Literature DB >> 28856051

Line scanning, stage scanning confocal microscope (LSSSCM).

Daniel S Gareau1, James G Krueger1, Jason E Hawkes1, Samantha R Lish1, Michael P Dietz1, Alba Guembe Mülberger1, Euphemia W Mu2, Mary L Stevenson2, Jesse M Lewin3, Shane A Meehan2, John A Carucci2.   

Abstract

For rapid pathological assessment of large surgical tissue excisions with cellular resolution, we present a line scanning, stage scanning confocal microscope (LSSSCM). LSSSCM uses no scanning mirrors. Laser light is focused with a single cylindrical lens to a line of diffraction-limited width directly into the (Z) sample focal plane, which is parallel to and near the flattened specimen surface. Semi-confocal optical sections are derived from the linear array distribution (Y) and a single mechanical drive that moves the sample parallel to the focal plane and perpendicular to the focused line (X). LSSSCM demonstrates cellular resolution in the conditions of high nuclear density within micronodular basal cell carcinoma.

Entities:  

Keywords:  (110.0180) Microscopy; (170.1790) Confocal microscopy; (170.1870) Dermatology; (170.5810) Scanning microscopy; (170.7050) Turbid media

Year:  2017        PMID： 28856051      PMCID： PMC5560842          DOI： 10.1364/BOE.8.003807

Source DB:  PubMed          Journal:  Biomed Opt Express        ISSN： 2156-7085            Impact factor:   3.732


  24 in total

1.  Parallel line scanning ophthalmoscope for retinal imaging.

Authors:  Kari V Vienola; Mathi Damodaran; Boy Braaf; Koenraad A Vermeer; Johannes F de Boer
Journal:  Opt Lett       Date:  2015-11-15       Impact factor: 3.776

2.  High-speed confocal fluorescence imaging with a novel line scanning microscope.

Authors:  Ralf Wolleschensky; Bernhard Zimmermann; Michael Kempe
Journal:  J Biomed Opt       Date:  2006 Nov-Dec       Impact factor: 3.170

3.  Confocal mosaicing microscopy in Mohs skin excisions: feasibility of rapid surgical pathology.

Authors:  Daniel S Gareau; Yongbiao Li; Billy Huang; Zach Eastman; Kishwer S Nehal; Milind Rajadhyaksha
Journal:  J Biomed Opt       Date:  2008 Sep-Oct       Impact factor: 3.170

4.  Ex vivo fluorescence confocal microscopy for fast evaluation of tumour margins during Mohs surgery.

Authors:  A Bennàssar; A Vilata; S Puig; J Malvehy
Journal:  Br J Dermatol       Date:  2014-02       Impact factor: 9.302

5.  Feasibility of digitally stained multimodal confocal mosaics to simulate histopathology.

Authors:  Daniel S Gareau
Journal:  J Biomed Opt       Date:  2009 May-Jun       Impact factor: 3.170

6.  AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: a report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery.

Authors:  Suzanne M Connolly; Diane R Baker; Brett M Coldiron; Michael J Fazio; Paul A Storrs; Allison T Vidimos; Mark J Zalla; Jerry D Brewer; Wendy Smith Begolka; Timothy G Berger; Michael Bigby; Jean L Bolognia; David G Brodland; Scott Collins; Terrence A Cronin; Mark V Dahl; Jane M Grant-Kels; C William Hanke; George J Hruza; William D James; Clifford Warren Lober; Elizabeth I McBurney; Scott A Norton; Randall K Roenigk; Ronald G Wheeland; Oliver J Wisco
Journal:  J Am Acad Dermatol       Date:  2012-09-05       Impact factor: 11.527

7.  Cost effectiveness of Mohs micrographic surgery.

Authors:  Robert S Stern
Journal:  J Invest Dermatol       Date:  2013-05       Impact factor: 8.551

8.  Use of Digitally Stained Multimodal Confocal Mosaic Images to Screen for Nonmelanoma Skin Cancer.

Authors:  Euphemia W Mu; Jesse M Lewin; Mary L Stevenson; Shane A Meehan; John A Carucci; Daniel S Gareau
Journal:  JAMA Dermatol       Date:  2016-12-01       Impact factor: 10.282

9.  Incidence Estimate of Nonmelanoma Skin Cancer (Keratinocyte Carcinomas) in the U.S. Population, 2012.

Authors:  Howard W Rogers; Martin A Weinstock; Steven R Feldman; Brett M Coldiron
Journal:  JAMA Dermatol       Date:  2015-10       Impact factor: 10.282

10.  In vivo confocal scanning laser microscopy of human skin: melanin provides strong contrast.

Authors:  M Rajadhyaksha; M Grossman; D Esterowitz; R H Webb; R R Anderson
Journal:  J Invest Dermatol       Date:  1995-06       Impact factor: 8.551
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  2 in total

1.  Investigation of confocal microscopy for differentiation of renal cell carcinoma versus benign tissue. Can an optical biopsy be performed?

Authors:  Michael C Phung; Andrew R Rouse; Jayce Pangilinan; Robert C Bell; Erika R Bracamonte; Sharfuddeen Mashi; Arthur F Gmitro; Benjamin R Lee
Journal:  Asian J Urol       Date:  2019-12-24

2.  Deep learning automated pathology in ex vivo microscopy.

Authors:  Marc Combalia; Sergio Garcia; Josep Malvehy; Susana Puig; Alba Guembe Mülberger; James Browning; Sandra Garcet; James G Krueger; Samantha R Lish; Rivka Lax; Jeannie Ren; Mary Stevenson; Nicole Doudican; John A Carucci; Manu Jain; Kevin White; Jaroslav Rakos; Daniel S Gareau
Journal:  Biomed Opt Express       Date:  2021-05-05       Impact factor: 3.562
  2 in total

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