Therapeutic results in cryptorchidism after combination therapy with LH-RH nasal spray and hCG.

Seventy-two boys with 81 cryptorchid testes were treated with combined LH-RH nasal spray and hCG in the period between 1983 and 1985. Cryptocur (LH-RH) was applied as nasal spray at a dose of 1.2 mg daily over a period of 14 days. In all of the patients, hCG treatment was carried out subsequently according to the WHO guidelines with five intramuscular injections at 2-day intervals. Primary treatment results considerably improved using the regimen. The rate of complete descent was 86.4% at the end of therapy and later dropped to 70.6% after 2 years follow-up. These results support the experience of Hadziselimovic et al. with this combined treatment.