Literature DB >> 28865738

Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris.

G Moore1, S Schelenz2, A M Borman3, E M Johnson3, C S Brown4.   

Abstract

Candida auris appears to be transmitted readily between patients, yet information regarding the efficacy of environmental disinfection and skin decolonization is lacking. A quantitative suspension test (EN 13624:2013) was used to evaluate the yeasticidal activity of different chemical disinfectants and antiseptics against C. auris and Candida albicans. When tested in suspension, both a chlorine-based disinfectant and iodine-based skin antiseptic were effective against C. auris, suggesting that their use could reduce environmental contamination and skin colonization, respectively, if applied appropriately. Chlorhexidine-based products may also be effective. However, in this study, activity depended on formulation, specifically the presence of isopropyl alcohol. Crown
Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Candida auris; Chlorhexidine gluconate; Chlorine; Povidone-iodine; Quantitative suspension test

Mesh:

Substances:

Year:  2017        PMID: 28865738     DOI: 10.1016/j.jhin.2017.08.019

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  18 in total

Review 1.  Candida auris: a Review of the Literature.

Authors:  Anna Jeffery-Smith; Surabhi K Taori; Silke Schelenz; Katie Jeffery; Elizabeth M Johnson; Andrew Borman; Rohini Manuel; Colin S Brown
Journal:  Clin Microbiol Rev       Date:  2017-11-15       Impact factor: 26.132

2.  Inactivation of the multi-drug resistant pathogen Candida auris using ultraviolet germicidal irradiation (UVGI).

Authors:  Angela R Lemons; Tia L McClelland; Stephen B Martin; William G Lindsley; Brett J Green
Journal:  J Hosp Infect       Date:  2020-04-10       Impact factor: 3.926

Review 3.  Candida auris: an Emerging Fungal Pathogen.

Authors:  Emily S Spivak; Kimberly E Hanson
Journal:  J Clin Microbiol       Date:  2018-01-24       Impact factor: 5.948

Review 4.  Candida auris: Disinfectants and Implications for Infection Control.

Authors:  Tsun S N Ku; Carla J Walraven; Samuel A Lee
Journal:  Front Microbiol       Date:  2018-04-12       Impact factor: 5.640

Review 5.  Healthcare-associated fungal outbreaks: New and uncommon species, New molecular tools for investigation and prevention.

Authors:  Marie-Elisabeth Bougnoux; Sophie Brun; Jean-Ralph Zahar
Journal:  Antimicrob Resist Infect Control       Date:  2018-03-27       Impact factor: 4.887

6.  The environmental stress sensitivities of pathogenic Candida species, including Candida auris, and implications for their spread in the hospital setting.

Authors:  Helen Heaney; Juliette Laing; Linda Paterson; Alan W Walker; Neil A R Gow; Elizabeth M Johnson; Donna M MacCallum; Alistair J P Brown
Journal:  Med Mycol       Date:  2020-08-01       Impact factor: 4.076

Review 7.  Combined Antifungal Resistance and Biofilm Tolerance: the Global Threat of Candida auris.

Authors:  Ryan Kean; Gordon Ramage
Journal:  mSphere       Date:  2019-07-31       Impact factor: 4.389

8.  Efficacy of Delayed Therapy with Fosmanogepix (APX001) in a Murine Model of Candida auris Invasive Candidiasis.

Authors:  Nathan P Wiederhold; Laura K Najvar; Karen J Shaw; Rosie Jaramillo; Hoja Patterson; Marcos Olivo; Gabriel Catano; Thomas F Patterson
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

Review 9.  Assessing the Potential for Unintended Microbial Consequences of Routine Chlorhexidine Bathing for Prevention of Healthcare-associated Infections.

Authors:  Ahmed Babiker; Joseph D Lutgring; Scott Fridkin; Mary K Hayden
Journal:  Clin Infect Dis       Date:  2021-03-01       Impact factor: 9.079

Review 10.  Biocidal Resistance in Clinically Relevant Microbial Species: A Major Public Health Risk.

Authors:  Elaine Meade; Mark Anthony Slattery; Mary Garvey
Journal:  Pathogens       Date:  2021-05-14
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