Hannan M Braun1,2, Jury Candelario3, Courtney L Hanlon4, Eddy R Segura2,5, Jesse L Clark2, Judith S Currier2, Jordan E Lake2,6. 1. 1 School of Medicine, University of California , San Francisco, San Francisco, California. 2. 2 South American Program in HIV Prevention Research, Division of Infectious Diseases, Department of Medicine, David Geffen School of Medicine , Los Angeles, California. 3. 3 APAIT, Special Service for Groups , Los Angeles, California. 4. 4 Geisel School of Medicine, Dartmouth College , Hanover, New Hampshire. 5. 5 Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas , Lima, Peru . 6. 6 Division of Infectious Diseases, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston , Houston, Texas.
Abstract
PURPOSE: Both hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence. METHODS: This study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA. RESULTS: Fifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns. CONCLUSION: Imperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.
PURPOSE: Both hormone therapy (HT) and antiretroviral therapy (ART) can be lifesaving for transgender women (TW) living with HIV, but each has side effects and potential drug-drug interactions (DDI). We assessed how concerns about HT-ART interactions affect treatment adherence. METHODS: This study used a cross-sectional survey of TW (n = 87) in Los Angeles, CA. RESULTS: Fifty-four percent were living with HIV; 64% used HT. Only 49% of TW living with HIV discussed ART-HT DDI with their provider; 40% reported not taking ART (12%), HT (12%), or both (16%) as directed due to DDI concerns. CONCLUSION: Imperfect HT/ART use and limited provider communication suggests a need for improved HT-ART integration.
Entities:
Keywords:
HIV; antiretroviral therapy; health disparities; medication adherence; transgender
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