Julia O Totosy de Zepetnek1, Masae Miyatani2, Maggie Szeto2, Lora M Giangregorio2,3, B Catharine Craven2,4. 1. a Faculty of Kinesiology and Health Studies, University of Regina , 3737 Wascana Parkway, Regina , SK , S4S 0A2. 2. b Toronto Rehabilitation Institute, Spinal Cord Rehabilitation Program , University Health Network, 520 Sutherland Drive , Toronto , ON , M4G 3V9. 3. c Department of Kinesiology , University of Waterloo, 200 University Ave , Waterloo , ON , N2L 3G1. 4. d Department of Medicine , University of Toronto, 1 King's College Cir , Toronto , ON , M5S 1A3.
Abstract
OBJECTIVE: A pilot study to evaluate the therapeutic potential of 40 weeks of passive standing with whole body vibration (PS-WBV) on central and peripheral arterial stiffness among men with chronic spinal cord injury (SCI). METHODS: Consenting participants were pre-screened to ensure safe participation. Fifteen individuals with chronic SCI were enrolled to participate in PS-WBV sessions three times per week for 40 weeks on a modified WAVE platform custom-fitted with an EASYStand 5000. Knee angle was set at 160°, and vibration parameters were 45Hz frequency and 0.7mm displacement. Each 45-minute session of PS-WBV training was intermittent (60 seconds on and 120 seconds off). Aortic and leg pulse wave velocity (PWV) was measured at baseline, mid-point (20 weeks) and exit (40 weeks). RESULTS: Nine males (age 41±11 years, American Spinal Injury Association Impairment Scale A-D, neurological level of injury T4-T10, years post-injury 12±8 years) completed the intervention. Aortic PWV was collected on n=7 at exit, and leg PWV was collected on n=6 at exit. No changes over time were found for either aortic PWV (P = 0.46) or leg PWV (P = 0.54). One possible study-related serious adverse event occurred during study intervention: the development of a grade III pressure sore on the right proximal anterior shin (n=1). CONCLUSION: Forty weeks of PS-WBV in adults with SCI did not result in an observable change in arterial stiffness.
OBJECTIVE: A pilot study to evaluate the therapeutic potential of 40 weeks of passive standing with whole body vibration (PS-WBV) on central and peripheral arterial stiffness among men with chronic spinal cord injury (SCI). METHODS: Consenting participants were pre-screened to ensure safe participation. Fifteen individuals with chronic SCI were enrolled to participate in PS-WBV sessions three times per week for 40 weeks on a modified WAVE platform custom-fitted with an EASYStand 5000. Knee angle was set at 160°, and vibration parameters were 45Hz frequency and 0.7mm displacement. Each 45-minute session of PS-WBV training was intermittent (60 seconds on and 120 seconds off). Aortic and leg pulse wave velocity (PWV) was measured at baseline, mid-point (20 weeks) and exit (40 weeks). RESULTS: Nine males (age 41±11 years, American Spinal Injury Association Impairment Scale A-D, neurological level of injury T4-T10, years post-injury 12±8 years) completed the intervention. Aortic PWV was collected on n=7 at exit, and leg PWV was collected on n=6 at exit. No changes over time were found for either aortic PWV (P = 0.46) or leg PWV (P = 0.54). One possible study-related serious adverse event occurred during study intervention: the development of a grade III pressure sore on the right proximal anterior shin (n=1). CONCLUSION: Forty weeks of PS-WBV in adults with SCI did not result in an observable change in arterial stiffness.
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Authors: Yoav Ben-Shlomo; Melissa Spears; Chris Boustred; Margaret May; Simon G Anderson; Emelia J Benjamin; Pierre Boutouyrie; James Cameron; Chen-Huan Chen; J Kennedy Cruickshank; Shih-Jen Hwang; Edward G Lakatta; Stephane Laurent; João Maldonado; Gary F Mitchell; Samer S Najjar; Anne B Newman; Mitsuru Ohishi; Bruno Pannier; Telmo Pereira; Ramachandran S Vasan; Tomoki Shokawa; Kim Sutton-Tyrell; Francis Verbeke; Kang-Ling Wang; David J Webb; Tine Willum Hansen; Sophia Zoungas; Carmel M McEniery; John R Cockcroft; Ian B Wilkinson Journal: J Am Coll Cardiol Date: 2013-11-13 Impact factor: 24.094