Literature DB >> 28905179

Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries.

Matthew L Maciejewski1,2, Xiaojuan Mi3, Jeremy Sussman4,5, Melissa Greiner3, Lesley H Curtis6,3, Judy Ng7, Samuel C Haffer8, Eve A Kerr4,5.   

Abstract

BACKGROUND: Deintensification of diabetic therapy is often clinically appropriate for older adults, because the benefit of aggressive diabetes treatment declines with age, while the risks increase.
OBJECTIVE: We examined rates of overtreatment and deintensification of therapy for older adults with diabetes, and whether these rates differed by medical, demographic, and socioeconomic characteristics. DESIGN, SUBJECTS, AND MAIN MEASURES: We analyzed Medicare claims data from 10 states, linked to outpatient laboratory values to identify patients potentially overtreated for diabetes (HbA1c < 6.5% with fills for any diabetes medications beyond metformin, 1/1/2011-6/30/2011). We examined characteristics associated with deintensification for potentially overtreated diabetic patients. We used multinomial logistic regression to examine whether patient characteristics associated with overtreatment of diabetes differed from those associated with undertreatment (i.e. HbA1c > 9.0%). KEY
RESULTS: Of 78,792 Medicare recipients with diabetes, 8560 (10.9%) were potentially overtreated. Overtreatment of diabetes was more common among those who were over 75 years of age and enrolled in Medicaid (p < 0.001), and was less common among Hispanics (p = 0.009). Therapy was deintensified for 14% of overtreated diabetics. Appropriate deintensification of diabetic therapy was more common for patients with six or more chronic conditions, more outpatient visits, or living in urban areas; deintensification was less common for those over age 75. Only 6.9% of Medicare recipients with diabetes were potentially undertreated. Variables associated with overtreatment of diabetes differed from those associated with undertreatment.
CONCLUSIONS: Medicare recipients are more frequently overtreated than undertreated for diabetes. Medicare recipients who are overtreated for diabetes rarely have their regimens deintensified.

Entities:  

Keywords:  Medicare; beneficiary; deintensification; diabetes; potential overtreatment

Mesh:

Substances:

Year:  2017        PMID: 28905179      PMCID: PMC5756160          DOI: 10.1007/s11606-017-4167-y

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  32 in total

1.  Intensive Treatment and Severe Hypoglycemia Among Adults With Type 2 Diabetes.

Authors:  Rozalina G McCoy; Kasia J Lipska; Xiaoxi Yao; Joseph S Ross; Victor M Montori; Nilay D Shah
Journal:  JAMA Intern Med       Date:  2016-07-01       Impact factor: 21.873

Review 2.  'Choosing Wisely': a growing international campaign.

Authors:  Wendy Levinson; Marjon Kallewaard; R Sacha Bhatia; Daniel Wolfson; Sam Shortt; Eve A Kerr
Journal:  BMJ Qual Saf       Date:  2014-12-31       Impact factor: 7.035

Review 3.  Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes: a meta-analysis.

Authors:  Julienne K Kirk; Ralph B D'Agostino; Ronny A Bell; Leah V Passmore; Denise E Bonds; Andrew J Karter; K M Venkat Narayan
Journal:  Diabetes Care       Date:  2006-09       Impact factor: 19.112

4.  Identifying chronic conditions in Medicare claims data: evaluating the Chronic Condition Data Warehouse algorithm.

Authors:  Yelena Gorina; Ellen A Kramarow
Journal:  Health Serv Res       Date:  2011-06-07       Impact factor: 3.402

5.  Ethnic and racial differences in diabetes care: The Insulin Resistance Atherosclerosis Study.

Authors:  Denise E Bonds; Daniel J Zaccaro; Andrew J Karter; Joe V Selby; Mohammed Saad; David C Goff
Journal:  Diabetes Care       Date:  2003-04       Impact factor: 19.112

6.  Assessing potential glycemic overtreatment in persons at hypoglycemic risk.

Authors:  Chin-Lin Tseng; Orysya Soroka; Miriam Maney; David C Aron; Leonard M Pogach
Journal:  JAMA Intern Med       Date:  2014-02-01       Impact factor: 21.873

7.  Racial and ethnic disparities among enrollees in Medicare Advantage plans.

Authors:  John Z Ayanian; Bruce E Landon; Joseph P Newhouse; Alan M Zaslavsky
Journal:  N Engl J Med       Date:  2014-12-11       Impact factor: 91.245

8.  Self-report of hypoglycemia and health-related quality of life in patients with type 1 and type 2 diabetes.

Authors:  Rozalina G McCoy; Holly K Van Houten; Jeanette Y Ziegenfuss; Nilay D Shah; Robert A Wermers; Steven A Smith
Journal:  Endocr Pract       Date:  2013 Sep-Oct       Impact factor: 3.443

9.  Racial disparities in diabetes care processes, outcomes, and treatment intensity.

Authors:  Michele Heisler; Dylan M Smith; Rodney A Hayward; Sarah L Krein; Eve A Kerr
Journal:  Med Care       Date:  2003-11       Impact factor: 2.983

10.  Increased mortality of patients with diabetes reporting severe hypoglycemia.

Authors:  Rozalina G McCoy; Holly K Van Houten; Jeanette Y Ziegenfuss; Nilay D Shah; Robert A Wermers; Steven A Smith
Journal:  Diabetes Care       Date:  2012-06-14       Impact factor: 19.112

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  14 in total

1.  Personalized medicine and proper dosage: Over- and undertreatment of chronic diseases endanger patients' health and strain public health systems.

Authors:  Anthi Trasta
Journal:  EMBO Rep       Date:  2018-02-27       Impact factor: 8.807

Review 2.  Approaches to Risk Assessment Among Older Patients With Diabetes.

Authors:  Scott J Pilla; Nancy L Schoenborn; Nisa M Maruthur; Elbert S Huang
Journal:  Curr Diab Rep       Date:  2019-07-19       Impact factor: 4.810

3.  Deintensification of Diabetes Medications among Veterans at the End of Life in VA Nursing Homes.

Authors:  Joshua D Niznik; Jacob N Hunnicutt; Xinhua Zhao; Maria K Mor; Florentina Sileanu; Sherrie L Aspinall; Sydney P Springer; Mary J Ersek; Walid F Gellad; Loren J Schleiden; Joseph T Hanlon; Joshua M Thorpe; Carolyn T Thorpe
Journal:  J Am Geriatr Soc       Date:  2020-02-17       Impact factor: 5.562

4.  Control of glycemia and blood pressure in British adults with diabetes mellitus and subsequent therapy choices: a comparison across health states.

Authors:  Finlay A McAlister; Brendan Cord Lethebe; Caitlin Lambe; Tyler Williamson; Mark Lowerison
Journal:  Cardiovasc Diabetol       Date:  2018-02-12       Impact factor: 9.951

5.  Simplifying Complex Insulin Regimens While Preserving Good Glycemic Control in Type 2 Diabetes.

Authors:  Zoltán Taybani; Balázs Bótyik; Mónika Katkó; András Gyimesi; Tamás Várkonyi
Journal:  Diabetes Ther       Date:  2019-07-25       Impact factor: 2.945

6.  Paradox of glycemic management: multimorbidity, glycemic control, and high-risk medication use among adults with diabetes.

Authors:  Rozalina G McCoy; Kasia J Lipska; Holly K Van Houten; Nilay D Shah
Journal:  BMJ Open Diabetes Res Care       Date:  2020-02

7.  De-Intensification Of Blood Glucose Lowering Medication In People Identified As Being Over-Treated: A Mixed Methods Study.

Authors:  Huberta E Hart; Kim Ditzel; Guy E Rutten; Esther de Groot; Samuel Seidu; Kamlesh Khunti; Rimke C Vos
Journal:  Patient Prefer Adherence       Date:  2019-10-18       Impact factor: 2.711

8.  Developing Strategies to Reduce Unnecessary Services in Primary Care: Protocol for User-Centered Design Charrettes.

Authors:  Mandi L Klamerus; Laura J Damschroder; Jordan B Sparks; Sarah E Skurla; Eve A Kerr; Timothy P Hofer; Tanner J Caverly
Journal:  JMIR Res Protoc       Date:  2019-11-26

9.  Validation of Risk Equations for Complications of Type 2 Diabetes (RECODe) Using Individual Participant Data From Diverse Longitudinal Cohorts in the U.S.

Authors:  Sanjay Basu; Jeremy B Sussman; Seth A Berkowitz; Rodney A Hayward; Alain G Bertoni; Adolfo Correa; Stanford Mwasongwe; John S Yudkin
Journal:  Diabetes Care       Date:  2017-12-21       Impact factor: 19.112

10.  Natural Language Processing Improves Detection of Nonsevere Hypoglycemia in Medical Records Versus Coding Alone in Patients With Type 2 Diabetes but Does Not Improve Prediction of Severe Hypoglycemia Events: An Analysis Using the Electronic Medical Record in a Large Health System.

Authors:  Anita D Misra-Hebert; Alex Milinovich; Alex Zajichek; Xinge Ji; Todd D Hobbs; Wayne Weng; Paul Petraro; Sheldon X Kong; Michelle Mocarski; Rahul Ganguly; Janine M Bauman; Kevin M Pantalone; Robert S Zimmerman; Michael W Kattan
Journal:  Diabetes Care       Date:  2020-05-15       Impact factor: 19.112

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