BACKGROUND: Arterial stiffness measurements, generally from pulse wave velocity (PWV), are widely used with little knowledge of their relationship to long-term cardiovascular mortality in general populations. METHODS AND RESULTS: We studied a cohort of 492 Japanese-Americans living in Hawaii (mean age: 63.7 +/-8.8 years) to assess the relationship between PWV and cardiovascular disease mortality and all-cause mortality. During the 10-year follow-up, 43 patients died (14 from cardiovascular events). The cohort was divided into 2 groups by the cut-off value of PWV (9.9 m/s) represented in the receiver operating characteristic curve. The risk ratio for PWV values >9.9 m/s to all-cause mortality was 1.28 [95% confidence interval (CI): 1.14-1.42], and adjusted for other risk factors this ratio was 1.42 (95% CI: 0.96-2.11). The corresponding risk ratios for cardiovascular mortality was 4.46 (95% CI: 1.61-12.32) and 4.24 (95% CI: 1.39-12.96), respectively. CONCLUSIONS: The present study demonstrated that an increased PWV value is associated with future cardiovascular disease death in Japanese-Americans living in Hawaii.
BACKGROUND: Arterial stiffness measurements, generally from pulse wave velocity (PWV), are widely used with little knowledge of their relationship to long-term cardiovascular mortality in general populations. METHODS AND RESULTS: We studied a cohort of 492 Japanese-Americans living in Hawaii (mean age: 63.7 +/-8.8 years) to assess the relationship between PWV and cardiovascular disease mortality and all-cause mortality. During the 10-year follow-up, 43 patients died (14 from cardiovascular events). The cohort was divided into 2 groups by the cut-off value of PWV (9.9 m/s) represented in the receiver operating characteristic curve. The risk ratio for PWV values >9.9 m/s to all-cause mortality was 1.28 [95% confidence interval (CI): 1.14-1.42], and adjusted for other risk factors this ratio was 1.42 (95% CI: 0.96-2.11). The corresponding risk ratios for cardiovascular mortality was 4.46 (95% CI: 1.61-12.32) and 4.24 (95% CI: 1.39-12.96), respectively. CONCLUSIONS: The present study demonstrated that an increased PWV value is associated with future cardiovascular disease death in Japanese-Americans living in Hawaii.
Authors: Aaron M Secrest; Sara L Marshall; Rachel G Miller; Catherine T Prince; Trevor J Orchard Journal: Diabetes Technol Ther Date: 2011-08-05 Impact factor: 6.118
Authors: Julia O Totosy de Zepetnek; Masae Miyatani; Maggie Szeto; Lora M Giangregorio; B Catharine Craven Journal: J Spinal Cord Med Date: 2017-09-04 Impact factor: 1.985
Authors: Raymond R Townsend; Neil J Wimmer; Julio A Chirinos; Afshin Parsa; Matthew Weir; Kalyani Perumal; James P Lash; Jing Chen; Susan P Steigerwalt; John Flack; Alan S Go; Mohammed Rafey; Mahboob Rahman; Angela Sheridan; Crystal A Gadegbeku; Nancy A Robinson; Marshall Joffe Journal: Am J Hypertens Date: 2009-12-17 Impact factor: 2.689