| Literature DB >> 28886763 |
Ke Zhang1, Ning Zhang1, Michael D Weir2, Mark A Reynolds2, Yuxing Bai3, Hockin H K Xu4.
Abstract
Current dental restorative materials are typically inert and replace missing tooth structures. This article reviews efforts in the development of a new generation of bioactive materials designed to not only replace the missing tooth volume but also possess therapeutic functions. Composites and bonding agents with remineralizing and antibacterial characteristics have shown promise in replacing lost minerals, inhibiting recurrent caries, neutralizing acids, repelling proteins, and suppressing biofilms and acid production. Furthermore, they have demonstrated a low cytotoxicity similar to current resins, with additional benefits to protect the dental pulp and promote tertiary dentin formation. This new class of bioactive materials shows promise in reversing lesions and inhibiting caries.Entities:
Keywords: Antibacterial monomers; Bioactive composites; Bonding agents; Calcium phosphate nanoparticles; Caries inhibition; Oral biofilms; Remineralization; Silver nanoparticles
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Year: 2017 PMID： 28886763 PMCID： PMC5803788 DOI： 10.1016/j.cden.2017.05.002
Source DB: PubMed Journal: Dent Clin North Am ISSN： 0011-8532