioma has increased drastically recently, particularly in older adults. Surgical intervention has the potential to reduce neurologic symptoms and achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes after meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications after craniotomy for resection of meningioma. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was used to identify patients undergoing craniotomy for meningioma resection between 2005 and 2012. Multivariate analysis was used to identify associations between age and postoperative complications. RESULTS: Age >80 years is an independent risk factor for any complication (odds ratio [OR], 2.374; 95% confidence interval [CI], 1.3-4.4; P = 0.015), death within 30 days of surgery (OR, 15.7; 95% CI, 3.0-81.0; P < 0.001), and length of stay >5 days (OR, 3.2; 95% CI, 1.8-5.6; P < 0.001). CONCLUSIONS: Advanced age, particularly >80 years, is an independent predictor of morbidity and mortality in patients undergoing craniotomy for resection of meningioma. As such, it should be considered in preoperative optimization and risk stratification.
BACKGROUND: The incidence of meningioma has increased drastically recently, particularly in older adults. Surgical intervention has the potential to reduce neurologic symptoms and achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcomes after meningioma surgery. The objective of this study was to identify the relationship between age and postoperative complications after craniotomy for resection of meningioma. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was used to identify patients undergoing craniotomy for meningioma resection between 2005 and 2012. Multivariate analysis was used to identify associations between age and postoperative complications. RESULTS: Age >80 years is an independent risk factor for any complication (odds ratio [OR], 2.374; 95% confidence interval [CI], 1.3-4.4; P = 0.015), death within 30 days of surgery (OR, 15.7; 95% CI, 3.0-81.0; P < 0.001), and length of stay >5 days (OR, 3.2; 95% CI, 1.8-5.6; P < 0.001). CONCLUSIONS: Advanced age, particularly >80 years, is an independent predictor of morbidity and mortality in patients undergoing craniotomy for resection of meningioma. As such, it should be considered in preoperative optimization and risk stratification.
Authors: Michael Spadola; Ali S Farooqi; Austin J Borja; Ryan Dimentberg; Rachel Blue; Kaitlyn Shultz; Scott D McClintock; Neil R Malhotra Journal: Cureus Date: 2022-04-26
Authors: Georg Alexander Gihr; Diana Horvath-Rizea; Nikita Garnov; Patricia Kohlhof-Meinecke; Oliver Ganslandt; Hans Henkes; Hans Jonas Meyer; Karl-Titus Hoffmann; Alexey Surov; Stefan Schob Journal: Mol Imaging Biol Date: 2018-08 Impact factor: 3.488
Authors: Yang Yang; Anna M Zeitlberger; Marian C Neidert; Victor E Staartjes; Morgan Broggi; Costanza Maria Zattra; Flavio Vasella; Julia Velz; Jiri Bartek; Alexander Fletcher-Sandersjöö; Petter Förander; Darius Kalasauskas; Mirjam Renovanz; Florian Ringel; Konstantin R Brawanski; Johannes Kerschbaumer; Christian F Freyschlag; Asgeir S Jakola; Kristin Sjåvik; Ole Solheim; Bawarjan Schatlo; Alexandra Sachkova; Hans Christoph Bock; Abdelhalim Hussein; Veit Rohde; Marike L D Broekman; Claudine O Nogarede; Cynthia M C Lemmens; Julius M Kernbach; Georg Neuloh; Niklaus Krayenbühl; Paolo Ferroli; Luca Regli; Oliver Bozinov; Martin N Stienen Journal: Brain Spine Date: 2021-10-21