Literature DB >> 27612044

Etiologic revelation and outcome of the surgical management of idiopathic granulomatous mastitis; An Egyptian centre experience.

Islam A Elzahaby, Ashraf Khater, Adel Fathi, Islam Hany, Mohamed Abdelkhalek, Khaled Gaballah, Amr Elalfy, Omar Hamdy.   

Abstract

INTRODUCTION: Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory condition that is confused with cancer. It usually affects women in child bearing age. The exact aetiology and pathogenesis are still unknown, and the optimal therapeutic modality has not yet been established. Treatment most frequently includes Antibiotics, corticosteroids and immunosuppressant, surgical excision, and even mastectomy.
MATERIAL AND METHODS: We studied a thirty cases diagnosed with IGM in our locality to find out the leading risk factors and the outcome of our surgical approach which involves excision of the lesion in continuity with duct system. Patients demographic data, history related to lactation and outcome were recorded.
RESULTS: All patients were parous women with history of previous breast feeding for all kids. Twenty-six patients (86.66%) had a history of early incomplete nursing care to the affected breast. After our surgical approach, Twenty eight (93.3%) patients showed fast recovery with no detectable recurrences in the median follow up period (18 months) with acceptable cosmoses.
CONCLUSION: History of breast feeding together with early failure of complete nursing from a single breast is the most important risk factors for development of IGM in young aged women. Surgery plays an important role in treating IGM, however, it should be directed towards excision of the present mass (s) together with the pathological and colonized duct system.

Entities:  

Keywords:  Granulomatous; mastitis; surgery; treatment

Mesh:

Year:  2016        PMID: 27612044     DOI: 10.3233/BD-160238

Source DB:  PubMed          Journal:  Breast Dis        ISSN: 0888-6008


  5 in total

1.  A clinical observation of stage I implant breast reconstruction for mass-like granulomatous lobular mastitis.

Authors:  Chaojie Zhang; Yaqin Wu; Huiling Wang; Jie Zeng; Shanshan Lei; Jie He; Zheng Zeng; Runzhang Wu; Qian Li; Peizhi Fan
Journal:  Gland Surg       Date:  2021-09

2.  Is idiopathic granulomatous mastitis a surgical disease? The jury is still out.

Authors:  Demetrios Moris; Christos Damaskos; Spyridon Davakis; Michail Vailas; Nikolaos Garmpis; Eleftherios Spartalis; Michael Kontos; Konstantinos Kontzoglou
Journal:  Ann Transl Med       Date:  2017-08

3.  Red flags for the differential diagnosis of granulomatous mastitis: a case report.

Authors:  Richard Chalmers; Patrick McClellan; Vixey Silva; Natalie Shutt; Carolina Restini
Journal:  J Med Case Rep       Date:  2020-11-10

Review 4.  Mastitis in Autoimmune Diseases: Review of the Literature, Diagnostic Pathway, and Pathophysiological Key Players.

Authors:  Radjiv Goulabchand; Assia Hafidi; Philippe Van de Perre; Ingrid Millet; Alexandre Thibault Jacques Maria; Jacques Morel; Alain Le Quellec; Hélène Perrochia; Philippe Guilpain
Journal:  J Clin Med       Date:  2020-03-30       Impact factor: 4.964

5.  Postoperative Yanghe decoction regimen improves outcomes for idiopathic granulomatous mastitis: A retrospective cohort study.

Authors:  Xing Zhang; Jing Li; Xian-Jie Hu
Journal:  Medicine (Baltimore)       Date:  2020-11-06       Impact factor: 1.817

  5 in total

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