Literature DB >> 28885607

Same-site surgical revision of failed trabeculectomy blebs with mitomycin C augmentation: long-term follow-up.

E Nikita1, I Murdoch1,2.   

Abstract

PurposeTo determine the long-term outcomes of same-site revision of failed filtering blebs with mitomycin C application.Patients and methodsNoncomparative retrospective case series of 45 eyes of 39 patients. Main outcome measures were surgical success (≤21, ≤18, and ≤16 mm Hg reduction in intraocular pressure (IOP)). Other outcome measures included best-corrected visual acuity (VA), visual field loss, number of glaucoma medications, need for further interventions, time from surgery to recommencement of medications or interventions, and complications.ResultsMean follow-up was 126±59.6 months (range 16-227 months). The overall success proportion at last follow-up was 96% for IOP ≤21 mm Hg (criterion 1), 91% for IOP ≤18 mm Hg (criterion 2), and 84% for IOP ≤16 mm Hg (criterion 3). Absolute success at last follow-up was 64%, 38%, and 33% for criteria 1, 2, and 3, respectively. Mean baseline IOP was reduced from 24.2±5.5 to 12.4±5.5 mm Hg at last follow-up. Ten eyes (22%) had early and 3 (7%) eyes had late complications. None of these complications resulted in visual loss or surgery failure. Nine eyes (20%) required further glaucoma surgery. Nine eyes (20%) required further glaucoma laser.ConclusionsSame-site, augmented, bleb revision is a safe and effective technique to control IOP and prevent further visual loss in patients with failed trabeculectomies.

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Year:  2017        PMID: 28885607      PMCID: PMC5811689          DOI: 10.1038/eye.2017.144

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  20 in total

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Authors:  Heloisa A Maestrini; Sebastião Cronemberger; Hérika Danielle S Matoso; José Roberto C Reis; Rafael V Mérula; Alberto Diniz Filho; Alberto Filho Diniz; Emília Sakurai; Graziele A Ferreira
Journal:  Ophthalmology       Date:  2010-11-05       Impact factor: 12.079

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Journal:  Surv Ophthalmol       Date:  1987 Nov-Dec       Impact factor: 6.048

6.  Trabeculectomy in the 21st century: a multicenter analysis.

Authors:  James F Kirwan; Alastair J Lockwood; Peter Shah; Alex Macleod; David C Broadway; Anthony J King; Andrew I McNaught; Pavi Agrawal
Journal:  Ophthalmology       Date:  2013-09-23       Impact factor: 12.079

7.  Long-term outcomes of repeat vs initial trabeculectomy in open-angle glaucoma.

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Journal:  Am J Ophthalmol       Date:  2009-11       Impact factor: 5.258

8.  The Advanced Glaucoma Intervention Study (AGIS): 13. Comparison of treatment outcomes within race: 10-year results.

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Journal:  Ophthalmology       Date:  2004-04       Impact factor: 12.079

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Authors:  Nitin Anand; Aldrin Khan
Journal:  J Glaucoma       Date:  2009-09       Impact factor: 2.503

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Authors:  Peng Tee Khaw; Mark Chiang; Peter Shah; Freda Sii; Alastair Lockwood; Ashkan Khalili
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  2 in total

1.  Efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation.

Authors:  Ewa Wałek; Joanna Przeździecka-Dołyk; Iwona Helemejko; Marta Misiuk-Hojło
Journal:  Int Ophthalmol       Date:  2019-10-01       Impact factor: 2.031

2.  Complications and post-operative interventions in XEN45 gel stent implantation in the treatment of open angle glaucoma-a systematic review and meta-analysis.

Authors:  Bjorn Kaijun Betzler; Sheng Yang Lim; Boon Ang Lim; Vivien Cherng Hui Yip; Bryan Chin Hou Ang
Journal:  Eye (Lond)       Date:  2022-03-28       Impact factor: 3.775

  2 in total

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