| Literature DB >> 28889732 |
Min-Hsiung Pan1, Jia-Ching Wu1, Chi-Tang Ho1, Vladimir Badmaev1.
Abstract
Background Immunity and Longevity Methods A water extract of Curcuma longa (L.) [vern. Turmeric] roots (TurmericImmune™) standardized for a minimum 20 % of turmeric polysaccharides ukonan A, B, C and D was evaluated for its biological properties in in vitro tissue culture studies. Results The water extract of turmeric (TurP) exhibited induced-nitric oxide (NO) production in RAW264.7 macrophages. These results suggested the immunomodulatory effects of TurP. In addition, the polysaccharides up-regulated function of telomerase reverse transcriptase (TERT) equally to the phenolic compound from turmeric, curcumin. Conclusions The ukonan family of polysaccharides may assist in promoting cellular immune responses, tissue repair and lifespan by enhancing immune response and telomere function.Entities:
Keywords: TurmericImmune; immunity; phenolic and curcumin; telomerase reverse transcriptase (TERT); telomere; turmeric; ukonan
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Year: 2017 PMID： 28889732 DOI： 10.1515/jcim-2015-0107
Source DB: PubMed Journal: J Complement Integr Med ISSN： 1553-3840