Literature DB >> 28856149

Is idiopathic granulomatous mastitis a surgical disease? The jury is still out.

Demetrios Moris1, Christos Damaskos1, Spyridon Davakis1, Michail Vailas1, Nikolaos Garmpis1, Eleftherios Spartalis1, Michael Kontos1, Konstantinos Kontzoglou1.   

Abstract

Idiopathic granulomatous mastitis (IGM), is a rare entity of chronic inflammatory disorder of the breast of unknown etiology. Very few cases have been described so far, almost exclusively in women. Here we describe a case of IGM in a 53-year-old man presented with a right breast mass, progressively enlarging during the last 6 months. Due to the findings of clinical examination and CT-scan, the suspicion for a potentially malignant lesion was given and the decision for surgical resection was made. Microscopic analysis of the specimen showed non-caseating granulomas around mammary lobules, findings compatible with IGM. The patient is recurrence-free at 18-month follow-up. IGM is a rare benign inflammatory breast disease, usually seen in females of reproductive age. Establishing a diagnosis can be challenging for a surgeon and requires a high index of suspicion as most patients are initially misdiagnosed by their primary care physicians. Steroids and immunosuppressive drugs are considered as fundamental treatment modalities but they are correlated with increased rates of disease response and recurrence. On the contrary, surgical resection demonstrated significantly superior results compared to steroid-alone treatment in terms of recurrence and post-treatment recovery.

Entities:  

Keywords:  Idiopathic; breast; granulomatous; lesion; mastitis; surgery; treatment

Year:  2017        PMID: 28856149      PMCID: PMC5555981          DOI: 10.21037/atm.2017.05.24

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  16 in total

Review 1.  Methotrexate in the management of idiopathic granulomatous mastitis: review of 108 published cases and report of four cases.

Authors:  Sami Akbulut; Davut Yilmaz; Sule Bakir
Journal:  Breast J       Date:  2011-09-21       Impact factor: 2.431

2.  Idiopathic granulomatous mastitis in the male breast.

Authors:  K Marcus Reddy; Carl E R Meyer; Amir Nakdjevani; Sunita Shrotria
Journal:  Breast J       Date:  2005 Jan-Feb       Impact factor: 2.431

3.  Idiopathic granulomatous mastitis: diagnostic and therapeutic challenges to general surgeon.

Authors:  Santosh C Gudimani; Kumar C Rohit; V V Mithun; Chaitra K N Gowda; A B Deepa
Journal:  Breast Dis       Date:  2015

4.  Can Steroids plus Surgery Become a First-Line Treatment of Idiopathic Granulomatous Mastitis?

Authors:  Hasan Karanlik; Ilker Ozgur; Serife Simsek; Alisan Fathalizadeh; Mustafa Tukenmez; Dilek Sahin; Memduh Dursun; Sidika Kurul
Journal:  Breast Care (Basel)       Date:  2014-10       Impact factor: 2.860

5.  A Comparative Study of Conservative versus Surgical Treatment Protocols for 77 Patients with Idiopathic Granulomatous Mastitis.

Authors:  Hakan Yabanoğlu; Tamer Çolakoğlu; Sedat Belli; Huseyin Ozgur Aytac; Filiz Aka Bolat; Ayşin Pourbagher; Tugan Tezcaner; Sedat Yildirim; Mehmet Haberal
Journal:  Breast J       Date:  2015-04-10       Impact factor: 2.431

6.  Evaluation of follow-up strategies for corticosteroid therapy of idiopathic granulomatous mastitis.

Authors:  Kenichi Sakurai; Shigeru Fujisaki; Katsuhisa Enomoto; Sadao Amano; Masahiko Sugitani
Journal:  Surg Today       Date:  2011-03-02       Impact factor: 2.549

7.  Idiopathic granulomatous lobular mastitis - report of 43 cases from iran; introducing a preliminary clinical practice guideline.

Authors:  Ramesh Omranipour; S-Farzad Mohammadi; Parisa Samimi
Journal:  Breast Care (Basel)       Date:  2013-12       Impact factor: 2.860

8.  Etiologic revelation and outcome of the surgical management of idiopathic granulomatous mastitis; An Egyptian centre experience.

Authors:  Islam A Elzahaby; Ashraf Khater; Adel Fathi; Islam Hany; Mohamed Abdelkhalek; Khaled Gaballah; Amr Elalfy; Omar Hamdy
Journal:  Breast Dis       Date:  2016

9.  Temporal resolution of idiopathic granulomatous mastitis with resumption of bromocriptine therapy for prolactinoma.

Authors:  Marcia E Bouton; Lisa M Winton; Sonal G Gandhi; Lakshmi Jayaram; Prahladbhai N Patel; Patrick J O' Neill; Ian K Komenaka
Journal:  Int J Surg Case Rep       Date:  2015-03-04

10.  Granulomatous Mastitis: A Rare Cause of Male Breast Lump.

Authors:  Abdel Rahman A Al Manasra; Mohammad F Al-Hurani
Journal:  Case Rep Oncol       Date:  2016-08-31
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  1 in total

1.  Postoperative Yanghe decoction regimen improves outcomes for idiopathic granulomatous mastitis: A retrospective cohort study.

Authors:  Xing Zhang; Jing Li; Xian-Jie Hu
Journal:  Medicine (Baltimore)       Date:  2020-11-06       Impact factor: 1.817

  1 in total

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