Kevin D Gillis1,2,3, Xin A Liu4, Andrea Marcantoni5, Valentina Carabelli5. 1. Department of Bioengineering, University of Missouri, Columbia, MO, USA. gillisk@missouri.edu. 2. Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO, USA. gillisk@missouri.edu. 3. Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, USA. gillisk@missouri.edu. 4. Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, USA. 5. Department of Drug Science and "NIS" Inter-departmental Centre, University of Torino, Torino, Italy.
Abstract
Carbon-fiber electrodes (CFEs) are the gold standard for quantifying the release of oxidizable neurotransmitters from single vesicles and single cells. Over the last 15 years, microfabricated devices have emerged as alternatives to CFEs that offer the possibility of higher throughput, subcellular spatial resolution of exocytosis, and integration with other techniques for probing exocytosis including microfluidic cell handling and solution exchange, optical imaging and stimulation, and electrophysiological recording and stimulation. Here we review progress in developing electrochemical electrode devices capable of resolving quantal exocytosis that are fabricated using photolithography.
pan class="Chemical">Carbon-fiber electrodes (CFEs) are the gold standard for quantifying the release of oxidizable neurotransmitters from single vesicles and single cells. Over the last 15 years, microfabricated devices have emerged as alternatives to CFEs that offer the possibility of higher throughput, subcellular span>tial resolution of exocytosis, and integration with other techniques for probing exocytosis including microfluidic cell handling and solution exchange, optical imaging and stimulation, and electrophysiological recording and stimulation. Here we review progress in developing electrochemical electrode devices capable of resolving quantal exocytosis that are fabricated using photolithography.
Authors: J M Finnegan; K Pihel; P S Cahill; L Huang; S E Zerby; A G Ewing; R T Kennedy; R M Wightman Journal: J Neurochem Date: 1996-05 Impact factor: 5.372
Authors: Ismail Hafez; Kassandra Kisler; Khajak Berberian; Gregor Dernick; Vicente Valero; Ming G Yong; Harold G Craighead; Manfred Lindau Journal: Proc Natl Acad Sci U S A Date: 2005-09-19 Impact factor: 11.205
Authors: Yuqing Lin; Raphaël Trouillon; Maria I Svensson; Jacqueline D Keighron; Ann-Sofie Cans; Andrew G Ewing Journal: Anal Chem Date: 2012-03-06 Impact factor: 6.986
Authors: Sang Yoon Yang; Brian N Kim; Alexander A Zakhidov; Priscilla G Taylor; Jin-Kyun Lee; Christopher K Ober; Manfred Lindau; George G Malliaras Journal: Adv Mater Date: 2011-03-14 Impact factor: 30.849
Authors: Carlos I Dorta-Quinones; Meng Huang; John C Ruelas; Joannalyn Delacruz; Alyssa B Apsel; Bradley A Minch; Manfred Lindau Journal: IEEE Trans Biomed Circuits Syst Date: 2018-05-15 Impact factor: 3.833