G C Rodríguez-Roca1, A Segura-Fragoso2, A Villarín-Castro3, F J Alonso-Moreno4, L Rodríguez-Padial5, M L Rodríguez-García6, J A Fernández-Conde7, G A Rojas-Martelo8, A Menchén-Herreros9, C Escobar-Cervantes10, J Fernández-Martín11, L M Artigao-Rodenas12, J A Carbayo-Herencia13, J Hernández-Moreno14. 1. Investigador Principal y Director del Proyecto RICARTO, Centro de Salud de La Puebla de Montalbán, La Puebla de Montalbán, Toledo, España. Electronic address: grodriguezr@semergen.es. 2. Instituto de Ciencias de la Salud de Castilla-La Mancha, Consejería de Sanidad, Talavera de la Reina, Toledo, España. 3. Unidad Docente Multiprofesional de Atención Familiar y Comunitaria, Gerencia de Atención Primaria de Toledo, Toledo, España. 4. Centro de Salud Sillería, Toledo, España. 5. Servicio de Cardiología, Complejo Hospitalario Universitario de Toledo, Toledo, España. 6. Enfermera del Estudio RICARTO, Gerencia de Atención Primaria de Toledo, Toledo, España. 7. Unidad Administrativa, Gerencia de Atención Primaria de Toledo, Toledo, España. 8. Médico Interno Residente de Medicina Familiar y Comunitaria, Hospital Ramón y Cajal, Madrid, España. 9. Laboratorio de Análisis Clínicos, Hospital Virgen de la Salud, Complejo Hospitalario Universitario de Toledo, Toledo, España. 10. Servicio de Cardiología, Hospital Universitario La Paz, Madrid, España. 11. Servicio de Investigación e Innovación, Consejería de Sanidad, Junta de Comunidades de Castilla-La Mancha, Toledo, España. 12. Centro de Salud Zona III, Grupo de Enfermedades Vasculares de Albacete (GEVA), Albacete, España. 13. Grupo de Enfermedades Vasculares de Albacete (GEVA), Unidad de Lípidos, Hospital Quirónsalud de Albacete; Profesor de las Universidades Miguel Hernández de Alicante y Católica de San Antonio de Murcia, y del Centro Universitario de la Defensa de San Javier de Murcia, Albacete, España. 14. Centro de Salud de Polán, Polán, Toledo, España.
Abstract
INTRODUCTION: The aim of this study was to assess cardiovascular risk (CVR) by investigating the prevalence of CVR factors (CVRF), target organ damage (TOD), and cardiovascular disease (CVD) in general population of the health area of Toledo, Spain. MATERIAL AND METHODS: Epidemiological and observational study that analysed a sample from the general population aged 18years or older, randomly selected from a database of health cards stratified by age and gender. Clinical history, physical examination, and complementary tests were performed. Total blood and serum samples were frozen at -85°C to evaluate genetic studies in the future. Standard statistical analysis was performed. CVR was assessed by the SCORE scale calibrated for the Spanish population, and the Framingham Heart Study scale. RESULTS: A total of 1,500 individuals (mean age 49.1±15.8years, 55.6% women) were included. Prevalences: dyslipidaemia 56.9% (95% confidence interval [95% CI]: 54.3-59.4), hypertension 33.0% (95%CI: 30.6-35.4), diabetes mellitus 8.6% (95%CI: 7.17-10.1), smoking 24.2% (95%CI; 122.0-26.4), obesity 25.3% (95%CI; 23.1-27.5), and sedentary life-style 39.4% (95%CI; 36.9-41.8). No CVRF was reported in 21.1% of cases, and 18.6% had 3-5 CVRF. TOD: electrocardiographic left ventricular hypertrophy, 4.3%, peripheral artery disease, 10.1% (Doppler ultrasound), and 15.3% (oscillometric device), microalbuminuria, 4.3%, sub-clinical renal disease, 3.2%, and nephropathy in 3.8% (CKD-EPI). At least one CVD was reported in 9.2% of cases. A low CVR (SCORE) was present in 44.6% of individuals. CONCLUSIONS: Dyslipidaemia was found in 60% of individuals, 40% had a sedentary life-style, 30% with hypertension, 20% smoked, 20% obesity, and almost 10% with diabetes. More than a half of individuals have a moderate-high-very high risk. The prevalence of TOD and CVD are significant.
INTRODUCTION: The aim of this study was to assess cardiovascular risk (CVR) by investigating the prevalence of CVR factors (CVRF), target organ damage (TOD), and cardiovascular disease (CVD) in general population of the health area of Toledo, Spain. MATERIAL AND METHODS: Epidemiological and observational study that analysed a sample from the general population aged 18years or older, randomly selected from a database of health cards stratified by age and gender. Clinical history, physical examination, and complementary tests were performed. Total blood and serum samples were frozen at -85°C to evaluate genetic studies in the future. Standard statistical analysis was performed. CVR was assessed by the SCORE scale calibrated for the Spanish population, and the Framingham Heart Study scale. RESULTS: A total of 1,500 individuals (mean age 49.1±15.8years, 55.6% women) were included. Prevalences: dyslipidaemia 56.9% (95% confidence interval [95% CI]: 54.3-59.4), hypertension 33.0% (95%CI: 30.6-35.4), diabetes mellitus 8.6% (95%CI: 7.17-10.1), smoking 24.2% (95%CI; 122.0-26.4), obesity 25.3% (95%CI; 23.1-27.5), and sedentary life-style 39.4% (95%CI; 36.9-41.8). No CVRF was reported in 21.1% of cases, and 18.6% had 3-5 CVRF. TOD: electrocardiographic left ventricular hypertrophy, 4.3%, peripheral artery disease, 10.1% (Doppler ultrasound), and 15.3% (oscillometric device), microalbuminuria, 4.3%, sub-clinical renal disease, 3.2%, and nephropathy in 3.8% (CKD-EPI). At least one CVD was reported in 9.2% of cases. A low CVR (SCORE) was present in 44.6% of individuals. CONCLUSIONS: Dyslipidaemia was found in 60% of individuals, 40% had a sedentary life-style, 30% with hypertension, 20% smoked, 20% obesity, and almost 10% with diabetes. More than a half of individuals have a moderate-high-very high risk. The prevalence of TOD and CVD are significant.
Keywords:
Cardiovascular disease; Cardiovascular risk; Cardiovascular risk factors; Daño orgánico subclínico; Enfermedad cardiovascular; Factores de riesgo cardiovascular; Población general aleatorizada; Random general population; Riesgo cardiovascular; Sub-clinical organ damage; Toledo health area; Área sanitaria de Toledo
Authors: Alejandro Villarín Castro; Antonio Segura Fragoso; Francisco Javier Alonso Moreno; Marta Sánchez Pérez; Luis Rodríguez Padial; Gustavo Cristóbal Rodríguez Roca Journal: High Blood Press Cardiovasc Prev Date: 2019-08-26