Literature DB >> 28913659

Will Gay and Bisexual Men Taking Oral Pre-exposure Prophylaxis (PrEP) Switch to Long-Acting Injectable PrEP Should It Become Available?

Steven A John1, Thomas H F Whitfield1,2, H Jonathon Rendina1,2,3, Jeffrey T Parsons1,2,3, Christian Grov4.   

Abstract

Oral pre-exposure prophylaxis (PrEP) is highly effective at reducing HIV transmission risk and is CDC recommended for many gay, bisexual, and other men who have sex with men (GBM). We sought to investigate awareness of and preference for using long-acting injectable PrEP (LAI-PrEP) among GBM currently taking oral PrEP (n = 104), and identify their concerns. About half of GBM had heard of LAI-PrEP, and 30.8% specifically preferred LAI-PrEP. GBM with more concerns about the level of protection and drug half-life of LAI-PrEP had lower odds of preferring LAI-PrEP. Given that daily pill adherence is a challenge for some on PrEP, it is important to investigate the degree to which those on PrEP might consider LAI-PrEP as an alternative.

Entities:  

Keywords:  HIV; Long-acting injectable; Men who have sex with men; Pre-exposure prophylaxis

Mesh:

Substances:

Year:  2018        PMID: 28913659      PMCID: PMC5851796          DOI: 10.1007/s10461-017-1907-2

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  8 in total

Review 1.  CROI 2016: Hot Spots in HIV Infection and Advances in HIV Prevention.

Authors:  Susan P Buchbinder; Albert Y Liu
Journal:  Top Antivir Med       Date:  2016 May-Jun

2.  Estimating populations of men who have sex with men in the southern United States.

Authors:  Spencer Lieb; Daniel R Thompson; Shyam Misra; Gary J Gates; Wayne A Duffus; Stephen J Fallon; Thomas M Liberti; Evelyn M Foust; Robert M Malow
Journal:  J Urban Health       Date:  2009-11       Impact factor: 3.671

3.  Uptake of HIV Pre-Exposure Prophylaxis (PrEP) in a National Cohort of Gay and Bisexual Men in the United States.

Authors:  Jeffrey T Parsons; H Jonathon Rendina; Jonathan M Lassiter; Thomas H F Whitfield; Tyrel J Starks; Christian Grov
Journal:  J Acquir Immune Defic Syndr       Date:  2017-03-01       Impact factor: 3.731

4.  Familiarity with and Preferences for Oral and Long-Acting Injectable HIV Pre-exposure Prophylaxis (PrEP) in a National Sample of Gay and Bisexual Men in the U.S.

Authors:  Jeffrey T Parsons; H Jonathon Rendina; Thomas H F Whitfield; Christian Grov
Journal:  AIDS Behav       Date:  2016-07

5.  Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men.

Authors:  George J Greene; Greg Swann; Angela J Fought; Alex Carballo-Diéguez; Thomas J Hope; Patrick F Kiser; Brian Mustanski; Richard T D'Aquila
Journal:  AIDS Behav       Date:  2017-05

6.  Preferences for daily or intermittent pre-exposure prophylaxis regimens and ability to anticipate sex among HIV uninfected members of Kenyan HIV serodiscordant couples.

Authors:  Sarah T Roberts; Renee Heffron; Kenneth Ngure; Connie Celum; Ann Kurth; Kathryn Curran; Nelly Mugo; Jared M Baeten
Journal:  AIDS Behav       Date:  2014-09

7.  From efficacy to effectiveness: facilitators and barriers to PrEP acceptability and motivations for adherence among MSM and transgender women in New York City.

Authors:  Sarit A Golub; Kristi E Gamarel; H Jonathon Rendina; Anthony Surace; Corina L Lelutiu-Weinberger
Journal:  AIDS Patient Care STDS       Date:  2013-04       Impact factor: 5.078

8.  High interest in a long-acting injectable formulation of pre-exposure prophylaxis for HIV in young men who have sex with men in NYC: a P18 cohort substudy.

Authors:  Kathrine Meyers; Kristina Rodriguez; Robert W Moeller; Ilana Gratch; Martin Markowitz; Perry N Halkitis
Journal:  PLoS One       Date:  2014-12-11       Impact factor: 3.240

  8 in total
  22 in total

1.  A missing perspective: injectable pre-exposure prophylaxis for people who inject drugs.

Authors:  K B Biello; A Edeza; P Salhaney; D L Biancarelli; M J Mimiaga; M L Drainoni; E S Childs; A R Bazzi
Journal:  AIDS Care       Date:  2019-03-01

2.  Decisional Balance and Contemplation Ladder to Support Interventions for HIV Pre-Exposure Prophylaxis Uptake and Persistence.

Authors:  Steven A John; H Jonathon Rendina; Tyrel J Starks; Christian Grov; Jeffrey T Parsons
Journal:  AIDS Patient Care STDS       Date:  2019-01-17       Impact factor: 5.078

3.  Health Care Provider Barriers to HIV Pre-Exposure Prophylaxis in the United States: A Systematic Review.

Authors:  Benedikt Pleuhs; Katherine G Quinn; Jennifer L Walsh; Andrew E Petroll; Steven A John
Journal:  AIDS Patient Care STDS       Date:  2020-02-28       Impact factor: 5.078

4.  Projected Impact of Concurrently Available Long-Acting Injectable and Daily-Oral Human Immunodeficiency Virus Preexposure Prophylaxis: A Mathematical Model.

Authors:  Kevin M Maloney; Adrien Le Guillou; Robert A Driggers; Supriya Sarkar; Emeli J Anderson; Amyn A Malik; Samuel M Jenness
Journal:  J Infect Dis       Date:  2021-01-04       Impact factor: 5.226

5.  Why I Quit Pre-Exposure Prophylaxis (PrEP)? A Mixed-Method Study Exploring Reasons for PrEP Discontinuation and Potential Re-initiation Among Gay and Bisexual Men.

Authors:  Thomas H F Whitfield; Steven A John; H Jonathon Rendina; Christian Grov; Jeffrey T Parsons
Journal:  AIDS Behav       Date:  2018-11

6.  Human Immunodeficiency Virus/Sexually Transmitted Infection Counseling and Testing Services Received by Gay and Bisexual Men Using Preexposure Prophylaxis at Their Last PrEP Care Visit.

Authors:  Jeffrey T Parsons; Steven A John; Thomas H F Whitfield; Jorge Cienfuegos-Szalay; Christian Grov
Journal:  Sex Transm Dis       Date:  2018-12       Impact factor: 2.830

7.  Next-Generation HIV Pre-Exposure Prophylaxis Preferences Among Men Who Have Sex with Men Taking Daily Oral Pre-Exposure Prophylaxis.

Authors:  Jacqueline Ellison; Jacob J van den Berg; Madeline C Montgomery; Jun Tao; Rashmi Pashankar; Matthew J Mimiaga; Philip A Chan
Journal:  AIDS Patient Care STDS       Date:  2019-10-11       Impact factor: 5.078

8.  Correlates of PrEP Uptake Among Young Sexual Minority Men and Transgender Women in New York City: The Need to Reframe "Risk" Messaging and Normalize Preventative Health.

Authors:  J Jaiswal; C LoSchiavo; S Meanley; K Hascher; A B Cox; K B Dunlap; S N Singer; P N Halkitis
Journal:  AIDS Behav       Date:  2021-04-08

9.  Insurance- and medical provider-related barriers and facilitators to staying on PrEP: results from a qualitative study.

Authors:  Alexa B D'Angelo; Javier Lopez-Rios; Anthony W P Flynn; Ian W Holloway; David W Pantalone; Christian Grov
Journal:  Transl Behav Med       Date:  2021-03-16       Impact factor: 3.046

10.  Interest in Long-Acting Injectable Pre-exposure Prophylaxis (LAI PrEP) Among Women in the Women's Interagency HIV Study (WIHS): A Qualitative Study Across Six Cities in the United States.

Authors:  Morgan M Philbin; Carrigan Parish; Elizabeth N Kinnard; Sarah E Reed; Deanna Kerrigan; Maria L Alcaide; Mardge H Cohen; Oluwakemi Sosanya; Anandi N Sheth; Adaora A Adimora; Jennifer Cocohoba; Lakshmi Goparaju; Elizabeth T Golub; Margaret Fischl; Lisa R Metsch
Journal:  AIDS Behav       Date:  2021-03
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