Literature DB >> 2885163

DNA sequence and regional assignment of the human follicle-stimulating hormone beta-subunit gene to the short arm of human chromosome 11.

P C Watkins, R Eddy, A K Beck, V Vellucci, B Leverone, R E Tanzi, J F Gusella, T B Shows.   

Abstract

A human genomic DNA fragment in phage lambda containing FSHB, the gene for the beta-subunit of human follicle-stimulating hormone (FSH-beta), was analyzed and the nucleotide sequence of the region of the clone encoding FSH-beta was determined. A subclone of the lambda phage containing 67% of FSH-beta coding sequence was used as hybridization probe to determine the human chromosomal location of FSHB. A panel of mouse-human somatic cell hybrids containing reduced numbers of human chromosomes was screened with the FSHB probe; complete cosegregation of FSHB with human chromosome 11 was observed in all 26 cell hybrids tested. Analysis of a set of cell hybrids containing translocated derivatives of chromosome 11 further localized FSHB to the human chromosome region 11p11.2----11pter. A Hind III restriction fragment length polymorphism (RFLP) detected by another subclone of the lambda phage containing FSHB now provides a genetic marker for this region of the human genome.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 2885163     DOI： 10.1089/dna.1987.6.205

Source DB:  PubMed          Journal:  DNA        ISSN： 0198-0238


  25 in total

Review 1.  Molecular structures of glycoprotein hormones and functions of their carbohydrate components.

Authors:  A Stockell Hartree; A G Renwick
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

2.  The potassium channel gene HK1 maps to human chromosome 11p14.1, close to the FSHB gene.

Authors:  M Gessler; A Grupe; K H Grzeschik; O Pongs
Journal:  Hum Genet       Date:  1992-11       Impact factor: 4.132

3.  MspI RFLP of FSHB on chromosome 11p.

Authors:  S C Healey; M Southall; N G Martin; G Chenevix-Trench
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

Review 4.  Mouse chromosome 2.

Authors:  L D Siracusa; C M Abbott
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

5.  Somatic cell hybrid and long-range physical mapping of 11p13 microdissected genomic clones.

Authors:  L M Davis; G Senger; H J Lüdecke; U Claussen; B Horsthemke; S S Zhang; B Metzroth; K Hohenfellner; B Zabel; T B Shows
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

6.  A deletion map of the WAGR region on chromosome 11.

Authors:  M Gessler; G H Thomas; P Couillin; C Junien; B C McGillivray; M Hayden; G Jaschek; G A Bruns
Journal:  Am J Hum Genet       Date:  1989-04       Impact factor: 11.025

7.  Rapid isolation of moderate and highly polymorphic DNA fragments mapping close to WT (Wilms' tumour) and AN2 (aniridia) on chromosome 11.

Authors:  P A Boyd; S Christie; N D Hastie; D J Porteous
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132

8.  Isolation and regional localisation of DNA sequences from a human chromosome 11-specific cosmid library.

Authors:  R B Wadey; P F Little; J Pritchard; J K Cowell
Journal:  Hum Genet       Date:  1990-04       Impact factor: 4.132

9.  Loss of heterozygosity on chromosome 11p13 in primary bladder carcinoma.

Authors:  R Shipman; P Schraml; M Colombi; G Raefle; C U Ludwig
Journal:  Hum Genet       Date:  1993-06       Impact factor: 4.132

10.  Characterization of a panel of somatic cell hybrids for subregional mapping along 11p and within band 11p13. Subdivision of the WAGR complex region.

Authors:  P Couillin; M Azoulay; I Henry; N Ravisé; M C Grisard; C Jeanpierre; F Barichard; P Metezeau; J J Candelier; W Lewis
Journal:  Hum Genet       Date:  1989-05       Impact factor: 4.132
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.