Literature DB >> 28878545

Atraumatic segmental atypical femur fracture secondary to bisphosphonate use: A case report.

Andrew J Lovy1, Diana Patterson1, Laura Skeeles2, Richard Ghillani1,2, David Joseph1,2, Yangguan Wu2, Rohit Hasija2.   

Abstract

Atypical femur fractures as a result of long term bisphosphonate use are characterized by several unique radiographic features. We describe an atypical femur fracture treated by cephalomedullary nail with a previously undescribed segmental fracture pattern. Other than 1.5 years of bisphosphonate use the patient did not have any other risk factors known to cause atypical femur fractures. Judicious bisphosphonate use as well as increased awareness of the associated complications may help reduce the rate of bisphosphonate associated atypical femur fractures.

Entities:  

Keywords:  Atypical Femur Fracture; Bisphosphonate; Insufficiency fracture

Year:  2017        PMID： 28878545      PMCID： PMC5574839          DOI： 10.1016/j.jcot.2017.03.005

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN： 0976-5662


  23 in total

Review 1.  Bisphosphonate-associated fractures of the femur: pathophysiology and treatment.

Authors:  Thomas A Einhorn; Yelena Bogdan; Paul Tornetta
Journal:  J Orthop Trauma       Date:  2014-07       Impact factor: 2.512

2.  Post-operative outcomes of atypical femoral subtrochanteric fracture in patients on bisphosphonate therapy.

Authors:  B J X Teo; J S B Koh; S K Goh; M A Png; D T C Chua; T S Howe
Journal:  Bone Joint J       Date:  2014-05       Impact factor: 5.082

3.  Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib.

Authors:  T Mashiba; T Hirano; C H Turner; M R Forwood; C C Johnston; D B Burr
Journal:  J Bone Miner Res       Date:  2000-04       Impact factor: 6.741

4.  Antegrade or retrograde reamed femoral nailing. A prospective, randomised trial.

Authors:  P Tornetta; D Tiburzi
Journal:  J Bone Joint Surg Br       Date:  2000-07

5.  Teriparatide, vitamin D, and calcium healed bilateral subtrochanteric stress fractures in a postmenopausal woman with a 13-year history of continuous alendronate therapy.

Authors:  Stephen J Gomberg; Rosanna L Wustrack; Nicola Napoli; Claude D Arnaud; Dennis M Black
Journal:  J Clin Endocrinol Metab       Date:  2011-03-23       Impact factor: 5.958

6.  Teriparatide for acceleration of fracture repair in humans: a prospective, randomized, double-blind study of 102 postmenopausal women with distal radial fractures.

Authors:  Per Aspenberg; Harry K Genant; Torsten Johansson; Antonio J Nino; Kyoungah See; Kelly Krohn; Pedro A García-Hernández; Christopher P Recknor; Thomas A Einhorn; Gail P Dalsky; Bruce H Mitlak; Anke Fierlinger; Mark C Lakshmanan
Journal:  J Bone Miner Res       Date:  2010-02       Impact factor: 6.741

7.  Changes in vertebral strength-density and energy absorption-density relationships following bisphosphonate treatment in beagle dogs.

Authors:  M R Allen; D B Burr
Journal:  Osteoporos Int       Date:  2007-08-21       Impact factor: 4.507

Review 8.  Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research.

Authors:  Elizabeth Shane; David Burr; Bo Abrahamsen; Robert A Adler; Thomas D Brown; Angela M Cheung; Felicia Cosman; Jeffrey R Curtis; Richard Dell; David W Dempster; Peter R Ebeling; Thomas A Einhorn; Harry K Genant; Piet Geusens; Klaus Klaushofer; Joseph M Lane; Fergus McKiernan; Ross McKinney; Alvin Ng; Jeri Nieves; Regis O'Keefe; Socrates Papapoulos; Tet Sen Howe; Marjolein C H van der Meulen; Robert S Weinstein; Michael P Whyte
Journal:  J Bone Miner Res       Date:  2013-10-01       Impact factor: 6.741

9.  Bone turnover in bone biopsies of patients with low-energy cortical fractures receiving bisphosphonates: a case series.

Authors:  Reina Armamento-Villareal; Nicola Napoli; Kathryn Diemer; Marcus Watkins; Roberto Civitelli; Steven Teitelbaum; Deborah Novack
Journal:  Calcif Tissue Int       Date:  2009-06-23       Impact factor: 4.333

10.  Bisphosphonate-associated atypical fracture of the femur: Spontaneous healing with drug holiday and re-appearance after resumed drug therapy with bilateral simultaneous displaced fractures--a case report.

Authors:  Ken Lee Puah; Mann Hong Tan
Journal:  Acta Orthop       Date:  2011-05-11       Impact factor: 3.717
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