| Literature DB >> 2889747 |
J Pivonka1, F H Segelman, C A Hartman, W E Segl, N Kucharczyk, R D Sofia.
Abstract
A manual-injection liquid chromatographic method using fluorescence detection permitted determination of a new antiasthmatic drug, azelastine, and its desmethyl metabolite extracted from human plasma. Reliable quantitation was achieved to at least 0.3 ng/ml for each analyte. No interference was seen in co-chromatography of sixteen other substances, which were potential co-medications (or their metabolites) as used in standard asthma or allergy treatment.Entities:
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Year: 1987 PMID: 2889747 DOI: 10.1016/0378-4347(87)80158-5
Source DB: PubMed Journal: J Chromatogr