Literature DB >> 2885257

Rapid RFLP screening procedure identifies new polymorphisms at albumin and alcohol dehydrogenase loci.

J C Murray, R Shiang, L R Carlock, M Smith, K H Buetow.   

Abstract

A rapid screening procedure for restriction fragment length polymorphisms (RFLPs) is reported. DNA from ten individuals is pooled and compared to DNA isolated from a cell line containing a single chromosome 4. This single chromosome-containing line is an obligate hemizygote for chromosome 4 RFLPs so that only one band corresponding to a single allele will appear on a Southern blot. In the pooled DNA sample lane bands corresponding to both alleles will be seen. The technique allows for efficient detection of RFLPs with easier use of large numbers of enzymes. It provides estimates of allele frequencies and disequilibrium. New RFLPs for albumin and alcohol dehydrogenase detected with this technique are described.

Mesh：

Substances：

Year:  1987        PMID： 2885257     DOI： 10.1007/bf00283622

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  18 in total

1.  Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11-22 of human chromosome 4.

Authors:  M E Harper; A Dugaiczyk
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

2.  Strategies for detecting and characterizing restriction fragment length polymorphisms (RFLP's).

Authors:  M H Skolnick; R White
Journal:  Cytogenet Cell Genet       Date:  1982

3.  "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1984-02       Impact factor: 3.365

4.  A strategy to reveal high-frequency RFLPs along the human X chromosome.

Authors:  J Aldridge; L Kunkel; G Bruns; U Tantravahi; M Lalande; T Brewster; E Moreau; M Wilson; W Bromley; T Roderick
Journal:  Am J Hum Genet       Date:  1984-05       Impact factor: 11.025

5.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

6.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

7.  Molecular genetics of human serum albumin: restriction enzyme fragment length polymorphisms and analbuminemia.

Authors:  J C Murray; C M Demopulos; R M Lawn; A G Motulsky
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

8.  Mechanism of origin of complete hydatidiform moles.

Authors:  P A Jacobs; C M Wilson; J A Sprenkle; N B Rosenshein; B R Migeon
Journal:  Nature       Date:  1980-08-14       Impact factor: 49.962

9.  RFLPs for epidermal growth factor (EGF), a single copy sequence at 4q25-4q27.

Authors:  J C Murray; C R DeHaven; G I Bell
Journal:  Nucleic Acids Res       Date:  1986-06-25       Impact factor: 16.971

10.  Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker.

Authors:  L C Tsui; M Buchwald; D Barker; J C Braman; R Knowlton; J W Schumm; H Eiberg; J Mohr; D Kennedy; N Plavsic
Journal:  Science       Date:  1985-11-29       Impact factor: 47.728
View more
  10 in total

1.  A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity.

Authors:  Michael V Osier; Andrew J Pakstis; Himla Soodyall; David Comas; David Goldman; Adekunle Odunsi; Friday Okonofua; Josef Parnas; Leslie O Schulz; Jaume Bertranpetit; Batsheva Bonne-Tamir; Ru-Band Lu; Judith R Kidd; Kenneth K Kidd
Journal:  Am J Hum Genet       Date:  2002-06-05       Impact factor: 11.025

2.  Localisation of RFLPs of the medium chain acyl-CoA dehydrogenase gene.

Authors:  A I Blakemore; S Kolvraa; N Gregersen; P C Engel; D Curtis
Journal:  Hum Genet       Date:  1991-03       Impact factor: 4.132

3.  Albumin--vitamin D-binding protein haplotypes in Asian-Pacific populations.

Authors:  L Z Chen; S Easteal; P G Board; K M Summers; K K Bhatia; R L Kirk
Journal:  Hum Genet       Date:  1990-06       Impact factor: 4.132

4.  New informative polymorphism at the DXS304 locus, a close distal marker for the fragile X locus.

Authors:  F Rousseau; A Vincent; I Oberlé; J L Mandel
Journal:  Hum Genet       Date:  1990-02       Impact factor: 4.132

5.  A Pvu II RFLP in the human ADH3 gene.

Authors:  M Pandolfo; M Smith
Journal:  Nucleic Acids Res       Date:  1988-12-23       Impact factor: 16.971

6.  Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.

Authors:  B Peral; C J Ward; J L San Millán; S Thomas; R L Stallings; F Moreno; P C Harris
Journal:  Am J Hum Genet       Date:  1994-05       Impact factor: 11.025

7.  A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates.

Authors:  K H Buetow; R Shiang; P Yang; Y Nakamura; G M Lathrop; R White; J J Wasmuth; S Wood; L D Berdahl; N J Leysens
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025

8.  Genetic mapping near the myd locus on mouse chromosome 8.

Authors:  K A Mills; K D Mathews; T Scherpbier-Heddema; R L Schelper; R Schmalzel; H L Bailey; J H Nadeau; K H Buetow; J C Murray
Journal:  Mamm Genome       Date:  1995-04       Impact factor: 2.957

9.  Alcohol dehydrogenase genes: restriction fragment length polymorphisms for ADH4 (pi-ADH) and ADH5 (chi-ADH) and construction of haplotypes among different ADH classes.

Authors:  K Edman; W Maret
Journal:  Hum Genet       Date:  1992-12       Impact factor: 4.132

10.  Additional polymorphisms at marker loci D9S5 and D9S15 generate extended haplotypes in linkage disequilibrium with Friedreich ataxia.

Authors:  R Fujita; A Hanauer; G Sirugo; R Heilig; J L Mandel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.