Literature DB >> 28878852

Potential Adjunctive Role of Radiosynovectomy in Primary Synovial Osteochondromatosis of the Knee: A Case Report.

Shelvin Kumar Vadi1, Devendra Kumar Chouhan2, Arun Kumar Reddy Gorla1, Jaya Shukla1, Ashwani Sood1, Bhagwant Rai Mittal1.   

Abstract

Primary synovial osteochondromatosis (PSOC) is a rare but clinically significant cause of morbidity especially in the male population. Surgery is the primary treatment of choice, but the recurrence rate is reported to be high. Moreover, the presence of widespread loose bodies makes it a cumbersome procedure. The complete removal of the disease is tough at times and results in early recurrence. Radiosynovectomy is an established technique for treating various joint arthropathies. The role of radiosynovectomy in case of PSOC has not yet been explored. This case report described the case of a young male with PSOC of the knee joint who was treated with radiosynovectomy for pain relief. The patient reported complete relief from the pain along with significant improvement in joint mobility. The post-therapy three-phase bone scan also validated the reduction in joint inflammation. The patient was taken for surgical removal of the redundant loose bodies after a significant improvement in the pain and reduction in inflammation. Post-therapy radiation fibrosis of the synovium also helped in the en bloc removal of the disease. The role of radiosynovectomy in PSOC needs to be further explored concerning its potential role as an adjuvant to surgical procedures.

Entities:  

Keywords:  Primary synovial osteochondromatosis (PSOC); Radiation synovectomy; Radiosynoviorthesis; Rhenium-188 (188Re)

Year:  2016        PMID: 28878852      PMCID: PMC5567622          DOI: 10.1007/s13139-016-0466-1

Source DB:  PubMed          Journal:  Nucl Med Mol Imaging        ISSN: 1869-3474


  7 in total

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Journal:  Cancer Genet Cytogenet       Date:  2003-01-01

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Authors:  T Shpitzer; A Ganel; S Engelberg
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3.  Synovial osteochondromatosis: a histopathological study of thirty cases.

Authors:  J W Milgram
Journal:  J Bone Joint Surg Am       Date:  1977-09       Impact factor: 5.284

4.  Role of rhenium-188 tin colloid radiosynovectomy in patients with inflammatory knee joint conditions refractory to conventional therapy.

Authors:  Shamim Ahmed Shamim; Rakesh Kumar; Dhanapathi Halanaik; Ashok Kumar; Varun Shandal; Jaya Shukla; Ajay Kumar; Vivek Trikha; Prem Chandra; Gurupad Bandopadhayaya; Arun Malhotra
Journal:  Nucl Med Commun       Date:  2010-09       Impact factor: 1.690

5.  Primary synovial chondromatosis and synovial chondrosarcoma: a pictorial review.

Authors:  B Wittkop; A M Davies; D C Mangham
Journal:  Eur Radiol       Date:  2002-03-19       Impact factor: 5.315

6.  Familial synovial chondromatosis combined with dwarfism.

Authors:  J Felbel; U Gresser; G Lohmöller; N Zöllner
Journal:  Hum Genet       Date:  1992-01       Impact factor: 4.132

7.  [Multicenter study of radiosynoviorthesis. Clinical outcome in osteoarthritis and other disorders with concomitant synovitis in comparison with rheumatoid arthritis].

Authors:  H Rau; K Lohmann; C Franke; G Goretzki; M A Lemb; J Müller; P J Panholzer; E Stelling; J Spitz
Journal:  Nuklearmedizin       Date:  2004-03       Impact factor: 1.379

  7 in total
  1 in total

1.  A Recurrent Synovial Osteochondromatosis of the Knee: A Case Report.

Authors:  Sripur Manandhar; Jiazhen Li; Xin-Chang Lu; Yan Zhang; Yi Zhang; Yongkui Liu; Chao Zhang
Journal:  Int Med Case Rep J       Date:  2021-02-10
  1 in total

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