Literature DB >> 28917398

Hydrogel ocular sealant for clear corneal incisions in cataract surgery.

Nambi Nallasamy1, Karen E Grove1, Gary L Legault1, Melissa B Daluvoy1, Terry Kim2.   

Abstract

PURPOSE: To assess the relationship between use of a hydrogel ocular sealant (Resure) to secure clear corneal incisions (CCIs) in cataract surgery and surgeon efficiency, patient symptomatology, and postoperative results.
SETTING: Duke University Eye Center, Durham, North Carolina, USA.
DESIGN: Retrospective case series.
METHODS: A 1:1 matched cohort of hydrogel sealant exposure-discordant eyes of cataract surgery patients was retrospectively generated. Consecutive patients who had bilateral cataract surgery during the study period and in whom the hydrogel sealant was used to secure the CCI in only 1 of the 2 eyes were included in the study. The relationship between use of the hydrogel sealant and surgical time, 1-day postoperative foreign-body sensation, clinically noted corneal edema, and intraocular pressure (IOP) was evaluated.
RESULTS: Ninety eyes of 45 patients were included in the study. One day postoperatively, no wound leak was found in any eye; the sealant was noted to be out of place in 2 (4.4%) of 45 cases. No statistically significant difference was found between sealant and non-sealant eyes in total surgical time (P = .16) or in IOP (P = .55), corneal edema (P = 1.00), or foreign-body sensation (P = .38) 1 day postoperatively.
CONCLUSION: The hydrogel sealant was not observed to affect duration of surgery or 1-day postoperative IOP, corneal edema, or foreign-body sensation.
Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28917398     DOI: 10.1016/j.jcrs.2017.05.035

Source DB:  PubMed          Journal:  J Cataract Refract Surg        ISSN: 0886-3350            Impact factor:   3.351


  5 in total

Review 1.  Hydrogel-based ocular drug delivery systems: Emerging fabrication strategies, applications, and bench-to-bedside manufacturing considerations.

Authors:  Remy C Cooper; Hu Yang
Journal:  J Control Release       Date:  2019-05-22       Impact factor: 9.776

2.  Development and characterization of a hydrogel-based adhesive patch for sealing open-globe injuries.

Authors:  Clotilde Jumelle; Ann Yung; Ehsan Shirzaei Sani; Yukako Taketani; Fanny Gantin; Louisa Bourel; Shudan Wang; Erdem Yüksel; Senne Seneca; Nasim Annabi; Reza Dana
Journal:  Acta Biomater       Date:  2021-10-19       Impact factor: 8.947

3.  Hydrogel Sealant for Closure of Clear Corneal Incisions in Combined Glaucoma Procedures.

Authors:  Ryan D Machiele; Abhilash Guduru; Leon W Herndon
Journal:  Clin Ophthalmol       Date:  2022-03-19

4.  Burst Pressures in Eyes with Clear Corneal Incisions Treated with ReSure Glue.

Authors:  Ahmed E M Shehata; Siva P Kambhampati; Jiangxia Wang; Uri S Soiberman
Journal:  J Ophthalmol       Date:  2021-02-04       Impact factor: 1.909

5.  In situ-forming collagen hydrogel crosslinked via multi-functional PEG as a matrix therapy for corneal defects.

Authors:  Gabriella Maria Fernandes-Cunha; Karen Mei Chen; Fang Chen; Peter Le; Ju Hee Han; Leela Ann Mahajan; Hyun Jong Lee; Kyung Sun Na; David Myung
Journal:  Sci Rep       Date:  2020-10-07       Impact factor: 4.996

  5 in total

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