Seiichiro Aoe1, Yasunori Ichinose2, Noriko Kohyama2, Kozo Komae3, Asuka Takahashi3, Daigo Abe3, Toji Yoshioka3, Takashi Yanagisawa2. 1. Department of Food Science, Otsuma Women's University, Tokyo, Japan. Electronic address: s-aoe@otsuma.ac.jp. 2. Institute of Crop Science, National Agriculture and Food Research Organization, Tsukuba, Japan. 3. Western Region Agricultural Research Center, National Agriculture and Food Research Organization, Zentsuji, Japan.
Abstract
OBJECTIVE: The aim of this study was to investigate whether a diet in which high β-glucan barley was substituted for rice would reduce visceral fat obesity in Japanese individuals. METHODS: A randomized, double-blind, placebo-controlled intervention study was conducted with 100 Japanese individuals with waist circumference (WC) ≥85 cm for men or ≥90 cm for women and body mass index (BMI) ≥24 kg/m2. Participants were randomly assigned to consume a mixture of rice and either high β-glucan barley (test group, 4.4 g/d) or β-glucan-free barley (placebo group) for 12 wk. Blood samples and computed tomography scans were obtained before and after the trial. RESULTS: Both groups showed decreases in body weight and BMI, and these changes were significantly greater in the test group. WC and visceral fat area (VFA) significantly decreased in both groups (VFA: -10.7 cm2 in the test group; -6.8 cm2 in the placebo group). These changes did not differ significantly between the groups. However, a subgroup analysis of participants with VFA ≥100 cm2 showed a significant decrease in the test group, and this decrease was significantly greater than in the placebo group. CONCLUSIONS: The intake of high β-glucan barley led to significant and safe reductions in VFA, body weight, BMI, and WC in individuals with visceral fat obesity with VFA ≥100 cm2. Barley high in β-glucan may contribute to preventing visceral fat obesity.
RCT Entities:
OBJECTIVE: The aim of this study was to investigate whether a diet in which high β-glucan barley was substituted for rice would reduce visceral fat obesity in Japanese individuals. METHODS: A randomized, double-blind, placebo-controlled intervention study was conducted with 100 Japanese individuals with waist circumference (WC) ≥85 cm for men or ≥90 cm for women and body mass index (BMI) ≥24 kg/m2. Participants were randomly assigned to consume a mixture of rice and either high β-glucan barley (test group, 4.4 g/d) or β-glucan-free barley (placebo group) for 12 wk. Blood samples and computed tomography scans were obtained before and after the trial. RESULTS: Both groups showed decreases in body weight and BMI, and these changes were significantly greater in the test group. WC and visceral fat area (VFA) significantly decreased in both groups (VFA: -10.7 cm2 in the test group; -6.8 cm2 in the placebo group). These changes did not differ significantly between the groups. However, a subgroup analysis of participants with VFA ≥100 cm2 showed a significant decrease in the test group, and this decrease was significantly greater than in the placebo group. CONCLUSIONS: The intake of high β-glucan barley led to significant and safe reductions in VFA, body weight, BMI, and WC in individuals with visceral fat obesity with VFA ≥100 cm2. Barley high in β-glucan may contribute to preventing visceral fat obesity.
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