Literature DB >> 28886365

Mitochondrial Replacement Techniques: Remaining Ethical Challenges.

Annelien L Bredenoord1, John B Appleby2.   

Abstract

Recent developments in the field of mitochondrial replacement technique (MRT) research and clinical practice have raised ethical concerns worldwide. We argue that the future use of MRTs requires a concerted effort among the global research and clinical community to implement and enforce responsible innovation and governance.
Copyright © 2017 Elsevier Inc. All rights reserved.

Mesh：

Year:  2017        PMID： 28886365     DOI： 10.1016/j.stem.2017.08.009

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  5 in total

Review 1.  After the fact-the case of CRISPR babies.

Authors:  Martin Sand; Annelien L Bredenoord; Karin R Jongsma
Journal:  Eur J Hum Genet       Date:  2019-06-24       Impact factor: 4.246

2.  Assisted reproductive technologies to prevent human mitochondrial disease transmission.

Authors:  Andy Greenfield; Peter Braude; Frances Flinter; Robin Lovell-Badge; Caroline Ogilvie; Anthony C F Perry
Journal:  Nat Biotechnol       Date:  2017-11-09       Impact factor: 54.908

3.  Reduction of mtDNA heteroplasmy in mitochondrial replacement therapy by inducing forced mitophagy.

Authors:  Xiao-Yan Fan; Lei Guo; Lei-Ning Chen; Shen Yin; Jiarong Wen; Sen Li; Jun-Yu Ma; Tao Jing; Man-Xi Jiang; Xiao-Hong Sun; Meilan Chen; Feng Wang; Zhen-Bo Wang; Chang-Fa Zhang; Xing-Hua Wang; Zhao-Jia Ge; Chun Hu; Lizhang Zeng; Wei Shen; Qing-Yuan Sun; Xiang-Hong Ou; Shi-Ming Luo
Journal:  Nat Biomed Eng       Date:  2022-04-18       Impact factor: 29.234

4.  Scientific and Ethical Issues in Mitochondrial Donation.

Authors:  Lyndsey Craven; Julie Murphy; Doug M Turnbull; Robert W Taylor; Grainne S Gorman; Robert McFarland
Journal:  New Bioeth       Date:  2018-04

5.  Public attitudes towards novel reproductive technologies: a citizens' jury on mitochondrial donation.

Authors:  A J Newson; S de Lacey; D K Dowling; S Murray; C M Sue; D R Thorburn; L Gillam; C Degeling
Journal:  Hum Reprod       Date:  2019-04-01       Impact factor: 6.918
  5 in total

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