Breno A Rocha1, Lucianne M C Lima2, Lívia M R Paranaíba3,4, Angel da S Martinez2, Maria Betânia de O Pires1,3, Edimilson M de Freitas1,4, Camilla V Vilas Boas1, Mário R de Melo Filho1,3. 1. Oncologic Dentistry Service, Santa Casa Hospital, Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil. 2. Radiotherapy Service, Santa Casa of Montes Claros, Praça Honorato Alves, 22 - Centro, Montes Claros, Minas Gerais 39400-103, Brazil. 3. Dental School, University of Montes Claros, Av Rui Braga - Vila Mauricéia - Campus Darcy Ribeiro, Montes Claros, Minas Gerais 39401-089, Brazil. 4. Health Science Program, State University of Montes Claros, Montes Claros, Av. Cula Mangabeira, 562, Montes Claros, Minas Gerais 39401-001, Brazil.
Abstract
AIM: To fabricate and evaluate the efficacy of individualized intraoral stents to minimize the potential side effects of radiation on oral tissues in patients with early stages of lip cancer. BACKGROUND: Lower lip cancer is a common tumor found almost exclusively in middle-aged and elderly males. Surgery is the most common treatment of choice, although for less extensive lesions, exclusive radiotherapy may be preferred. Some studies have found that the use of intraoral stents in patients with intraoral cancer (e.g., of the tongue or floor of the mouth) obtained favorable results in preventing unnecessary radiation doses to adjacent normal tissue and reducing oral complications. However, studies investigating the efficacy of individualized intraoral stents in patients with lip cancer have not been reported in the literature. MATERIALS AND METHODS: Six patients with early stage lip cancer were eligible for curative radiotherapy and personalized intraoral stents. The stents were fabricated and all participants were evaluated for the occurrence of oral complications. RESULTS: The regions of the oral mucosa protected from radiation by intraoral stents showed no mucositis. One patient complained of mild oral dryness but without interference in habits. At follow-up, none of the patients had late xerostomia or signs of dental caries by radiation. CONCLUSIONS: The use of individualized intraoral stents was shown to be promising in reducing the adverse effects of radiation therapy in lip cancer patients. These findings highlight the importance of a multidisciplinary team during oncological therapy.
AIM: To fabricate and evaluate the efficacy of individualized intraoral stents to minimize the potential side effects of radiation on oral tissues in patients with early stages of lip cancer. BACKGROUND: Lower lip cancer is a common tumor found almost exclusively in middle-aged and elderly males. Surgery is the most common treatment of choice, although for less extensive lesions, exclusive radiotherapy may be preferred. Some studies have found that the use of intraoral stents in patients with intraoral cancer (e.g., of the tongue or floor of the mouth) obtained favorable results in preventing unnecessary radiation doses to adjacent normal tissue and reducing oral complications. However, studies investigating the efficacy of individualized intraoral stents in patients with lip cancer have not been reported in the literature. MATERIALS AND METHODS: Six patients with early stage lip cancer were eligible for curative radiotherapy and personalized intraoral stents. The stents were fabricated and all participants were evaluated for the occurrence of oral complications. RESULTS: The regions of the oral mucosa protected from radiation by intraoral stents showed no mucositis. One patient complained of mild oral dryness but without interference in habits. At follow-up, none of the patients had late xerostomia or signs of dental caries by radiation. CONCLUSIONS: The use of individualized intraoral stents was shown to be promising in reducing the adverse effects of radiation therapy in lip cancerpatients. These findings highlight the importance of a multidisciplinary team during oncological therapy.
Entities:
Keywords:
Head and neck cancer; Lip cancer; Radiotherapy; Side effects; Stents
Authors: Ashima Goel; Arvind Tripathi; Pooran Chand; Saumyendra V Singh; M C Pant; Amit Nagar Journal: Int J Prosthodont Date: 2010 Sep-Oct Impact factor: 1.681
Authors: Rajesh V Lalla; Joanne Bowen; Andrei Barasch; Linda Elting; Joel Epstein; Dorothy M Keefe; Deborah B McGuire; Cesar Migliorati; Ourania Nicolatou-Galitis; Douglas E Peterson; Judith E Raber-Durlacher; Stephen T Sonis; Sharon Elad Journal: Cancer Date: 2014-02-25 Impact factor: 6.860
Authors: Tanaya S Deshpande; Pierre Blanchard; Li Wang; Robert L Foote; Xiaodong Zhang; Steven J Frank Journal: Curr Treat Options Oncol Date: 2018-11-09
Authors: Stephen Palasi; Ning Zhang; Mikaela Bankston; Joy Godby; Hannah Burrows; Jennifer Lagunas; William Perkison; Brandon Gunn; Mark S Chambers; David I Rosenthal; William Morrison; Adam Garden; Clifton David Fuller; Sharon Giordano; Eugene J Koay Journal: Clin Transl Radiat Oncol Date: 2021-08-08