Literature DB >> 2891551

The effect of neuropeptide Y (NPY) on stimulation-evoked release of [3H]norepinephrine (NE) from rat hypothalamic and cerebral cortical slices.

H Yokoo1, D H Schlesinger, M Goldstein.   

Abstract

The effects of neuropeptide Y (NPY) on stimulation-evoked release of [3H]norepinephrine ([3H]NE) in rat hypothalamic and cerebral cortical slices were investigated. NPY inhibits the stimulation-evoked release of [3H]NE from hypothalamic, but not from cerebral cortical slices. NPY potentiates the inhibition of [3H]NE release by the alpha 2-agonist UK 14,304 in the hypothalamic slices. The blockade of alpha 2-adrenoceptors by RX 781094 diminishes the inhibitory effects of NPY. These results suggest that in the hypothalamic slices the action of NPY might be in part mediated by the alpha 2-adrenoceptors.

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Year:  1987        PMID： 2891551     DOI： 10.1016/0014-2999(87)90545-0

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  7 in total

1.  Serotonin release in the rat brain cortex is inhibited by neuropeptide Y but not affected by ACTH1-24, angiotensin II, bradykinin and delta-sleep-inducing peptide.

Authors:  E Schlicker; G Gross; K Fink; T Glaser; M Göthert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-02       Impact factor: 3.000

2.  Neuropeptide Y perfused in the preoptic area of rats shifts extracellular efflux of dopamine, norepinephrine, and serotonin during hypothermia and feeding.

Authors:  R D Myers; M F Lankford; A K Roscoe
Journal:  Neurochem Res       Date:  1996-06       Impact factor: 3.996

3.  Neuropeptide Y depresses GABA-mediated calcium transients in developing suprachiasmatic nucleus neurons: a novel form of calcium long-term depression.

Authors:  K Obrietan; A N van den Pol
Journal:  J Neurosci       Date:  1996-05-15       Impact factor: 6.167

4.  Depression by neuropeptide Y of noradrenergic inhibitory postsynaptic potentials of locus coeruleus neurones.

Authors:  E P Finta; J T Regenold; P Illes
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-10       Impact factor: 3.000

Review 5.  Neuroendocrine regulation of thyrotropin-releasing hormone (TRH) in the tuberoinfundibular system.

Authors:  R Toni; R M Lechan
Journal:  J Endocrinol Invest       Date:  1993-10       Impact factor: 4.256

6.  Neuropeptide Y potentiates via Y2-receptors the inhibitory effect of noradrenaline in rat locus coeruleus neurones.

Authors:  P Illes; E P Finta; K Nieber
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-11       Impact factor: 3.000

7.  Enhanced inhibitory control by neuropeptide Y Y5 receptor blockade in rats.

Authors:  A Bari; A Dec; A W Lee; J Lee; D Song; E Dale; J Peterson; S Zorn; X Huang; B Campbell; T W Robbins; A R West
Journal:  Psychopharmacology (Berl)       Date:  2014-09-07       Impact factor: 4.530
  7 in total

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