Literature DB >> 28893566

Does fear extinction in the laboratory predict outcomes of exposure therapy? A treatment analog study.

Eduard Forcadell1, David Torrents-Rodas2, Bram Vervliet3, David Leiva4, Miquel Tortella-Feliu5, Miquel A Fullana6.   

Abstract

Fear extinction models have a key role in our understanding of anxiety disorders and their treatment with exposure therapy. Here, we tested whether individual differences in fear extinction learning and fear extinction recall in the laboratory were associated with the outcomes of an exposure therapy analog (ETA). Fifty adults with fear of spiders participated in a two-day fear-learning paradigm assessing fear extinction learning and fear extinction recall, and then underwent a brief ETA. Correlational analyses indicated that enhanced extinction learning was associated with better ETA outcome. Our results partially support the idea that individual differences in fear extinction learning may be associated with exposure therapy outcome, but suggest that further research in this area is needed.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anxiety disorders; Exposure therapy; Extinction learning; Extinction recall; Fear conditioning; Fear learning

Mesh:

Year:  2017        PMID: 28893566     DOI: 10.1016/j.ijpsycho.2017.09.001

Source DB:  PubMed          Journal:  Int J Psychophysiol        ISSN: 0167-8760            Impact factor:   2.997


  10 in total

1.  Neural responses during extinction learning predict exposure therapy outcome in phobia: results from a randomized-controlled trial.

Authors:  Iris Lange; Liesbet Goossens; Stijn Michielse; Jindra Bakker; Bram Vervliet; Machteld Marcelis; Marieke Wichers; Jim van Os; Therese van Amelsvoort; Koen Schruers
Journal:  Neuropsychopharmacology       Date:  2019-07-28       Impact factor: 7.853

2.  Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies.

Authors:  Thomas G Adams; Josh M Cisler; Benjamin Kelmendi; Jamilah R George; Stephen A Kichuk; Christopher L Averill; Alan Anticevic; Chadi G Abdallah; Christopher Pittenger
Journal:  Depress Anxiety       Date:  2021-08-31       Impact factor: 6.505

3.  Effects of intranasal insulin as an enhancer of fear extinction: a randomized, double-blind, placebo-controlled experimental study.

Authors:  Diana S Ferreira de Sá; Sonja Römer; Alexandra H Brückner; Tobias Issler; Alexander Hauck; Tanja Michael
Journal:  Neuropsychopharmacology       Date:  2020-01-02       Impact factor: 7.853

4.  Extinction of Conditioned Fear in Adolescents and Adults: A Human fMRI Study.

Authors:  Despina E Ganella; Katherine D Drummond; Eleni P Ganella; Sarah Whittle; Jee Hyun Kim
Journal:  Front Hum Neurosci       Date:  2018-01-08       Impact factor: 3.169

5.  Validating the use of a smartphone app for remote administration of a fear conditioning paradigm.

Authors:  K L Purves; E Constantinou; T McGregor; K J Lester; T J Barry; M Treanor; M Sun; J Margraf; M G Craske; G Breen; T C Eley
Journal:  Behav Res Ther       Date:  2019-09-12

6.  Individual differences in fear acquisition: multivariate analyses of different emotional negativity scales, physiological responding, subjective measures, and neural activation.

Authors:  Rachel Sjouwerman; Robert Scharfenort; Tina B Lonsdorf
Journal:  Sci Rep       Date:  2020-09-17       Impact factor: 4.379

Review 7.  Is there a neuroscience-based, mechanistic rationale for transcranial direct current stimulation as an adjunct treatment for posttraumatic stress disorder?

Authors:  C R Faucher; R A Doherty; N S Philip; A S M Harle; J J E Cole; M Van't Wout-Frank
Journal:  Behav Neurosci       Date:  2021-08-02       Impact factor: 1.912

8.  Attentional Control and Fear Extinction in Subclinical Fear: An Exploratory Study.

Authors:  Eduard Forcadell; David Torrents-Rodas; Devi Treen; Miquel A Fullana; Miquel Tortella-Feliu
Journal:  Front Psychol       Date:  2017-09-26

Review 9.  Rodent models of impaired fear extinction.

Authors:  Nicolas Singewald; Andrew Holmes
Journal:  Psychopharmacology (Berl)       Date:  2018-10-31       Impact factor: 4.530

10.  Stimulus-Based Extinction Generalization: Neural Correlates and Modulation by Cortisol.

Authors:  Bianca Hagedorn; Oliver T Wolf; Christian J Merz
Journal:  Int J Neuropsychopharmacol       Date:  2021-04-21       Impact factor: 5.176

  10 in total

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